The Estrogen Decline Causes Neuroinflammation Through Producing Magnesium Deficiency in Ovariectomized and Aged Female Mice. Clinical data show that serum Mg2+ is decreased in postmenopausal women.
Summary. Magnesium is a critical mineral in the health of every human, but people may notice the effects of a decline of this substance in menopause. Magnesium typically decreases along with estrogen in menopause, making symptoms associated with low magnesium levels more noticeable.
Hormone creation – magnesium actually makes your hormones progesterone, estrogen and testosterone, so if you're getting into peri-menopause or just off the Pill and your levels are low, it can be your best friend.
Several hormones including PTH, antidiuretic hormone (ADH), calcitonin, glucagon and insulin have been shown to affect magnesium reabsorption. Of these, PTH is the most important.
Magnesium deficiency in healthy people is rare but it can be caused by: a poor diet (especially in elderly people or those who don't have enough to eat) type 2 diabetes. digestive problems such as Crohn's disease.
Thus, the elderly population is especially at risk of magnesium deficiency due to low intake but also increased risk for chronic diseases that predispose to magnesium deficiency (ageing also reduces magnesium absorption from the diet, ie, achlorhydria).
Deficiencies due to poor absorption of magnesium from the gastrointestinal tract include: Diseases causing malabsorption such as celiac disease and inflammatory bowel disease. Gastric bypass surgery. Hereditary syndromes causing poor absorption of magnesium (primary intestinal hypomagnesemia).
Hormone creation - magnesium actually makes your hormones progesterone, estrogen and testosterone, so if you're getting into perimenopause or are just off the Pill and your levels are low, it can be your best friend.
No interactions were found between Estradiol Patch and magnesium oxide.
Magnesium Glycinate: great for calming, helping with sleep and hormone balance.
I most often recommend magnesium glycinate or bis-glycinate. This form of magnesium has an affinity for nervous tissue, is highly absorbable and is very well tolerated. It has the least laxative effect of all forms of magnesium.
To increase your estrogen levels, consider adding: Boron, a mineral that helps your body absorb testosterone and estrogen. Vitamin B, which helps your body create and use estrogen. Vitamin D, which functions as a hormone in the body and helps with estrogen production.
Magnesium is important for healthy bones. People with higher intakes of magnesium have a higher bone mineral density, which is important in reducing the risk of bone fractures and osteoporosis. Getting more magnesium from foods or dietary supplements might help older women improve their bone mineral density.
The use of chemicals, such as fluoride and chlorine, bind to magnesium, making the water supply low in the mineral, as well. Common substances — such as sugar and caffeine — deplete the body's magnesium levels.
One study found that very high doses of zinc from supplements (142 mg/day) can interfere with magnesium absorption and disrupt the magnesium balance in the body [17].
Mg is essential in the metabolism of vitamin D, and taking large doses of vitamin D can induce severe depletion of Mg. Adequate magnesium supplementation should be considered as an important aspect of vitamin D therapy.
Research indicates a strong link between low magnesium levels and a number of autoimmune diseases ranging from Alzheimer's to Diabetes. In fact, there is a significant correlation between increasing dietary magnesium to reduce the severity of rheumatoid and psoriatic arthritis.
Chronic magnesium deficiency is often associated with normal serum magnesium despite deficiency in cells and in bone; the response to oral supplementation is slow and may take up to 40 weeks to reach a steady state.
Personality changes, including apathy, depression, agitation, confusion, anxiety, and delirium are observed when there is a deficiency of this element. Rodents receiving a diet deficient in magnesium displayed depressive behaviour that was reversed by antidepressant drugs.