Some people need to keep taking it long term. If you have only had one psychotic episode and you have recovered well, you would normally need to continue treatment for 1–2 years after recovery. If you have another psychotic episode, you may need to take antipsychotic medication for longer, up to 5 years.
Previous studies found that the death rate among people with schizophrenia on antipsychotic medications was 30%-50% lower than among those who took a placebo. But most of the studies were shorter than six months, which does not reflect the fact that antipsychotic treatment is often lifelong, the study authors noted.
Consensus guidelines typically recommend continued antipsychotic medication for 1–2 years, although it has been suggested that treatment discontinuation in the form of targeted intermittent treatment (dose reduction, antipsychotic discontinuation if feasible, and immediate reintroduction if symptoms reemerge) should ...
Prolonged use of antipsychotic medications is viewed as a key factor in treatment for schizophrenia, but there is very little systematic evidence for the long-term benefits of antipsychotics. There is even some longitudinal data suggesting the opposite.
After a first episode of psychosis in schizophrenia and related disorders, stopping antipsychotics is considered when the patient has made a full recovery and been well for at least 12 months.
For neurological, neuropsychological, neurophysiological, and metabolic abnormalities of cerebral function, in fact, there is evidence suggesting that antipsychotic medications decrease the abnormalities and return the brain to more normal function.
But with the right treatment, most people can live complete and fulfilling lives – thanks mainly to their antipsychotic medication. But of course, all medications have side-effects and for some people on antipsychotics these side-effects can range from mildly debilitating to life threatening.
you have the right to refuse a medication or to stop taking it, even if your doctor thinks this might make your mental health problem worse.
Some people may be able to stop taking antipsychotics without problems, but others can find it very difficult. If you have been taking them for some time, it can be more difficult to come off them. This is especially if you have been taking them for one year or longer.
Previous research has also shown that the use of antipsychotics may raise the risk of metabolic syndrome in patients with schizophrenia. Metabolic syndrome has, in turn, been associated with heart disease and diabetes.
Antipsychotics can help manage your symptoms of psychosis. This can help you feel more in control of your life, particularly if you are finding the psychotic symptoms distressing. Research suggests 4 out of 5 people with severe mental illness, who take antipsychotics, find they're successful in treating their symptoms.
Taking antipsychotics can increase your risk of developing metabolic syndrome. If you experiencing metabolic syndrome, this means you are at higher risk of developing: diabetes. stroke.
For people with schizophrenia, long-term antipsychotic use is usually accompanied by adverse effects such as weight gain, metabolic syndrome, diabetes, and ischemic heart disease, demonstrating their important role in increased mortality.
Antipsychotic medications improve the quality of life for most, but not all, patients with chronic schizophrenia, and most of them will require medications for many years-even for life.
When you introduce the drug to your body, your body compensates, and you see tolerance gradually over time. But this is not the case when medications work for prolonged periods of time such as months, or years, and then spontaneously stop working.
They can cause movement disorders such as twitching and restlessness, sedation and weight gain, and lead to diabetes. Because of these side effects, antipsychotic drugs are usually only used to treat severe mental illnesses such as schizophrenia or bipolar disorder.
However, some patients are able to sustain a psychosis-free existence after the cessation of antipsychotics. Several studies show that only 25%–55% of patients with schizophrenia who stopped taking antipsychotic medication experienced the relapse of symptoms in the first 6 to 10 months after they stopped taking them.
You may find it's possible to manage your symptoms, or to make a full recovery, without medication. If you are taking antipsychotics, you may also want to use other options to support your mental health, as well as your medication.
The reasons people gave for discontinuing their meds included fear of health risks and side effects of long-term use. I am also aware that often psychiatrists offer drugs too quickly, and without also strongly advising the patient concurrently do therapy to help deal with emotional issues.
Evidence of the rapidity at which antipsychotics can affect brain volume in humans was recently provided by Tost and associates. These investigators found a significant, reversible decrease in striatal volume in healthy subjects within 2 hours after they were treated intravenously with haloperidol.
Clozapine and olanzapine have the safest therapeutic effect, while the side effect of neutropenia must be controlled by 3 weekly blood controls.
Meyer-Lindberg himself published a study last year showing that antipsychotics cause quickly reversible changes in brain volume that do not reflect permanent loss of neurons (see 'Antipsychotic deflates the brain')7.
Results: Antipsychotics, as a group, increase weight and may lead to dry mouth and bad breath, cataracts, hirsutism, acne, and voice changes; they may disturb symmetry of gait and heighten the risk for tics and spasms and incontinence, potentially undermining a person's attractiveness.
Antipsychotic medications can help to calm and clear confusion in a person with acute psychosis within hours or days, but they can take up to four or six weeks to reach their full effect.
Of the atypical antipsychotics, risperidone is the weakest in terms of atypicality criteria.