Nearly half of patients on all types of monoaminergic antidepressants report emotional blunting,6 and it is associated with serotonin reuptake inhibitor (SSRI) therapy as follows: among 161 patients, 46% reported a narrowed range of affect, 21% reported an inability to cry, and 19% reported apathy.
One study of 595 patients found that antidepressant use was associated with an increased risk of cognitive decline over 4.5 years among depressed patients without cognitive impairment.
If you have a form of anxiety or phobia, an antidepressant could help you feel calmer and more able to deal with other problems. It could also help you feel more able to benefit from other anxiety treatments, such as cognitive behavioural therapy (CBT).
When first starting antidepressants, you may suddenly find that you don't feel like yourself anymore. Though your depression symptoms may have improved, the overwhelming waves of gloom can sometimes be replaced by an emotional inertness in which are neither able to cry nor share a real belly laugh.
Antidepressants and dulled emotions
Doctors typically treat MDD with antidepressants like selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs). A 2017 survey reported that 46% of people on antidepressants experienced symptoms of emotional numbness.
Emotional blunting is frequently reported by patients with major depressive disorder (MDD) and has been identified as one of the most prominent side effects of antidepressants leading to medication discontinuation.
When first starting antidepressants, some people have mild stomach upset, headache or fatigue, but these side effects often diminish in the first few weeks as the body adjusts. Some people gain weight, though many stay “weight neutral,” and some even lose weight, Dr. Cox says.
When the researchers looked at all the study participants, they found that those taking SSRIs were more likely to say they felt less at ease with sharing their partners' thoughts and feelings, and less wishful that their love for their partner would last forever since they started taking their medication, compared with ...
Depersonalisation and derealisation are relatively common on antidepressants.
The majority of people taking the most commonly prescribed antidepressants—selective serotonin reuptake inhibitors (SSRIs)—improve substantially. But sometimes, SSRIs go beyond improving mood and make a person feel too little emotion.
Antidepressants reduce symptoms of depression by balancing chemicals in the brain called neurotransmitters, which affect mood and emotions, particularly dopamine and serotonin. These depression medications can improve your mood, concentration, sleep, and increase your appetite.
Some antidepressants can also cause feelings of agitation, restlessness and detachment. These feelings may resemble symptoms of anxiety and may add to, rather than relieve, feelings of hopelessness and despair. Some people may become suicidal or violent.
If the symptoms develop later or gradually, they may constitute a relapse of the depression. Ultimately, these withdrawal symptoms will improve with time, but they can be unpleasant for days and possibly even weeks. In time, the brain readjusts and people should experience a return to their normal state.
While antidepressants are generally intended to help with brain fog, some can cause brain fog as a side effect, depending on the medication and your unique response to it. Sedatives, pain medicine, bladder control medicine and antihistamines are some of the other types of medications that can lead to brain fog.
In other words, antidepressants are effective against chronic, moderate and severe depression. They don't help in mild depression. The various antidepressants have been compared in many studies. Overall, the commonly used tricyclic antidepressants (SSRIs and SNRIs) were found to be equally effective.
Common side effects of selective serotonin reuptake inhibitors (SSRIs) and serotonin-noradrenaline reuptake inhibitors (SNRIs) can include: feeling agitated, shaky or anxious. feeling and being sick.
Selective serotonin reuptake inhibitors (SSRIs), commonly used to treat depression, are associated with loss of motivation, anergy, and lack of curiosity often referred collectively as apathy.
Depersonalization symptoms
Feeling like a robot or that you're not in control of your speech or movements. The sense that your body, legs or arms appear distorted, enlarged or shrunken, or that your head is wrapped in cotton. Emotional or physical numbness of your senses or responses to the world around you.
Today millions of people take serotonin-enhancing antidepressants. These medications cause emotional blunting and dysfunction in sexual desire, arousal and orgasm in both men and women. We propose that these antidepressants have other side effects, due to their impact on several related neural mechanisms.
How do I know if my antidepressant works? When you start taking an antidepressant, you should begin to function better in your daily life before you start feeling better, says Dr. Michael McGee. In other words, you should begin sleeping better, eating better, and having more energy.
Avoid caffeine, tobacco and alcohol. Drink plenty of fluids. Take your antidepressant at bedtime if your doctor approves.
The people we spoke to initially experienced insomnia, feeling lethargic and sleepy, dizziness, headaches, vivid dreams, dry mouth or bad taste in the mouth, sickness or nausea, hallucinations, loss of appetite, sweating, memory problems.
Summary: Antidepressants for major depressive disorder reduce the aversive response triggered by exposure to the suffering of others. Findings suggest antidepressants may lead to impaired empathy of pain perception.
It's usually recommended that a course of antidepressants continues for at least 6 months after you feel better, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely.
Specifically, weight gain seems to be a common long-term risk, especially the medications that affect serotonin levels. This could be due to the fact that serotonin is associated with an increase in appetite. There is also a risk of higher blood sugar levels and diabetes with taking antidepressants long-term.