Diazepam is also used to relax muscles and treat muscle spasms that occur due to injury and conditions like cerebral palsy and paraplegia. It can also be used to treat panic attacks as well as symptoms of alcohol withdrawal, such as trembling, confusion and anxiety.
Diazepam is used to treat anxiety, muscle spasms and fits (seizures), such as epilepsy. It belongs to a group of medicines called benzodiazepines. It is available only on prescription. Diazepam is also used to treat alcohol withdrawal symptoms, such as sweating or difficulty sleeping.
Oxazepam and diazepam
Benzodiazepine medications like oxazepam (Serax, Zaxopam) and diazepam (Valium) are anti-anxiety medications. They are sometimes prescribed as muscle relaxants. But these really aren't recommended because they don't work well, are sedating, and can be habit-forming.
muscle spasms – you should begin to feel less pain after 15 minutes. Your muscles will start to relax when you have been taking diazepam regularly for a few days.
Diazepam exhibits various effects on motor nerves and skeletal muscle: 1. The maximum conduction velocity is decreased, 2. the duration of the negative component of the muscle action potential is increased, 3. the latency between the electrical and the mechanical response is increased, 4.
Diazepam improves the effect of a chemical in the brain called gamma-aminobutyric acid (GABA). GABA is a chemical whose transmission across nerves in the brain is known to produce a 'calming effect'.
Valium (diazepam) is a medication that can be used to treat anxiety as well as alcohol withdrawal and seizures. Valium also has a sedative effect that is useful for treating muscle spasms. Valium for anxiety works by calming the brain and nerves.
Other important side effects include: Paradoxical reactions with excitability. Muscle spasm. Lack of sleep.
anxiety – 2mg, taken 3 times a day, this can be increased to 5mg to 10mg, taken 3 times a day. sleep problems (related to anxiety) – 5mg to 15mg, taken once a day at bedtime. muscle spasms in adults – 2mg to 15 mg a day.
Drowsiness, dizziness, tiredness, blurred vision, or unsteadiness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.
drowsy or sedating antihistamines, such as chlorphenamine or promethazine. strong painkillers, such as codeine, methadone, morphine, oxycodone, pethidine or tramadol. HIV medicines, such as ritonavir, atazanavir, efavirenz or saquinavir. antifungal medicines, such as fluconazole.
Benzodiazepines are a group of medications that can help reduce anxiety and make it easier to sleep. They are also used as a muscle relaxant, to induce sedation for surgery and other medical procedures, and in the treatment of seizures and alcohol withdrawal.
The results of the study revealed that, diazepam (prototype benzodiazepine agonist) has a significant anti-inflammatory effect on the different experimental models of inflammation whether, acute or chronic.
Sometimes, muscle relaxants such as Soma (carisoprodol), Flexeril (cyclobenzaprine), and Valium (diazepam) are used to treat neck pain. These are also sometimes combined with another medicine, such as in Norgesic, which combines orphenadrine with aspirin and caffeine.
The increased dopamine acts on specialized receptors on the nucleus accumbens neurons (D1 dopaminergic receptors), and activates them. These in turn trigger a biochemical cascade that increases the activity and energy output of the neurons' mitochondria — the cell's powerhouses.
For anxiety: Adults—2 to 10 milligrams (mg) 2 to 4 times a day. Older adults—At first, 2 to 2.5 mg 1 or 2 times a day. Your doctor may increase your dose if needed.
Diazepam reduces both arterial blood pressure and muscle sympathetic nerve activity in human.
Response and effectiveness
The peak effects of diazepam are seen within 1 to 1.5 hours in most people. Diazepam is metabolized to active metabolites and its effects may last for more than 24 hours and extend with repeated dosing as the drug accumulates in the body.
Depending on a number of factors, this time period can last 30-56 hours. It therefore takes an average of 10 days for the entirety of the drug to leave the system, and that's just for the drug itself.
Valium, a drug from the benzodiazepine family, has powerful effects on the central nervous system, suppressing these abnormal electrical signals in the brain and nerves.
Succinylcholine. Succinylcholine is the only depolarizing muscle relaxant.
No muscle relaxers are available over the counter in the U.S., but some OTC medications can have muscle-relaxing effects. These include guaifenesin and NSAIDs like ibuprofen and naproxen.