Magnesium supplementation has been linked to improvements in symptoms of major depression,8 premenstrual symptoms,9 postpartum depression,8 and chronic fatigue syndrome.
Research suggests that while not all people with depression have low magnesium, those that do might be more likely to see symptom improvement with magnesium supplements. This may also suggest that getting enough magnesium in your diet can possibly help to prevent depression.
Magnesium might help. If you find yourself irritable, stressed or downright depressed, this critical mineral may help you get out of your funk. Studies suggest adequate magnesium intake can calm stress, improve mood and enhance sleep.
Generally speaking, you will find that magnesium supplements start to work after one week of using them. After one week of regular magnesium supplementation, individuals may experience benefits such as improved energy levels, reduced muscle cramps, better sleep quality, and reduced anxiety.
Stress And Anxiety Relief
Magnesium may be the “chill pill” you need. Magnesium plays a role in regulating the hypothalamic-pituitary-adrenal axis (HPA axis), our stress response system, and deficiencies in the mineral have been shown to induce anxiety and HPA axis dysregulation in an animal model.
Magnesium helps you to relax by stimulating the production of melatonin and serotonin which boost your mood and help you sleep. Magnesium also reduces the production of cytokines and cortisol, which lead to increased inflammation and stress. While it is important to consume enough magnesium, too much of it is toxic.
The good news is that some studies (study links, a and b) have identified how magnesium may ease certain symptoms of stress and anxiety. Here are the facts: Magnesium may help to control the chemical messengers (neurotransmitters) in the brain, resulting in a calming effect on the body.
"Serotonin and melatonin are crucial in determining your mood. Magnesium works as an important co-factor required for conversion of tryptophan (from proteins we get from food) to serotonin and melatonin, both of which help in falling asleep."
It blocks the activity of more stimulating neurotransmitters and binds to calming receptors, resulting in a more peaceful, resting state. It helps to regulate the release of stress hormones like cortisol, acting like the brake on your body's nervous system.
Very low magnesium levels may cause:
Headaches. Nighttime leg cramps. Numbness or tingling in the legs or hands. General body weakness.
But when should they be taken? Ideally, you should take magnesium at the same time every day, whether that's in the morning with your cup of coffee or in the evening right before you go to bed. The time of day doesn't matter so much—it's the consistency of taking magnesium daily that matters most.
The claimed benefits of magnesium supplementation range from boosts in everyday wellness — better sleep, increased energy levels and improved mood — to specific health benefits, such as lower blood pressure, reduced risk of heart disease and improvement in migraines.
Magnesium is important for many processes in the body, including regulating muscle and nerve function, blood sugar levels, and blood pressure and making protein, bone, and DNA.
One study. View Source of older adults with insomnia found that magnesium supplementation at a dose of 500 milligrams daily for eight weeks helped them fall asleep fast, stay asleep longer, reduced nighttime awakenings, and increased their levels of naturally circulating melatonin.
High doses of magnesium from supplements or medications can cause nausea, abdominal cramping and diarrhea. In addition, the magnesium in supplements can interact with some types of antibiotics and other medicines.
Magnesium supplements can cause nausea, cramps, and diarrhea. Magnesium supplements often cause softening of stool. Interactions. Magnesium supplements may interact with certain medicines, including diuretics, heart medicines, or antibiotics.
Because magnesium can help relax muscles and the brain, allowing for possibly an easier time getting to sleep. Since it can take up to 30 minutes for magnesium's effects to be seen, it's best to take it at the start of your bedtime routine. This may help with unwinding and calming the mind before bed.
Overall, if you are looking for a magnesium option that may provide the most calming and restful effect in the evening or using it for overall mood support, a magnesium glycinate may be your better option. In addition, you may see some anti-inflammatory support from the glycinate form as an added bonus!
Hall-Flavin, M.D. Vitamin B-12 and other B vitamins play a role in producing brain chemicals that affect mood and other brain functions. Low levels of B-12 and other B vitamins such as vitamin B-6 and folate may be linked to depression.