1 Muzan (Demon Slayer) Without that antidote, it would have been impossible to kill him. So despite all her strength and humanity, Nezuko would have easily lost to Muzan.
Muzan, the King of Demons, is the strongest and also the primal demon in the world of Demon Slayer. Consuming his blood is enough to turn you into a powerful demon. He can control all the demons in existence, with only people with strong willpower like Nezuko being an exception.
1 Yoriichi Tsugikuni (Demon Slayer)
Yoriichi's mastery of the Sun Breathing technique, combined with his incredible speed and agility, made him a formidable opponent for Muzan.
In conclusion, Nezuko cannot beat Akaza in Demon Slayer. In terms of power, physical abilities, regeneration rate and overall combat ability, Akaza is far superior compared to Nezuko.
Although Gyutaro might be far stronger, Nezuko would only have to keep up against the demon until sunrise. Her Blood Demon Art is such that it only affects demons, which means there is a very good possibility for her to beat the Upper Moon 6 demons.
Giyu is one of the legendary Hashira, and he's brought down demons far more powerful than Nezuko. With his level of skill and impressive agility, he'd easily defeat Tanjiro's little sister. In fact, when Giyu first meets Tanjiro and Nezuko, he almost does kill the latter.
The warrior Muzan feared was a swordsman named Yoriichi Tsugikuni. Yoriichi was the only slayer before Tanjiro who came close to killing Muzan, and the flashback of their fight occurred in Chapter 187.
Muzan Kibutsuji was born during the Heian Era of ancient Japan to a noble family. Ever since he was in his mother's womb, Muzan was extremely frail and weak.
Muzan can detect the locations of his demons and can also read their thoughts. However, Nezuko and Tamayo are the only exceptions in the entirety of Demon Slayer, over whom Muzan has no control.
To conclude, Nezuko is a formidable powerhouse within the anime and is probably one of the strongest main characters in the series.
Nezuko, also a part of our strongest characters in the Demon Slayer list, is one of the most powerful female characters in the anime. Just by being a demon, she is more powerful than all the human characters in the series. And she is also the only demon who can withstand the sun, making her practically unkillable.
Weaknesses: Wisteria flowers are poisonous to her. Exposure to sunlight used to be lethal, but no longer affects her. Notable Attacks/Techniques: Blood Demon Art: Blood Burst: Nezuko ignites her blood and turns them into flames that only burn demons and their blood demon arts.
As Muzan is responsible for the death of her family, Nezuko hates him very much, and this hatred serves as fuel during her battles. Because of her unique abilities, she becomes sought after by Muzan, who hopes that by eating her, he will gain her immunity to the sun.
At the very beginning of the story, Muzan tried to turn Nezuko and the entire Kamado Family into Demons, however all of them failed to survive the transformation, except for Nezuko. He soon found her to be a defiant nuisance much like Tamayo, able to escape his curse and become uncontrollable.
Thus, Muzan created demons for hundreds of years even when he didn't want to turn someone. Since he didn't know anything about the Blue Spider Lily medicine, he needed others to find the plant for him by happenstance. This is the general reason why Muzan turned Nezuko into a demon.
After he neutralizes Tamayo's poison and emerges from his flesh cocoon, Muzan's hair grows in length and turns white due to Shinobu's poison accelerating his age. He also grows numerous mouths all over his limbs, each one lined with a set of incredibly sharp fangs.
Kibutsuji Muzan, Demon Slayer's King of Demons, has few weaknesses, but he still must hide from the sun. For the centuries he has been alive, Muzan's goal is to concur death and live eternally. Muzan has gained powers during this long journey: the demon curse or Muzan's curse.
Does Muzan have a favorite demon? Despite the fact that Muzan. is always shown to have disdain for his creations, Muzan does in fact have a favorite. On that list is Naki, made due to a convenient blood demon.
Akaza is an upper-rank-three Demon and one of the most faithful minions of the Demon king Muzan Kibutsuji.
Apart from that, Muzan doesn't hate Akaza because of his obedience. The only Demon he despises the most is the Upper Rank Two: Doma.
Tanjiro's connection to Yoriichi is not through blood relation, but through their similar appearances, which is due to the divine nature of Sun Breathing. (Also Read: Did Demon Slayer hire a Bollywood director for Season 3? Fans speculate!)
Sanemi Shinazugawa
In their initial encounter, Sanemi held a deep hatred towards Nezuko due to her nature as a demon.
In his first appearance, the Wind Hashira Sanemi Shinazugawa discovered Nezuko Kamado and tried to agitate her by stabbing her repeatedly. When that didn't work, he cut his arm in an attempt to get her to bite him and prove she was no different than any other demon, ignoring Tanjiro's pleas for him to stop.
The “Swordsmith Village” arc ended with the major reveal that Nezuko, unlike every other demon, can't be killed by sunlight, which then put her at the center of the final arc due to Muzan wanting to eat her to obtain that same immunity and become truly immortal.