SLE and other autoimmune disorders tend to run in families, but the inheritance pattern is usually unknown. People may inherit a gene variation that increases or decreases the risk of SLE, but in most cases do not inherit the condition itself.
Lupus is not a hereditary condition.
In 20% of people who have lupus, a parent or sibling already has lupus or develops it later. About 5% of children born to a parent with lupus will develop the disease. Even in people with no lupus in their family history, other autoimmune diseases are more likely.
Although lupus can develop in people with no family history of lupus, there are often other autoimmune diseases in some family members. People of African, Asian, Pacific Island, Hispanic/Latino, Native American or Native Hawaiian descent have a greater risk of developing lupus, which may be related to genes.
Symptoms and diagnosis occur most often between the ages of 15 and 44. Symptoms of lupus will occur before age 18 in only 15 percent of the people who are later diagnosed with the disease.
Systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS) may coexist, and they are chronic complex disorders, with an autoimmune background, multifactorial etiology, multiple circulating autoantibodies, and variable prognosis.
With close follow-up and treatment, 80-90% of people with lupus can expect to live a normal life span. It is true that medical science has not yet developed a method for curing lupus, and some people do die from the disease. However, for the majority of people living with the disease today, it will not be fatal.
Common symptoms include fatigue, hair loss, sun sensitivity, painful and swollen joints, unexplained fever, skin rashes, and kidney problems. There is no one test for SLE. Usually, your doctor will ask you about your family and personal medical history and your symptoms. Your doctor will also do some laboratory tests.
The symptoms may also appear suddenly or gradually. Many people with lupus do not receive a diagnosis straight away because it can mimic other conditions, including fibromyalgia, rheumatoid arthritis, and various others that affect the same organ systems.
Lupus is a chronic inflammatory autoimmune disease with a wide range of clinical presentations resulting from its effect on multiple organ systems. There are four main types of lupus: neonatal, discoid, drug-induced, and systemic lupus erythematosus (SLE), the type that affects the majority of patients.
With age, symptom activity with lupus often declines, but symptoms you already have may grow more severe. The accumulation of damage over years may result in the need for joint replacements or other treatments.
Although doctors haven't proven that stress is a direct cause of lupus, it's known to trigger flare-ups in people who already have the disease. Stressful events that can make symptoms worse include: A death in the family. Divorce.
Prevention Tips
Exposure to UV rays from sunlight and other light sources can trigger flares in many people with lupus. Staying out of the sun between 10 a.m. and 4 p.m., applying sunscreen every day, and wearing sun-protective clothing can prevent UV rays from triggering a lupus flare.
The most common response given is that people feel fatigue as a heaviness. It feels like there is a weight constantly pushing down on part of them or on their entire body. With that degree of heaviness, it is much harder to find the energy to move and get things done.
Lupus symptoms can also be unclear, can come and go, and can change. On average, it takes nearly six years for people with lupus to be diagnosed, from the time they first notice their lupus symptoms.
Lupus is a lifelong disease that can affect many parts of your life. But, many women with lupus live long, healthy lives. You can take steps to control your symptoms, prevent lupus flares, and cope with the challenges of lupus.
Half of people with lupus also have kidney problems, called lupus nephritis. Symptoms include weight gain, swollen ankles, high blood pressure, and decreased kidney function.
Diagnostic Criteria. Systemic lupus erythematosus can be difficult to diagnose: no single blood or imaging test can definitively identify it, and its symptoms can be vague, progress slowly, change, or mimic other conditions, such as rheumatoid arthritis. As a result, it's important to consult a rheumatologist.
While some similarities and symptoms can overlap, MS and lupus are very different conditions. In general, a person with MS is more likely to experience neurological symptoms, such as numbness, blurred vision, and difficulty balancing. A person with lupus tends to have symptoms such as rashes and headaches.
While the environmental elements that can trigger lupus and cause flares aren't fully known, the most commonly cited are ultraviolet light (UVA and UVB); infections (including the effects of the Epstein-Barr virus), and exposure to silica dust in agricultural or industrial settings.
Many lupus patients aren't able to do intensive physical work, like waitressing or working in a grocery store. Jobs that involve standing for long periods, like working a cash register, greeting customers, or being a hostess at a restaurant, can be physically tiring as well as rough on the joints.
In MS, your own immune system attacks your nervous system by mistake and damages your nerves. In lupus, your immune system attacks healthy tissues like your skin, joints, kidneys, heart, or lungs. But it can also damage your nerves and brain. They're both more common in younger women.