It's likely that lupus results from a combination of your genetics and your environment. It appears that people with an inherited predisposition for lupus may develop the disease when they come into contact with something in the environment that can trigger lupus. The cause of lupus in most cases, however, is unknown.
Anyone can get lupus; however, women get the disease about nine times more often than men. Most often it happens in people between ages 15 and 45 years, but lupus can occur in childhood or later in life as well.
Symptoms and diagnosis occur most often between the ages of 15 and 44. Symptoms of lupus will occur before age 18 in only 15 percent of the people who are later diagnosed with the disease.
Sunlight, stress, smoking, certain medicines, and viruses may trigger symptoms in people who are most likely to get lupus due to their genes. Hormones such as estrogen. Lupus is more common in women during their childbearing years when estrogen levels are highest.
Lupus can be diagnosed at any age
Between 10 and 20 percent of people with systemic lupus are diagnosed before age 18, according to a study in Nature Reviews Rheumatology, and adults can also have “late-onset” lupus that is diagnosed after age 50.
No two cases of lupus are exactly alike. Signs and symptoms may come on suddenly or develop slowly, may be mild or severe, and may be temporary or permanent.
Lupus symptoms can also be unclear, can come and go, and can change. On average, it takes nearly six years for people with lupus to be diagnosed, from the time they first notice their lupus symptoms.
Gender: Even though anyone can get lupus, it most often affects women. They're nine to ten times more likely than men to develop it. Age: Lupus can occur at any age, but most are diagnosed in their 20s and 30s. Race: Lupus is two to three times more common in African-American women than in Caucasian women.
With close follow-up and treatment, 80-90% of people with lupus can expect to live a normal life span. It is true that medical science has not yet developed a method for curing lupus, and some people do die from the disease. However, for the majority of people living with the disease today, it will not be fatal.
Systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS) may coexist, and they are chronic complex disorders, with an autoimmune background, multifactorial etiology, multiple circulating autoantibodies, and variable prognosis.
Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus.
The first symptoms of lupus usually occur somewhere between the teen years and the 30s and may be mild, severe, sporadic, or continual. Common general symptoms include fatigue, fever, and hair loss. Lupus can also affect individual organs and body parts, such as the skin, kidneys, and joints.
Although doctors haven't proven that stress is a direct cause of lupus, it's known to trigger flare-ups in people who already have the disease. Stressful events that can make symptoms worse include: A death in the family. Divorce.
Lupus is a chronic inflammatory autoimmune disease with a wide range of clinical presentations resulting from its effect on multiple organ systems. There are four main types of lupus: neonatal, discoid, drug-induced, and systemic lupus erythematosus (SLE), the type that affects the majority of patients.
Lupus can be hard to diagnose because it has many symptoms that are often mistaken for symptoms of other diseases. Many people have lupus for a while before they find out they have it. If you have symptoms of lupus, tell your doctor right away.
Prevention Tips
Exposure to UV rays from sunlight and other light sources can trigger flares in many people with lupus. Staying out of the sun between 10 a.m. and 4 p.m., applying sunscreen every day, and wearing sun-protective clothing can prevent UV rays from triggering a lupus flare.
Lupus is a lifelong disease that can affect many parts of your life. But, many women with lupus live long, healthy lives. You can take steps to control your symptoms, prevent lupus flares, and cope with the challenges of lupus.
For example, untreated lupus can lead to blood disorders such as anemia or thrombosis. Other potential serious complications include: Chronic digestive distress that could include difficulty swallowing, dry mouth, indigestion, intestinal inflammation, liver enlargement, or pain when vomiting or feeling nauseous.
The seriousness of SLE can range from mild to life-threatening. The disease should be treated by a doctor or a team of doctors who specialize in care of SLE patients. People with lupus that get proper medical care, preventive care, and education can significantly improve function and quality of life.
No one test can diagnose lupus. The combination of blood and urine tests, signs and symptoms, and physical examination findings leads to the diagnosis.
For some people, living with and managing lupus can cause weight gain. Weight gain may also lead to worsening lupus symptoms and complications associated with obesity. Some potential causes of weight gain that relate to lupus may include: being a side effect of medications such as corticosteroids.
Systemic Lupus Erythematosus (SLE), also known as lupus, is a disease of the immune system, which is estimated to affect more than 20,000 people in Australia and New Zealand.
With age, symptom activity with lupus often declines, but symptoms you already have may grow more severe. The accumulation of damage over years may result in the need for joint replacements or other treatments.
In some people, lupus will flare, become inactive (quiescent), and go into remission—this course of the disease may or may not occur regularly throughout their life. In other people, lupus will remain in a chronic (long-lasting) state of activity. Some people will have fairly frequent flares of illness.