Chronic lymphocytic leukemia (CLL). With CLL , the most common chronic adult leukemia, you may feel well for years without needing treatment.
Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test.
CLL doesn't usually cause any symptoms early on and may only be picked up during a blood test carried out for another reason. When symptoms develop, they may include: getting infections often. anaemia – persistent tiredness, shortness of breath and pale skin.
The onset of leukemia can be acute (sudden onset) or chronic (slow onset). In acute leukemia, cancer cells multiply quickly. In chronic leukemia, the disease progresses slowly and early symptoms may be very mild.
Leukemia or myelodysplastic syndromes (MDS) can cause bone or joint pain, usually because your bone marrow has become overcrowded with cancer cells. At times, these cells may form a mass near the spinal cord's nerves or in the joints.
Some symptoms, like night sweats, fever, fatigue and achiness, resemble flu-like symptoms. Unlike symptoms of the flu, which generally subside as you get better, leukemia symptoms generally last longer than two weeks, and may include sudden weight loss, bone and joint pain and easy bleeding or bruising.
By looking at a sample of your blood, your doctor can determine if you have abnormal levels of red or white blood cells or platelets — which may suggest leukemia. A blood test may also show the presence of leukemia cells, though not all types of leukemia cause the leukemia cells to circulate in the blood.
Acute leukemia symptoms can often appear suddenly
With acute leukemia, symptoms tend to develop very quickly. You may suddenly spike a fever that won't go away, develop an infection for no apparent reason, or start bleeding spontaneously from your nose or gums and not be able to stop it.
Acute leukemias — which are incredibly rare — are the most rapidly progressing cancer we know of. The white cells in the blood grow very quickly, over a matter of days to weeks. Sometimes a patient with acute leukemia has no symptoms or has normal blood work even a few weeks or months before the diagnosis.
But in some patients, the leukemia stays in the bone marrow and is not found in blood. In that case, flow cytometry may be performed on bone marrow (usually taken from the hip bone) or other tissue, such as a piece of a lymph node.
If this disease is left untreated, a person with leukemia becomes increasingly susceptible to fatigue, excessive bleeding and infections until, finally, the body becomes virtually defenseless, making every minor injury or infection very serious. Leukemia may be fatal.
Age-specific incidence rates fall gradually from age 0-4 and remain stable throughout childhood and early adulthood, rates rise sharply from around age 55-59. The highest rates are in in the 85 to 89 age group for females and males. Incidence rates are significantly lower in females than males in most age groups.
Your doctor will conduct a complete blood count (CBC) to determine if you have leukemia. This test may reveal if you have leukemic cells. Abnormal levels of white blood cells and abnormally low red blood cell or platelet counts can also indicate leukemia.
The slow-growing form of chronic lymphocytic leukemia (CLL) is the least serious type of leukemia. It is a disease of older people; the average age at diagnosis is around 71. CLL is a malignancy of mature lymphocytes, which usually grow and divide slowly, resulting in a slowly progressive disease.
There are currently no at-home tests that a person may use to aid leukemia diagnosis. If an individual has concerns about their health, they should contact a doctor as soon as possible.
Leukemia starts in the soft, inner part of the bones (bone marrow), but often moves quickly into the blood. It can then spread to other parts of the body, such as the lymph nodes, spleen, liver, central nervous system and other organs.
Stage 1 – A patient has high levels of white blood cells and enlarged lymph nodes. Stage 2 – A patient has high levels of white blood cells and is anemic. He or she may also have enlarged lymph nodes. Stage 3 – A patient has high levels of white blood cells and is anemic.
While the exact cause of leukemia—or any cancer, for that matter—is unknown, there are several risk factors that have been identified, such as radiation exposure, previous cancer treatment and being over the age of 65.
About 1.5% of people in the United States—almost 5 million—will be diagnosed with leukemia in their lifetime. Although there are several risk factors for the disease, it is strongly related to age.
If caught early, leukemia can be cured by undergoing several cancer treatments.
Leukemia can produce a variety of symptoms, although most are not often apparent in the earliest stages of the malignancy. The most common symptoms of leukemia—fatigue, pale skin, weight loss and night sweats—are often attributed to other less serious conditions, such as the flu.
Understanding your blood count test results
If you have leukemia, your blood cells count will likely show higher than usual levels of white blood cells, which include leukemic cells. You may also have lower than usual red blood cell and platelet cell counts. If all three types are low, this is known as pancytopenia.
Often referred to as a “silent disease,” CLL can be difficult to diagnose, because people often don't have any symptoms until later in the disease, and others have symptoms that resemble signs of other conditions, such as a cold.
Chronic leukemia involves more-mature blood cells. These blood cells replicate or accumulate more slowly and can function normally for a period of time. Some forms of chronic leukemia initially produce no early symptoms and can go unnoticed or undiagnosed for years.