While Ozempic can be an effective treatment option for many people with diabetes, some patients have reported experiencing sleep problems while taking the medication.
Difficulty falling asleep is not a known side effect of Ozempic, so if that is what is causing your fatigue you may want to consider other reasons why that is happening. Keep in mind that as time goes on and your body adjusts to the medication, you may notice that side effects from Ozempic improve.
Does Wegovy (Semaglutide) Cause Insomnia? No, Wegovy® does not cause insomnia or difficulty sleeping.
It doesn't make a big difference whether you take it in the morning or at night. It's possible to change the day of the week you inject Ozempic. The general rule is to avoid injecting it with less than 2 days in between shots. But it's best to talk with your healthcare provider or pharmacist first.
In rare cases, the use of Ozempic may cause anxiety and mood swings, irritability, shakiness, and confusion. However, when you take other medications along with Ozempic, it may escalate anxiety or mood change.
Semaglutide (Ozempic, Wegovy, Rybelsus) can cause side effects that some people are unable to tolerate. Following dosing guidelines can help manage these side effects. Nausea, vomiting, and diarrhea are the most common semaglutide side effects.
Common Side Effects of Ozempic
“The most common side effects are gastrointestinal in nature: nausea, vomiting, diarrhea and constipation.” While the majority of people who take Ozempic will most likely experience these symptoms at some point during their treatment, they should subside over time, continues Dr. McGowan.
Does Ozempic make you feel tired? The short answer is that, yes, Ozempic can make you feel tired, but it's a rare side effect of the drug. Ozempic and its active ingredient, semaglutide, have been extensively studied for safety and efficacy for blood sugar control and weight loss.
How Long Can You Stay on Ozempic (semaglutide)? A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
“Ozempic face” is a term for common side effects of the type 2 diabetes medication semaglutide (Ozempic). It can cause sagging and aging of facial skin. A doctor may recommend lifestyle modifications or facial fillers to treat these effects.
Common causes of chronic insomnia include: Stress. Concerns about work, school, health, finances or family can keep your mind active at night, making it difficult to sleep. Stressful life events or trauma — such as the death or illness of a loved one, divorce, or a job loss — also may lead to insomnia.
The starting Ozempic dosage is usually 0.25 mg once weekly. This dose isn't intended to have an effect on your blood glucose. Instead, it's meant to help your body start adjusting to digestion-related side effects.
Besides weight loss, semaglutide can cause side effects like nausea, diarrhea, constipation, and headaches. Both Ozempic and Wegovy have been on the U.S. Food and Drug Administration (FDA) drug shortage list for months.
Stop using Ozempic® and get medical help right away if you have any symptoms of a serious allergic reaction, including swelling of your face, lips, tongue, or throat; problems breathing or swallowing; severe rash or itching; fainting or feeling dizzy; or very rapid heartbeat.
You've hit a plateau
It's normal to eventually hit a point where your weight loss slows down, especially if you're not working on keeping or building up your muscle mass. Losing muscle along with fat slows your metabolism and can slow down your weight loss.
If you stop taking Ozempic, the weight you lost will likely return, fast. People who ceased use of semaglutide gained back, on average, a full two-thirds of the weight they had lost on the drug within one year, according to an August 2022 study, the Wall Street Journal reports.
Some individuals may actually gain more weight after stopping an obesity drug than they initially lost, Conde-Knape added. Studies have similarly shown weight rebound in people who stop taking Ozempic.
Teresa Shepherd said she lost 90 pounds while taking an off-brand version of the drug Ozempic for around eight months. Shepherd, who lives in Florida, told "Good Morning America" she has been able to maintain her weight loss two months after stopping the medication.
Fried foods and fatty foods, such as fast food, and foods high in sugar tend to be the toughest for your body to digest and the most likely to cause nausea while taking a GLP-1 medication.
Remedies for Ozempic fatigue include lowering your sleep debt, getting in sync with your circadian rhythm, and improving your sleep hygiene to help you get the best sleep possible. Eating a healthy diet, managing any GI side effects, and keeping stress and anxiety low can also help improve sleep and fatigue.
So, on average, with the recommended starting Ozempic dose of 0.25 mg, a 500 to 1000 calorie reduced diet, and exercise 3 times a week, you can expect to lose 3-5 pounds in the first month of treatment, which works out to about 3% of body weight for most overweight or obese individuals.
Ozempic works by stimulating the pancreas to release insulin, and also stops your liver from producing glucagon. This increases your insulin sensitivity while reducing your insulin resistance. It also slows down digestion and gastric emptying, helping you to feel fuller for longer.
For most people, stopping Ozempic cold turkey is not recommended. When to stop Ozempic is an individual decision you should come to with the help of your healthcare provider. If your health provider agrees it's time to stop taking Ozempic, they will provide you with instructions for tapering off your dose.
According to the FDA, they've received reports that patients taking the compounded version of Ozempic have had “adverse effects.” They also noted people could be using doses of semaglutide that are derived from a salt — which haven't been tested — rather than its pure form.