A: Yes. There have been several clinical studies — many of them done here at Cleveland Clinic — that show statins can reverse plaque buildup. Two statins in particular, atorvastatin, which is sold under the brand name Lipitor, and
Blocked arteries caused by plaque buildup and blood clots are the leading cause of death in the U.S. Reducing cholesterol and other risk factors can help prevent cholesterol plaques from forming. Occasionally, it can even reverse some plaque buildup.
Statins and Higher Calcium Scores
Evidence supports the idea that statin therapy not only reduces cholesterol levels but also changes existing plaques to make them less dangerous. As part of this process, the plaques may become more calcified—and thus, the calcium score goes up.
If you have the gumption to make major changes to your lifestyle, you can, indeed, reverse coronary artery disease. This disease is the accumulation of cholesterol-laden plaque inside the arteries nourishing your heart, a process known as atherosclerosis.
Yes, lifestyle changes, including diet, smoking cessation, stress management and exercise, can decrease the size of atherosclerotic plaques. They can also help to stabilize them so that they are less likely to break off and block blood flow, decreasing your risk of a heart attack.
and initial plaque reversal is demonstrable within 1 or 2 years thereafter.
Statins help lower low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol, in the blood. They draw cholesterol out of plaque and stabilize plaque, Blaha says.
The American College of Cardiology and American Heart Association developed some prescription guidelines. Typically, if a person's LDL cholesterol (bad cholesterol) is 190 or higher, they're often advised to start a statin.
If you've made lifestyle changes through diet and exercise that have lowered your cholesterol levels, you may not need to continue taking a statin. These changes can help reduce your risk of heart attack, stroke, or blocked arteries while allowing you to take one less medication.
Eat a balanced diet that's high in heart-healthy fruits, vegetables, and fish. Exercise for at least 30 to 60 minutes a day. Stop smoking, cause that's really bad news for your arteries. If your cholesterol is high, ask your doctor whether you should take cholesterol-lowering medication.
Initial magnetic resonance imaging (MRI) studies of the aorta suggested that statin use might result in atherosclerotic plaque regression as early as 6 months after initiation of therapy [2].
Magnesium supplementation can inhibit atherosclerotic plaque formation in animals on high-fat diets. More recent human studies have revealed strong associations between low magnesium levels and higher heart disease risks. This demonstrates that magnesium can be a powerful protective measure to maintain heart health.
While statins are highly effective and safe for most people, they have been linked to muscle pain, digestive problems and mental fuzziness in some people. Rarely, they may cause liver damage. If you think you're experiencing side effects from taking statins, don't just stop taking the pills.
A Statin Alternative Lowers Heart Attack Risk by 23 Percent, Drug Trial Shows. People who can't or won't take statin medications to reduce LDL cholesterol may want to talk to their doctor about bempedoic acid (Nexletol).
Statins reduce your cholesterol levels and lower your risk of heart attack and stroke.
Joseph A. Hill, M.D., Ph. D. The controversy in the United Kingdom started in 2013 when the British Medical Journal (BMJ) claimed statins were being overprescribed to people with low risk of heart disease, and that the drugs' side effects were worse than previously thought.
If your risk is very low, you probably won't need a statin, unless your LDL is above 190 mg/dL (4.92 mmol/L). If your risk is very high — for example, you've had a heart attack in the past — a statin may be helpful even if you don't have high cholesterol.
A person's arteries can become clogged when plaques build up inside them, reducing blood flow. Eating specific foods cannot cleanse plaques out of the arteries, but a healthful diet can help manage and prevent heart disease. Over time, plaque buildup can lead to thickened or hardened arteries.
Living healthy with atherosclerosis is possible with proper management, so take steps toward better heart health now. Atherosclerosis doesn't have to be a losing battle. In fact, the disease can be reversed through lifestyle changes, according to the American College of Cardiology.
Atherosclerosis, which causes diseases of the arteries, is a very common process. One of the biggest risk factors for atherosclerosis is age, so it is more common among people in their 60s and 70s, although there are many elderly people who don't have significant atherosclerosis.
In summary, fish oil may reduce atherosclerosis by activating numerous nuclear receptors including PPAR-alpha and PPAR-gamma, by inhibiting the infiltration of macrophages and as the release of MMPs, and by preventing the weakening and rupturing of atherosclerotic plaque.