The pair were first seen on screen together as sparring psychiatrists on NBC's Cheers starting in 1986, when Neuwirth joined as Lilith Sternin. Amid an endless back-and-forth of barbed comments, Lilith eventually married Grammer's Frasier Crane, and they welcomed son Frederick late in the show.
In the Cheers episode "The Stork Brings a Crane," Lilith gives birth to her and Frasier's son, Frederick in the back of taxi (though the birth happens off-screen).
Several months later, Lilith meets Frasier again and with some help from Frasier's ex-fiancée Diane Chambers (Shelley Long), they start a romantic relationship, eventually living together, marrying, and having a son, Frederick.
Early in Cheers' final season, Lilith has an affair with a colleague of hers. She leaves Frasier & they officially seperate. After several months & a failed science experiment, Lilith leaves her lover to come home and be with Frasier again. Frasier had moved on.
The baby that Niles and Daphne have at the end of the show is not a result of a real life pregnancy of Jane Leeves, the actress who plays Daphne. However, she was pregnant earlier in the show. In season 8 the actress got pregnant and it was simply written into the show as a weight gain.
"Freddy" made his first appearance as a baby on Cheers, while his parents were still married; he appears in several episodes throughout the show's run.
Niles and Lilith sleep together, effectively ending Frasier and Lilith's post-divorce liaisons. The celebrity caller in this episode is Halle Berry (Betsy) whose husband wants to take her on an anniversary cruise, but she has recurring nightmares about being shipwrecked.
Early in the fifth season, Roz discovers that she is pregnant with the child of a 20-year-old college student with whom she had a brief fling.
This was primarily because they didn't want viewers to think that Frasier was simply riffing off with what Cheers did with Vera, Norm's (George Wendt) wife, who was often mentioned but never made it on screen. They planned on debuting Maris in episode 3, but the gag became too funny that they stuck with it.
'Frasier' was not only one of the best sitcoms ever made, but it had a perfectly sweet series finale.
Dr. Melinda "Mel" Karnofsky Crane (Jane Adams) is Maris Crane's plastic surgeon, and for a period, Niles Crane's girlfriend and wife. She is fussy, neurotic, and fastidious, much like Niles.
Jane Leeves was pregnant twice during Frasier. While her second pregnancy was written into the final season, her first wasn't and the writers gave Daphne a storyline where she gains weight instead.
"Frasier" Room Service (TV Episode 1998) - Plot - IMDb.
Rather than tell him she can't see a future for them, she pretends to be married to Niles. Daphne's ex-fiancé Clive visits her in Seattle to declare that he still loves her. Rather than tell him she can't see a future for them, she pretends to be married to Niles.
Nanette Guzman (portrayed by Emma Thompson on Cheers) is the first wife of Frasier Crane. He married her when he was 20. They were both hippies and wrote poetry and music together. They divorced long before he moved to Boston, and lost touch.
By the end of the season, Roz gives birth to her new baby girl, whom she names Alice May Doyle. Late in the series, Roz finally manages to maintain a seemingly stable relationship with Roger, a garbageman.
The pair never got together because Frasier and Roz were fundamentally different people with radically opposite interests. Frasier delighted in the high-society pursuits of opera and great literature, while Roz partook in the less sophisticated pastimes of bars and Bruce Springsteen concerts.
The Daphne-Niles Relationship is the romantic relationship between Niles Crane and Daphne Moon. They are now married and have 1 child.
Lilith is an immortal who had lived in the city of pre-Cataclysm Atlantis, one of its few survivors. Over the centuries, she gave birth to many of her children – (the Lilin) – including Creed, Pilgrim, Fang, Doc, Meatmarket, Skinner, and Nakota.
Daphne reveals that she knows about Niles' seven-year crush on her. She has tormented herself about her own feelings towards Niles and believes that she has fallen in love with him in return.
Niles's first wife is Maris Crane, the haughty, anorexic daughter of a wealthy Seattle family, who is never seen on the show, despite being referred to in nearly every episode during his relationship with her. Season 1 references that Niles married for money.
Charlotte Connor (Laura Linney) is a matchmaker recently arrived from Chicago and Frasier's final love interest on the series.
A giddy Frasier (Kelsey Grammer) mistakenly believes he's the object of a secret female admirer's affection, and even though he's squiring around an attractive new woman (guest star Grace Phillips) who adores him, he sneakily rings up every number in his little black book hoping to double his pleasure.
In the first episode of Season 10, Daphne and Niles marry in a small, private ceremony in Reno, Nevada.