But beyond blood levels of 21 nanograms per milliliter of 25-Hydroxyvitamin D — considered the low end of the normal range for vitamin D — any additional increase in vitamin D was associated with an increase in CRP, a factor linked to stiffening of the blood vessels and an increased risk of cardiovascular problems.
Very high levels of vitamin D in your blood (greater than 375 nmol/L or 150 ng/mL) can cause nausea, vomiting, muscle weakness, confusion, pain, loss of appetite, dehydration, excessive urination and thirst, and kidney stones.
The main consequence of vitamin D toxicity is a buildup of calcium in your blood (hypercalcemia), which can cause nausea and vomiting, weakness, and frequent urination. Vitamin D toxicity might progress to bone pain and kidney problems, such as the formation of calcium stones.
Because vitamin D toxicity can cause side effects like rapid heartbeat, confusion, restlessness and chest pains, it can potentially cause feelings associated with anxiety.
Vitamin D 1000 mcg (40,000 units)/day causes toxicity within 1 to 4 months in infants. In adults, taking 1250 mcg (50,000 units)/day for several months can cause toxicity. Vitamin D toxicity can occur iatrogenically when hypoparathyroidism.
Some side effects of taking too much vitamin D include weakness, dry mouth, nausea, vomiting, and others. Taking vitamin D for long periods of time in doses higher than 4000 IU (100 mcg) daily is possibly unsafe and may cause very high levels of calcium in the blood.
For less frequent dosage, a higher amount is recommended. Overall, though, studies show that the best results come from taking vitamin D as part of a daily regimen, with dosage at the recommended level.
But how do you flush vitamin D out of your system – and can you even do that? Yes, by ensuring you consume plenty of water. This will encourage urination, allowing your body to shed the excess vitamin D and calcium more quickly. Prescription diuretics like furosemide can also be helpful.
If you are taking a supplement for a true deficiency, such as a low iron, B12, folic acid or vitamin D, then you should consult your doctor before making any changes. But Dr Fenton added: “If however, you have been taking general vitamin supplements, it is absolutely fine to just stop.
Taking too much vitamin D is not good either, as it can lead to hypercalcemia, or high calcium levels, which can also cause irregular heartbeat. Atrial fibrillation (A-fib), one of the most common forms of irregular heartbeat, is a condition in which the heart's upper chambers quiver instead of pump rhythmically.
Excess serum vitamin D levels (>150–250 ng/mL) are also dangerous with possible outcomes such as gastrointestinal disorders (anorexia, nausea, constipation, or diarrhea), hypercalcemia, hypovolemia, cardiac arrhythmias, suppression of parathyroid hormone, and neuropsychiatric disorders [5].
Calcium supplements are usually taken to treat or prevent bone disease, such as osteoporosis. A review of studies found that calcium supplements increased the risk of heart disease, particularly in healthy, postmenopausal women. But other studies have said calcium supplements don't increase the risk.
Confusion, apathy, recurrent vomiting, abdominal pain, polyuria, polydipsia, and dehydration are the most often noted clinical symptoms of vitamin D toxicity (VDT; also called vitamin D intoxication or hypervitaminosis D).
Too much vitamin D can cause harmful high calcium levels. Tell your doctor right away if any of these signs of high vitamin D/calcium levels occur: nausea/vomiting, constipation, loss of appetite, increased thirst, increased urination, mental/mood changes, unusual tiredness.
Vitamin D undergoes two hydroxylations in the body for activation. Calcitriol (1,25-dihydroxyvitamin D3), the active form of vitamin D, has a half-life of about 15 h, while calcidiol (25-hydroxyvitamin D3) has a half-life of about 15 days. [63] Vitamin D binds to receptors located throughout the body.
While vitamin D itself is unlikely to be causing your anxiety, that doesn't mean it can't, and the activities that you do to help increase vitamin D are valuable for your anxiety anyway. Getting outside will help you get what vitamin D you can, although there are also nutritional supplements available.
Extremely high vitamin D levels are harmful and can cause nausea, vomiting, confusion, excessive thirst and kidney stones. Vitamin D supplements can interact with certain medications, so check with your doctor before starting one.
Yes, a vitamin D supplement can help reduce your stress. This is because vitamin D helps to regulate the production of cortisol. If you take a vitamin D supplement, it can help to reduce the amount of cortisol in your body and improve your stress response.
Vitamin D and Anxiety. It seems that more scientists agree about the link between vitamin D deficiency and anxiety than depression. Though, some members of the scientific community are skeptical about how much it helps with anxiety. Regardless, multiple studies find that a vitamin D deficiency may increase anxiety.
In experimental animals, the administration of pharmacological doses of vitamin D sterols can lead to widespread arterial calcification, especially in association with favourable conditions such as atherosclerosis, diabetes and chronic kidney disease (CKD) [ 1–5 ].