"Alcohol-related liver cirrhosis used to be considered a disease that would happen after 30 years of heavy alcohol consumption," Shah says. "But this study is showing that these problems are actually occurring in individuals in their 20s and 30s."
While those in their 20s and 30s often believe that only older people develop drinking-related liver problems, an alarming rise in the number of young people diagnosed with liver disease proves otherwise.
“The scary thing is that they're only in their 30s and 40s,” he says, noting that the chances of developing liver disease go up the longer a person has been drinking and is most common between the ages of 40 and 50. Other Yale Medicine doctors have diagnosed people with liver disease when they are still in their 20s.
The most common causes of cirrhosis of the liver are: Alcohol use disorder (alcohol-related liver disease) caused by long-term [chronic] use of alcohol. Chronic viral infections of the liver (hepatitis B and hepatitis C). Fatty liver associated with obesity and diabetes, but not alcohol.
Most people with cirrhosis that's found in its early stage can live healthy lives. If you are obese or have diabetes, losing weight and controlling your blood sugar can lessen damage caused by fatty liver disease.
When symptoms do occur, they may first include fatigue, weakness and weight loss, nausea, bruising or bleeding easily, swelling in your legs, feet or ankles, itchy skin, redness on the palms of your hands, and spider-like blood vessels on your skin.
Often, cirrhosis is first detected through a routine blood test or checkup. To help confirm a diagnosis, a combination of laboratory and imaging tests is usually done.
Myth: I don't have any symptoms so there's no way I could have cirrhosis. Fact: It is possible to have cirrhosis of the liver and not know it. Many patients who have cirrhosis still have enough liver function to support their body's daily operations and have no symptoms.
According to some reports, cirrhosis does not develop below a lifetime alcohol consumption of 100 kg of undiluted alcohol[8]. This amount corresponds to an average daily intake of 30 grams of undiluted alcohol for 10 years.
In a large European study enrolling patients with different stages of ALD, an intake of 400 g ethanol/week strongly increased the risk of developing cirrhosis (30%) during follow-up (3).
Alcohol-related cirrhosis usually develops after 10 or more years of heavy drinking. Women who drink heavily are more likely to get liver damage than men, partly because of their different size and build.
Symptoms of alcoholic liver cirrhosis typically develop when a person is between the ages of 30 and 40. Your body will be able to compensate for your liver's limited function in the early stages of the disease. As the disease progresses, symptoms will become more noticeable.
The disease is common in people between 40 and 50 years of age. Men are more likely to have this problem. However, women may develop the disease after less exposure to alcohol than men. Some people may have an inherited risk for the disease.
Tests to confirm a diagnosis of cirrhosis include a complete blood count (CBC), liver enzyme, liver function and electrolyte testing as well as screening for other health conditions such as hepatitis B and C viruses, liver cancer or gallstones. In most cases, a liver biopsy is used to confirm the diagnosis.
Nausea. Vomiting. A general sense of feeling unwell (malaise) Disorientation or confusion.
Cirrhosis can be diagnosed by radiology testing such as computed tomography (CT), ultrasound or magnetic resonance imaging (MRI) or via a needle biopsy of the liver. A new imaging technique called elastography, which can be performed with ultrasound or MRI, can also diagnosis cirrhosis.
Blood tests used to assess the liver are known as liver function tests. But liver function tests can be normal at many stages of liver disease. Blood tests can also detect if you have low levels of certain substances, such as a protein called serum albumin, which is made by the liver.
Depending on the cause, cirrhosis can develop over months or years. There is no cure. Treatment aims to halt liver damage, manage the symptoms and reduce the risk of complications, such as diabetes, osteoporosis (brittle bones), liver cancer and liver failure.
Cirrhosis cannot usually be cured, but there are ways to manage the symptoms and any complications, and stop the condition getting worse.
The cirrhosis is still reversible during this stage, but not enough liver tissue has been damaged to produce obvious symptoms of disease. Patients with stage 1 cirrhosis have a 99% 1-year survival rate.
Cirrhosis is a stage of ARLD where the liver has become significantly scarred. Even at this stage, there may not be any obvious symptoms. It's generally not reversible, but stopping drinking alcohol immediately can prevent further damage and significantly increase your life expectancy.
The liver is known as a silent organ, as even when a liver failure occurs, the symptoms often go unnoticed. When symptoms such as jaundice become apparent, the disorder will have already reached an advanced stage. When liver function declines, your body will feel sluggish; you will feel tired and lose your appetite.