So although it isn't guaranteed to work every time, with a little practice, preparation and effort, Vibranium is strong enough to cause serious damage to the Hulk, strongly hinting that the powerful metal is strong enough to effectively restrain him as well.
In Ultimate Avengers II Vibranium was shown to be largely useless against the Hulk because it becomes brittle when exposed to the Gamma radiation emitted by him when he becomes especially angry.
Even the most powerful substances have their weaknesses, and Vibranium is no exception. The Wakandan metal, although near indestructible, is shown to be able to melt under the heat produced by the Mind Stone, when coupled with a single lightning bolt, courtesy of Thor's (Chris Hemsworth) Mjølnir.
Anything could cut the hulk really (at least in the films). It's just that his super powerful healing factor would heal it in seconds.
Could Hulk break Captain America's shield? Nope. Raw strength cannot destroy Captain America's shield.
Still, while the Hulk has the brawn, his brain is lacking. There have been other heroes who have gotten ahead of him just with their smarts and careful planning. Obviously, big hitters like Sentry, Galactus, and even Superman have been able to withstand the emerald giant's assault.
So although it isn't guaranteed to work every time, with a little practice, preparation and effort, Vibranium is strong enough to cause serious damage to the Hulk, strongly hinting that the powerful metal is strong enough to effectively restrain him as well.
Because of the thickness and strength of the Hulk's skin, it's nearly impossible for any form of artillery to hurt him. Sure, everyone's seen bullets bounce off of the Hulk, but when we say he's bulletproof what we really mean is he's BULLETPROOF.
Due to the gamma radiation that birthed him, his skin is nearly indestructible and takes massive force to break. Throughout Hulk's many on-screen fights, he has only bled twice, and both circumstances prove it takes a unique set of variables to accomplish that.
The Hulk's strength remains at the top level of all super human beings on Earth and increases exponentially as his anger grows. This strength grants him not only upper body prowess, but also the ability to leap great distances and land without harm to himself.
The Strength and Weakness of Vibranium
The shield itself was able to withstand a hit from Thor's hammer, Mjolnir, though Thanos managed to break the shield with his sword (which is never explained, though may be made out of Vibranium itself).
Unlike adamantum, Magneto cannot manipulate vibranium – not if it's pure. Vibranium is a rare, extraterrestrial metallic ore. It has near-mystical properties that allow for energy manipulation and more. There is a Wakandan isotope and an Antarctic isotope, and both of them are completely unaffected by Magneto's powers.
Only an Uru blade would be capable of out powering Cap's shield in the Marvel Comic Universe. Vibranium is the strongest metle on earth. Adamantium is strong but not as vibranium so caps shield cannot be tear apart by logans claws. Only even few has broken the caps shield such as meastro etc.
Even if Hulk does manage to land a punch to Thor, being a god he can take it and keep on going. All in all said, Thor was a whole can defeat Hulk. A large part of that is being able to wield Mjolnir. Hulk cannot keep up with or match Thor when fighting with this might weapon.
Weakness: ADAMANTIUM AND VIBRANIUM
Swords, knives, and more have been used against Hulk and almost none of them even leave a scratch or mark on him. However, with that said, there are two bladed weapons that can cut into Hulk's skin. Adamantium is something that can cause damage to Hulk.
Bruce explains that Hulks metabolize alcohol at an incredible rate and thus cannot get drunk, thus their drinking sessions are, "All buzz, no barf." The "buzz" experienced while consuming alcohol is a stage of drunkenness. If they cannot get drunk, they cannot get a buzz.
History. During the time Bruce Banner lived in Rio de Janeiro, he worked in the Pingo Doce Bottling Plant. After Banner was cut, his gamma-irradiated blood dripped into one of the bottles where it was eventually drunk by the Watcher Informant in Milwaukee.
However, as far as Earth-based weapons, there are two things that have pierced Hulk's skin in Marvel Comics -- Adamantium and Vibranium.
But Hulk's is so fast, Wolverine didn't even know Hulk had one until he faced off against the Grey Hulk, whose healing factor was a bit slower. As he healed around 90% of his body mass within seconds, including his eyes.
Yes, The Hulk can survive a nuclear blast at ground zero. In fact, nuke & gamma bombs and the like are used against him quite often. Here are few times the hulk has had massive explosions used against him. From his early days of comics to his more recent events.
Warning: contains spoilers for Devil's Reign: Spider-Man #1! Marvel fans know that Spider-Man is a strong superhero, but the company has just confirmed that Peter Parker is strong enough to defeat the Incredible Hulk in a one-on-one brawl.
Fans know Spider-Man is strong, but Marvel confirms Peter Parker has the strength to not only survive a Hulk attack, but take him down too.
With the Iron Fist, his physicality is boosted immensely as he has been able to physically harm the likes of Hulk and Nul the World Breaker as well as sent beings like Colossus and Skaar (Hulk's son) with a single punch.
Few characters can stand against him, with only a few being so brave and some being very foolish. While the MCU Hulk was not able to defeat Thanos, his comic book counterparts pose a better chance to make an even fight particularly if Thanos does not wield the Infinity Gauntlet.