Zinc similarly inhibits Tyrosinase activity, again in effect reducing the production of melanin.
Zinc has a role in the synthesis and release of α-melanocyte stimulating hormone in bovine. [41,45] Hence, zinc may be effective in melanogenesis in human via release of this hormone. ZAG regulates melanin production by normal and malignant melanocytes.
When we look at our skin, we may notice dark spots. This can make us feel old. Although zinc oxide is not a bleaching agent that whitens skin, it is a helpful substance that treats melasma. According to the American Academy of Dermatology, applying it each day can prevent further darkening.
Research studies have demonstrated the positive effect of zinc on reducing hyperpigmentation by inhibiting melanocyte stimulating factors. Melanocytes are cells responsible for production of dark pigment, melanin. Higher levels of melanin leads to darkening of skin, pigmentation and uneven skin tone.
Vitamin C is a naturally occurring substance and an essential nutrient. It has various biological and pharmaceutical functions. It inhibits melanin synthesis through downregulation of tyrosinase enzyme activity.
Vitamin C - Popularly known as ascorbic acid, vitamin c has properties that decrease melanin on the skin. Melanin synthesis is the reason for the increase in melanin levels on the skin, and ascorbic acid is responsible for inhibiting such synthesis through the downregulation of tyrosinase enzyme activity.
Zinc oxide should always be a part of your skincare regime as it whitens your skin and heals melasma and dark spots. A broad-spectrum sunscreen with zinc oxide can help to prevent the skin from getting dark.
Assists in collagen synthesis: "Because zinc acts as an enzyme cofactor, it assists in collagen synthesis and DNA repair, which can help keep skin looking younger and healthier," Herrmann says.
Dark Spots
The American Academy of Dermatology recommends using a sunscreen containing, you guessed it, zinc oxide, to fade these spots and prevent more from forming.
It may take up to three months of topical application before you see visible results. If you haven't noticed any changes by this time, talk to your doctor about whether zinc can help your acne from the inside out. They may be able to recommend certain dietary changes or oral supplements.
Vitamins can be used to lighten your skin and lighten dark spots. Three of the best vitamins for lightening dark spots are vitamin C, vitamin B12, and vitamin E. Vitamin C helps your skin produce more collagen while inhibiting the formation of melanin.
The anti-inflammatory properties of zinc have been the reasons for its use in many common inflammatory dermatoses like acne, rosacea, eczemas, and ulcers and wounds of varied etiology.
Vitamin C is an effective skin lightener that has been described as a melanogenesis inhibitor due to its inhibition of tyrosinase and reduction of melanin and melanin intermediates, such as dopaquinone.
Vitamin D is known to enhance the rate of melanin synthesis; and this may concurrently regulate the expression of furin expression.
It is possibly safe when taken in larger doses, especially when used only for a short period of time. But taking doses higher than 40 mg daily might decrease how much copper the body absorbs. Taking very high doses of zinc is likely unsafe and might cause stomach pain, vomiting, and many other problems.
Present in the top layers of the skin, Zinc assists antioxidants by preventing new free radicals from damaging the skin, and essentially prevents wrinkle formation at the molecular level. It strengthens the cell membranes and brings new youthful cells to the surface.
Zinc helps to regulate the menstrual cycle by nourishing healthy ovarian follicles and therefore promoting ovulation. Premenstrual mood symptoms. According to a 2022 randomized clinical trial, zinc supplementation can improve PMS.
Although zinc oxide won't whiten skin, it should be used as part of your treatment regimen if you have melasma or dark spots. A broad-spectrum sunscreen with zinc oxide that has an SPF of 30 or higher can help stop additional skin darkening when applied every day.
Using zinc oxide or titanium dioxide sunscreen can make your skin look darker therefore before purchasing sunscreen avoid sunscreen having these ingredients.
Zinc can be a skin-saver for individuals who suffer from acne, with its bacteria fighting, anti-inflammatory and astringent abilities, it can be added to the skincare routine in the form of toners, masks and moisturisers.
Use of strong oxidizing agents, such as permanganate, chlorate, chromic acid, peroxide, and peracetic acid, will bleach melanin, although the process is slow, taking 16 hours. The blacker the melanin, the longer the bleach takes to decolorize the pigment.
It is suggested that deficiency of vitamin B12 causes decrease in intracellular reduction potential that leads to oxidation of the reduced glutathione and decrease in GSH/GSSG ratio. The epidermal melanocytes are then stimulated to produce melanin as the tyrosinase inhibiting effect of GSH has been diminished.
It is only possible to reduce melanin in the skin temporarily. In addition, using sunscreen as well as limiting sun exposure will also help reduce melanin and improve skin tone. However, there is no permanent method to reduce melanin, because it is determined by genetic factors.
ZINC AND SKIN HEALTH
Zinc plays an important role in skin health. It is needed for protein synthesis and wound healing and is a vital antioxidant.