Vitiligo can be triggered by stress to the melanin pigment-producing cells of the skin, the melanocytes. The triggers, which range from sunburn to mechanical trauma and chemical exposures, ultimately cause an autoimmune response that targets melanocytes, driving progressive skin depigmentation.
What causes vitiligo? Vitiligo is an autoimmune disease. This type of disease develops when your immune system attacks part of your own body. If you have vitiligo, your immune system attacks cells in your body called melanocytes.
Vitiligo usually begins with a few small lighter patches that develop on the skin. These patches may stay the same size for years or grow larger. New patches can appear on the skin. The new patches may be close to existing patches or far from them.
Vitiligo typically begins on your hands, forearms, feet and face, but can develop on any part of your body, including your mucous membranes (the moist lining of your mouth, nose, genital and rectal areas), your eyes and inner ears.
Stress increases the levels of catecholamines, neuropeptides, and cortisol that are higher in vitiligo patients [37–39] suggesting their role in the pathogenesis of vitiligo.
There is currently no cure for vitiligo and no way to prevent the condition.
Treatment cannot cure vitiligo.
While researchers are looking for a cure, treatment cannot currently cure this disease. Treatment can help restore lost skin color, but the color (repigmentation) may fade over time. To keep their results, many patients have maintenance treatments.
Many people who have vitiligo are often otherwise healthy. Even so, it's important to find a doctor like a dermatologist who knows about vitiligo. People who have vitiligo have a higher risk of getting some other medical conditions. You can also get painful sunburns on the skin that has lost color.
Vitiligo usually manifests in the second or third decade of life and is believed to be an acquired condition, though a positive family history is present in 30 to 40 percent of cases. Congenital vitiligo and presentation at birth is a very rare entity, but cases in infancy have been reported.
There is no "cure" for vitiligo. Sometimes patches go away on their own. But when that doesn't happen, doctors can prescribe treatments that might help even out skin tone. Some of these treatments are things you can try at home; others are done by a doctor.
Vitiligo does not pose a serious threat to one's health, but it can result in physical complications, such as eye issues, hearing problems, and sunburn. People with vitiligo also tend to be more likely to have another autoimmune disease (like thyroid disorders and some types of anemia).
Based on our findings, patients with vitiligo have a high incidence of vitamin D deficiency, and this deficiency is more common among females than males.
“Patients with sleep disorders may suffer the potential risk for vitiligo. Therefore, a bidirectional relationship exists between vitiligo and sleep disorders.”
Vitiligo sometimes runs in families, but the inheritance pattern is complex because multiple causative factors are involved. About one-fifth of people with this condition have at least one close relative who is also affected.
Vitiligo can start at any age, but usually appears before age 30. Depending on the type of vitiligo you have, it may affect: Nearly all skin surfaces. With this type, called universal vitiligo, the discoloration affects nearly all skin surfaces.
The disease does not affect life expectancy. However, it can have a significant impact on quality of life, especially psychologically and be responsible for disorders such as depression and anxiety.
Moreover, people with vitiligo lack melanin, which is the body's natural protection from the sun, so sun exposure can be particularly dangerous. That's why it's vital that people with vitiligo use broad-spectrum sun protection with an SPF (sun protection factor) of 30 and above.
Protect your skin from the sun.
A bad sunburn can worsen vitiligo. If you have a lighter skin tone, there's another advantage to protecting your skin from the sun. Without a tan, the lighter spots and patches are often less noticeable.
What Are The Early Signs Of Vitiligo On Lips? In most cases, vitiligo on lips starts with small patches of discolored skin. Though these white patches can appear anywhere on your lips, it usually occurs on the lateral lower lip.
Research suggests that most people who develop vitiligo do so during childhood. As you age, Dr. Mohta says untreated vitiligo often progresses to involve the surrounding skin or create new patches of discoloration.
Vitiligo is caused by partial or complete destruction of melanocytes in the affected skin area and influences the patient's quality of life. Besides physical involvement, vitiligo patients experience a high level of stress. Depression and Anxiety are common psychiatric disorders in vitiligo patients.
The risk of developing vitiligo in the general population is about 1%, or 1 in 100 people. That is really common. In comparison, the risk for juvenile diabetes is about 0.2%, or 1/500, and multiple sclerosis is 0.1%, or 1/1000.