How does Ozempic work? The active ingredient in Ozempic is semaglutide, which works by inducing satiety. This feeling of being satisfied or “full”, suppresses appetite. This is why it works for weight loss.
So, on average, with the recommended starting Ozempic dose of 0.25 mg, a 500 to 1000 calorie reduced diet, and exercise 3 times a week, you can expect to lose 3-5 pounds in the first month of treatment, which works out to about 3% of body weight for most overweight or obese individuals.
How can I maximise my body weight loss on Ozempic? You can assist Ozempic by lowering your overall calorie intake, moving your body where possible and limiting your alcohol consumption.
About a third of people who take Ozempic for weight loss will lose 10% or more of their body weight. Most people should expect to lose at least 5% of their starting body weight when using Ozempic for weight loss.
While Ozempic is not specifically labeled as a weight loss drug, studies sponsored by Novo Nordisk, the company that makes Ozempic, suggest people who take semaglutide—the active compound in Ozempic—may lose weight. In fact, the FDA approved semaglutide for weight loss in 2021 under the brand name Wegovy.
Although steady state levels are reached in 4 to 5 weeks, clinical effectiveness with Ozempic will vary from person to person and may take longer due to unique factors such as age, weight, amount of body fluid, additional medications you take, kidney or liver function, or your other medical conditions.
Ozempic® (semaglutide): It's one of several GLP-1 medications that are best known for their ability to help patients with type 2 diabetes control blood sugar—but the drug is also effective in helping those with obesity or overweight improve their metabolic health and lose weight.
What happens when you stop taking Ozempic? Weight loss caused by GLP-1 agonist drugs is not always permanent. In clinical trials, people who stopped taking semaglutide regained the majority of their prior weight loss within a year.
Some individuals may actually gain more weight after stopping an obesity drug than they initially lost, Conde-Knape added. Studies have similarly shown weight rebound in people who stop taking Ozempic.
Will Ozempic or Wegovy reduce belly fat? The answer appears to be yes. That Novo Nordisk-funded study of almost 2,000 overweight or obese adults without diabetes also found their visceral fat — the type that accumulates in the belly — was reduced from baseline with semaglutide, along with their total fat mass.
“Ozempic face” is a term for common side effects of the type 2 diabetes medication semaglutide (Ozempic). It can cause sagging and aging of facial skin. A doctor may recommend lifestyle modifications or facial fillers to treat these effects.
Stars like Chelsea Handler, Kyle Richards and more have spoken about the diet trend. Handler, for her part, admitted during a January 2023 episode of the “Call Her Daddy” podcast that she unknowingly took the medication.
Ozempic is only intended and approved for people with type 2 diabetes. You should not take it solely for weight loss. Doing so may prevent patients who require the medication for blood sugar management from getting it.
High fat foods or sugary foods
Ozempic can cause nausea and vomiting if taken after eating foods high in fat or sugar. It is recommended that you take Ozempic before meals, rather than after, to minimise any potential side effects from eating high-fat or high-sugar foods.
The most common side effects with Ozempic include stomach problems like nausea, vomiting, diarrhea, stomach pain and constipation. These tend to be mild-to-moderate and usually clear up in a few weeks in most people.
Moderation is key, but whole grains are heart-healthy and can help with nausea if you're experiencing adverse side effects when first starting an Ozempic regimen. Make sure you're drinking plenty of water (seltzer with lime counts!). Other healthy beverages include coffee and tea, without added sugar or fatty creamers.
The active ingredient in Ozempic is semaglutide, which works by inducing satiety. This feeling of being satisfied or “full”, suppresses appetite. This is why it works for weight loss. Semaglutide also helps the pancreas produce insulin, which is how it helps manage type 2 diabetes.
Ozempic has other common side effects, including nausea, constipation, vomiting, heartburn, gas, headache, and dizziness. Not everyone experiences side effects, and they may be mild for others.
In short, there is nothing inherently dangerous about taking Ozempic if you do not have diabetes (it does not work like insulin, which can be deadly if someone without diabetes takes it), but there is no final say on whether it is safe or not.
It is important to have your blood sugar levels checked regularly. This is the only way to know if Ozempic is working properly for you. Your doctor will recommend how frequently you should do this.
Spoiler: There was no magic diet fad involved. She lost weight over the course of two years by consistently lifting weights and doing circuit training. “My body has been objectified my entire career,” she said in an interview with Oprah Winfrey in 2021.
Oprah Winfrey recently announced that she has lost 42 pounds since starting the medication semaglutide. The medication, is available in the brand name form of Ozempic(for diabetes) and Wegovy (for weight loss).