Diuretics and betahistine. These medicines can be used together or alone to improve vertigo. Diuretics lower how much fluid is in the body, which may lower the amount of extra fluid in the inner ear. Betahistines ease vertigo symptoms by improving blood flow to the inner ear.
Betahistine acts on histamine receptors and also increases the activity of histamine. These actions improve the blood flow in the inner ear and this helps reduce the pressure of the fluid that fills the labyrinth in the inner ear.
Salt restriction and diuretics.
Limiting dietary salt and taking diuretics (water pills) help some people control dizziness by reducing the amount of fluid the body retains, which may help lower fluid volume and pressure in the inner ear.
Betahistine is a medicine used to treat the symptoms of Ménière's disease. These symptoms include: feeling dizzy and a spinning sensation (vertigo) ringing in the ears (tinnitus)
Medicinal Benefits
BETAHISTINE is indicated to treat symptoms such as ringing in your ears (tinnitus), dizziness, vertigo, loss of balance, and hearing loss associated with Meniere's disease. BETAHISTINE works by increasing the blood flow to your brain and by lowering the extra pressure build up in the inner ear.
How long does it take to work? When you start taking betahistine, it may take a couple of weeks before you notice any improvements. Even when you start feeling better, your doctor may want you to carry on taking the tablets for some time, to stop your symptoms from coming back.
About betahistine
It typically causes attacks of dizziness with a spinning sensation (vertigo), hearing loss and noises in the ear (tinnitus). The attacks can vary in severity, and in how often they occur.
Taking too much betahistine can make you feel sick or sleepy, or give you stomach ache.
Swallow the tablets with water. Take the tablet with or after a meal. However, Betahistine can cause mild stomach problems (listed in Section 4). Taking Betahistine with food can help reduce stomach problems.
Popping your ears can help open the eustachian tube, allowing fluid to drain. The simplest way to pop your ears is to yawn, chew, or swallow. You may also want to try popping your ears using something called the Valsalva maneuver: Take a deep breath and hold it.
Your ear may also feel blocked and uncomfortable, with a sense of fullness. Some people may also experience sensitivity to sound. Attacks of vertigo at this stage can last from 20 minutes to 24 hours, but usually last around two to three hours.
Four distinct patterns of Eustachian tube behaviour were seen, three of which indicated Eustachian tube dysfunction. Betahistine had no positive effect on Eustachian tube opening, although previous animal studies had suggested a beneficial effect.
Pseudoephedrine is used to relieve nasal or sinus congestion caused by the common cold, sinusitis, and hay fever and other respiratory allergies. It is also used to relieve ear congestion caused by ear inflammation or infection.
Some medicines and betahistine affect each other and can increase your chance of side effects. Tell your pharmacist or doctor if you're taking: medicines called MAO inhibitors, used to treat depression or Parkinson's disease. antihistamines for allergies such as hay fever.
Your doctor may advise you to try betahistine for 6 to 12 months to see if it helps to reduce your symptoms. If it does, it can then be continued.
The highest proportion of good or excellent clinical improvement scores were observed for nausea (89.9–90.2%), vomiting (82.4–82.7%) and faintness (87.9–88.2%) at end of treatment.
Anxiety symptoms
The repeated-measures ANOVA showed a significant effect of time (P<0.00001), indicating that both high-dose and low-dose betahistine could significantly reduce the HARS score.
Do not stop taking this medicine suddenly, or change the dosage, without checking with your doctor. Do not use this medicine to treat any other complaints unless your doctor or pharmacist tells you to. Do not give this medicine to anyone else, even if they have the same condition as you.
Availability. Betahistine is widely used and available in Europe, including in the United Kingdom. It was approved by the Food and Drug Administration in the early 1970s for Ménière's disease, but approval was later withdrawn for lack of evidence of efficacy. The withdrawal was upheld by a US court of appeals in 1968.
Antihistamines, e.g. betahistine and cinnarizine. These are sedative, and patients should not operate machinery or drink alcohol.
Increases in vestibular blood flow and decreases in blood pressure were observed in response to betahistine infusions.
Taking the drug betahistine could reduce the feeling of vertigo, even when the cause hasn't been found. Vertigo is a feeling that the environment is moving around when it is not. It can be caused by problems in the ear or the brain.