Sure, Goku has more feats, more forms, and more advantages, but he won't physically be able to hurt Saitama. Plus, I believe that Goku would actually just befriend Saitama instead of killing him. Since they both are lovers for food and are both very strong, they would probably make very good training buddies instead.
Going by the facts offered by the last chapter, it can be argued that Goku has fought against opponents with equal or more strength than Saitama's in Dragon Ball's history. So a single Serious Punch from the bald hero would not be enough to destroy him as of yet.
Goku wins this. Sure, Goku risky fighting style may lead Saitama to outpace him from time to time - but Goku has just that much raw power that Saitama simply lacks. Not to mention, we know he's smart enough to use his highest Kaiohken in a last burst, since it's exactly what he did against Frieza.
Thus, it is safe to say that Limit-breaker Saitama cannot beat Goku in his Ultra Instinct form. It is far too powerful a transformation to contend with. Even if Bald Cape lands his Zero Punch, Goku has been seen multiple times being more than capable of taking a hit.
As of now, nothing in his universe is able to physically hurt Saitama.
The mere comparison of strength between the two characters is crazy. Goku is an extraterrestrial being who has to lose a fight in order to get stronger. Saitama is a man that can defeat any foe with a single punch. If the two of them were to face off in a one-on-one battle, Saitama would easily win.
At one point, the protagonist of One Punch Man even slapped himself. While he gave himself a huge red mark, he seemed mostly unaffected by it, which suggests that he could likely withstand his own punch as well.
With each hit Vegeta takes, his power increases by unleashing his emotional controls and letting him lean into the fight. The advantage of Ultra Ego against Saitama is that not only would it allow Vegeta to take Saitama's signature punch, but will make him stronger as a result.
Zeno from Dragon Ball Super couldn't just defeat Saitama but could put an end to everyone in the One Punch Man universe. He is the god of the multiverse and is so strong that he can wipe out the entire universe with a single thought. If Saitama infuriates Zeno, he can kill him without even raising his hand.
One-Punch Man Is Officially Faster Than Goku (& It's Not Even Close) Thanks to learning the Zero Causality Fist, the pinnacle of Garou's martial arts, Saitama is now theoretically MUCH faster than Dragon Ball's Goku.
Immeasurable Strength: Saitama possesses an immeasurable amount strength and as a result is capable of destroying powerful monsters and villains with a single one punch (though this strength is not limited to punches).
This matchup is too close to decide with absolute certainty, but, in all likelihood, Saitama would claim victory. The fight would ultimately come down to who can last the longest, and Saitama is physically unmatched in every regard. A single punch would floor Goku, but the Zenkai Boost may not be enough to help.
Super Saiyan 3 Goku at full power has a battle power of 24,000,000,000, 2 billion above Kid Buu's level.
It would be tough for Saitama to punch Beerus, seeing how this God was able to easily evade all of Goku's attacks even in his Super Saiyan form. Even when Goku becomes a Super Saiyan God, Beerus is able to defeat him after a mighty battle.
Boros. Boros was the first on-screen opponent of Saitama that survived after getting punched, much to his surprise. In his fight with Saitama, Boros was hit with 3 normal punches, a Consecutive Normal Punches attack, as well as the shockwave from the hero's Serious Punch.
He exhibits the same strength effortlessly and yet still has more room for growth. At this point, he hasn't ever needed to use his full power, whereas Goku frequently needs to reach his limits. All in all, Saitama wins this competition.
Saitama might be powerful, but even his physical strength cannot match Goku's strength. It should also be noted how Goku's Ultra instinct essentially scared the gods of destruction. Whether they're in the One Punch Man or Dragon Ball universe, Goku would easily be able to kill Saitama without much effort.
Unfortunately, since Saitama cannot also elevate his strength into another form, it would be unfair to compare Super Saiyan Goku to base Saitama. In terms of base form strength, Saitama from One Punch man takes home the win against Goku.
With that settled, the incredible energy on display here confirms that Saitama outmuscles even Kid Buu, making him a one-punch powerhouse even by the cosmic standards of Dragon Ball.
It is for this very reason that one can confidently suggest that Broly doesn't stand a chance against Saitama, especially if the One Punch Man protagonist decides to get serious and use the Zero Causality Fist.
Now, readers learned that not only Saitama is capable of suffering, but he is also afraid of completely losing his humanity, and this is why he kept close to friends like Genos, King, and even Bang, despite his apparent annoyance towards them.
The main character, Saitama, displays signs of severe depression. This is demonstrated through his transformation from an average person to the most powerful superhero in the world of One-Punch Man.