Vitiligo is an idiopathic disorder of skin and hair characterized by melanin loss. Nonetheless thyroid disorder is a major cause of this pathology, other factors participate in its expression. Hormones such as, testosterone and estrogen have been suspected as drivers of this disorder.
Known vitiligo triggers include: A severe sunburn. Injured skin (cut, scrape, burn) Getting a strong chemical like phenol on your skin.
Results from a review in Frontiers in Endocrinology found that, among people with vitiligo, the most common thyroid diseases were: hypothyroidism. subclinical hypothyroidism, which is a milder form of the condition. Hashimoto's thyroiditis, which is a specific type of AITD.
Endocrine disorders associated with vitiligo include Addison's disease and diabetes. Vitiligo-associated dermatologic disorders include alopecia areata, atopic dermatitis, and psoriasis [15,16].
Several studies have suggested vitiligo is associated with a variety of other autoimmune diseases, including thyroid conditions, alopecia areata, type 1 diabetes mellitus, pernicious anemia, and rheumatoid arthritis.
Vitiligo is an idiopathic disorder of skin and hair characterized by melanin loss. Nonetheless thyroid disorder is a major cause of this pathology, other factors participate in its expression. Hormones such as, testosterone and estrogen have been suspected as drivers of this disorder.
About 15 to 25 percent of people with vitiligo are also affected by at least one other autoimmune disorder, particularly autoimmune thyroid disease, rheumatoid arthritis, type 1 diabetes, psoriasis , pernicious anemia, Addison disease, systemic lupus erythematosus, celiac disease, Crohn's disease, or ulcerative colitis ...
Based on our findings, patients with vitiligo have a high incidence of vitamin D deficiency, and this deficiency is more common among females than males.
Pityriasis versicolor can sometimes be confused with vitiligo, as they both cause the skin to become discoloured in patches. But there are ways to tell the difference: vitiligo often develops symmetrically (on both sides of your body at the same time), while pityriasis versicolor may not.
Stress increases the levels of catecholamines, neuropeptides, and cortisol that are higher in vitiligo patients [37–39] suggesting their role in the pathogenesis of vitiligo.
Vitiligo is an under-recognized organ-specific autoimmune disease of the skin that results from cytotoxic T cell-mediated attack on melanocytes, the pigment-producing cells in the epidermis (18). The result is the loss of pigment in the skin, visible as white spots (Fig. 1) (19).
Vitiligo is an autoimmune disease of the skin, which means that someone with vitiligo has an immune system that is malfunctioning in a small way.
While researchers are looking for a cure, treatment cannot currently cure this disease. Treatment can help restore lost skin color, but the color (repigmentation) may fade over time. To keep their results, many patients have maintenance treatments.
-B12 deficiency can cause white spots on the skin, called vitiligo. The deficiency can affect the melanin production and lead to loss of pigmentation in certain areas of the skin.
Vitiligo often starts as a pale patch of skin that gradually turns completely white. The centre of a patch may be white, with paler skin around it. If there are blood vessels under the skin, the patch may be slightly pink, rather than white. The edges of the patch may be smooth or irregular.
Signs and symptoms of vitiligo include: Patches of skin or mucous membranes that lose color. These can appear white or lighter than your natural skin tone. Patches of hair on your body turn silver, gray or white.
Vitamin B12 and Folic Acid
This is why it is always recommended to take these two vitamins together in order to treat vitiligo. According to some scientific studies, a combination of vitamin B12 and folic acid supplementation and sun exposure is a good strategy to regain natural skin color.
It is also advised to avoid milk and milk products to some extent as milk protein may reduce the re-pigmentation cycle. Black/Red gram or Desi-chana (Chickpeas), Black dates, Red Radish, Beetroot and Carrot are helpful in Vitiligo and considered as Vitiligo diet.
Vitiligo seems to be more common in people who have a family history of the disorder or who have certain autoimmune diseases, including: Addison's disease. Pernicious anemia. Psoriasis.
Vitiligo patients with the NSV form of the disease are more likely to have another autoimmune disorder, with Hashimoto's being the most common. And Hashimoto's is the number one cause of hypothyroidism (low thyroid hormone levels).
As non-segmental vitiligo is closely associated with other autoimmune conditions, you may be assessed to see whether you have any symptoms that could suggest an autoimmune condition, such as: being tired and lacking energy (signs of Addison's disease) being thirsty and needing to urinate often (signs of diabetes)