When to Sip. Rather than having breakfast, a cup of coffee and your multivitamin all at once, set your supplement aside for later. Enjoy your brew and meal first, then take your multivitamin about 10 or 15 minutes later, suggests Dr. Mark Moyad of the University of Michigan Medical Center.
Caffeine has a mild diuretic effect, which leads to an increase in urination. As a result, water-soluble vitamins, such as B-vitamins and vitamin C can be depleted due to fluid loss. Research also demonstrated that the higher the level of caffeine, the more it interfered with vitamin D absorption.
Their findings show that higher intake of caffeine was associated with poor vitamin D absorption in what they call “a representative sample of the American population" after adjusting for various health-related variables.
No interactions were found between caffeine and Vitamin D3.
[1] People who regularly take medications that suppress stomach acid for conditions like gastroesophageal reflux disease (GERD) or peptic ulcer disease—such as proton-pump inhibitors, H2 blockers, or other antacids—may have difficulty absorbing vitamin B12 from food.
Because they're water-soluble, you can take them with or without food and at any time of the day. That said, it's often recommended to take B vitamins in the morning due to their important role in nutrient metabolism and energy production. What's more, some people may benefit from taking B vitamins on an empty stomach.
You can—but it's probably not a good idea. For some supplements, optimal absorption can depend on the time of day taken. Not only that—taking certain vitamins, minerals, or other supplements together can also reduce absorption and may result in adverse interactions, which can be harmful to your health.
Furthermore, caffeine interferes with the metabolism of certain B vitamins, including thiamine. However, because caffeine increases stomach acid secretion, it actually boosts the absorption of vitamin B12.
Some people can develop a vitamin B12 deficiency as a result of not getting enough vitamin B12 from their diet. A diet that includes meat, fish and dairy products usually provides enough vitamin B12, but people who do not regularly eat these foods can become deficient.
Phenobarbital, phenytoin, and other anticonvulsant medications -- These medications may accelerate the body's use of vitamin D. Mineral oil -- Mineral oil also interferes with absorption. In addition, Vitamin D may enhance the effects of doxorubicin , a medicine used to treat a variety of cancers.
Interactions. Possible interactions include: Aluminum. Taking vitamin D and aluminum-containing phosphate binders, which may be used to treat high serum phosphate levels in people with chronic kidney disease, might cause harmful levels of aluminum in people with kidney failure in the long term.
We recommend taking it with a source of quality fat in the morning or when you break your fast. Avoid taking vitamin D in the evening (we'll talk about why below). Since vitamin D is a fat-soluble vitamin—meaning it doesn't dissolve in water—your body can most easily absorb it when you take it with food.
In general, the two main causes of vitamin D deficiency are: Not getting enough vitamin D in your diet and/or through sunlight. Your body isn't properly absorbing or using vitamin D.
Caffeine interferes with iron absorption, as phenolic compounds in coffee bind nonheme iron. This interaction could impact red blood cell production. When consumed with iron-rich foods, caffeine can decrease iron absorption by up to 80%.
Conclusions: Coffee consumption was associated with reduced circulating B-vitamin concentrations. The observed effect profiles indicated that coffee consumption preferentially affected the upper, but not the lower, part of the B-vitamin concentration distributions.
[1] People who regularly take medications that suppress stomach acid for conditions like gastroesophageal reflux disease (GERD) or peptic ulcer disease—such as proton-pump inhibitors, H2 blockers, or other antacids—may have difficulty absorbing vitamin B12 from food.
Because they're water-soluble, you can take them with or without food and at any time of the day. That said, it's often recommended to take B vitamins in the morning due to their important role in nutrient metabolism and energy production. What's more, some people may benefit from taking B vitamins on an empty stomach.