“If your depression symptoms get worse as soon as you start taking an antidepressant, or they get better and then very suddenly get worse, it's a sign that the depression medication isn't working properly, and you should see your healthcare professional right away,” Hullett says.
If you feel like your antidepressant has stopped working, you're not alone. It's common for a medication that once worked wonders to become ineffective, especially if you've been taking it for a long time. Symptoms return for up to 33% of people using antidepressants — it's called breakthrough depression.
You may be curious about the signs your antidepressant dose is too low or high. Some of the most common signs that your dose is too low include reduced progress in therapy, negative feedback from loved ones, and validation from your provider that your dosage should be increased.
Your Mood or Energy Improve Too Much
If you're taking antidepressant medication and you either feel unusually elated, or you become very terse with your loved ones, feel noticeably more irritable, or have an uncharacteristic bout of rage, then it's likely that your antidepressant dose is too high.
Although this is beneficial for someone who's depressed, for someone who does not have depression, taking antidepressant medication can cause serotonin to build up in the body, resulting in serotonin syndrome. When serotonin levels are too high, the person may experience symptoms like: Agitation or restlessness.
When you're benefiting from antidepressants, you should feel: A mood that is less depressed, less irritable, happier, and more content.
It may be hard to believe that antidepressants can cause depression, but it could be true. The very reason you take depression medication can sometimes make symptoms worse. Depression is a mood disorder that can cause feelings of sadness and lack of energy, among other symptoms.
The effects of antidepressants are thought to be related to neurotransmitters or chemical messengers in the brain, such as dopamine, serotonin, and norepinephrine. As we mentioned, it can take 1 to 2 weeks for these changes to take effect, with a peak around the 6 to 8-week mark.
Most antidepressants take one to two weeks to start working. But you might feel some benefits sooner than this, such as improved sleep. Speak to your doctor if you don't feel any benefit after taking an antidepressant regularly for two to four weeks, or if you feel worse.
It's usually recommended that a course of antidepressants continues for at least 6 months after you feel better, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely.
Scientists have worked out why common anti-depressants cause around a half of users to feel emotionally 'blunted'. In a study published today, they show that the drugs affect reinforcement learning, an important behavioural process that allows us to learn from our environment.
There is new reason to be cautious about using popular antidepressants in people who are not really depressed. For the first time, research has shown that a widely used antidepressant may cause subtle changes in brain structure and function when taken by those who are not depressed.
Because SSRIs cause more serotonin to remain in circulation in the brain, the individual experiences less depressive symptoms. In fact, many people report feeling completely back to normal when taking these medications.
Antidepressants can cause changes in neurotransmitter levels and brain function; however, these changes are typically reversible once the medication is stopped.
Selective serotonin reuptake inhibitors (SSRIs) are the most prescribed type of antidepressant and include: Fluoxetine.
Antidepressants take so long to work because they inactivate not just individual serotonin transporters, but also the genes in our DNA that code for the transporter. The result over time is fewer serotonin transporters in the brain and more serotonin around to experience pleasant stimuli.
A common myth is that you need to take antidepressants forever. Many people use antidepressants for a few months and then slowly wean their way off the medication. Others take antidepressants for years before they discontinue the medication.
During the first few weeks' people commonly experience some side effects or feel worse before they begin to feel better. Although the newer Selective serotonin reuptake inhibitors (SSRIs) usually have fewer or less severe side effects than tricyclic antidepressants, various side effects can occur with them all.
9. Your Depression Worsens. “If your depression symptoms get worse as soon as you start taking an antidepressant, or they get better and then very suddenly get worse, it's a sign that the depression medication isn't working properly, and you should see your healthcare professional right away,” Hullett says.
There is no cure for depression, but many different treatments are available to manage the symptoms. The symptoms of depression vary among individuals. A treatment plan that includes medical interventions, support, and lifestyle changes can enable a person to live a normal and full life with the condition.
If you decide to stop taking antidepressants, don't quit taking them on your own. And don't stop all at once. A major drop in medication levels can trigger a relapse or other harmful symptoms, such as suicidal thoughts. Work with your doctor to create a plan to gradually reduce your medication dose over time.
It's often said that depression results from a chemical imbalance, but that figure of speech doesn't capture how complex the disease is. Research suggests that depression doesn't spring from simply having too much or too little of certain brain chemicals.
Perhaps the fundamental reason why antidepressants are so widely prescribed and used is that they fit with the 'medical model' of mental illness, which has become the standard view in western culture. This model sees depression as a medical condition which can be “fixed” in the same way as a physical injury or illness.