It's usually recommended that a course of antidepressants continues for at least 6 months after you feel better, to prevent your condition recurring when you stop. Some people with recurrent illness are advised to carry on taking medicine indefinitely.
Take your time.
Clinicians generally recommend staying on the medication for six to nine months before considering going off it. If you've had three or more recurrences of depression, make that at least two years.
When depression symptoms improve after starting an antidepressant, many people need to continue taking medication long term to prevent symptoms from returning. However, in some people, a particular antidepressant may simply stop working over time.
For people with chronic or severe depression, medication may be needed on a long-term basis. In these cases, antidepressants are often taken indefinitely. That is, in part, because depression is not an illness that can be cured.
Those who had used antidepressants for >3 years reported more severe side effects, including “weight gain”, “addiction”, “feeling not like myself ”, “withdrawal symptoms”, and “suicidality”, than those who had been on antidepressants for ≤2 years.
If the symptoms develop later or gradually, they may constitute a relapse of the depression. Ultimately, these withdrawal symptoms will improve with time, but they can be unpleasant for days and possibly even weeks. In time, the brain readjusts and people should experience a return to their normal state.
Do I have to take antidepressants forever is a question that some ask as they struggle with depression. This is one of the more common myths associated with the condition. You do not need to take antidepressants forever nor do you need to get a prescription from a counselor or therapist.
You are feeling better, and you and the doctor agree that it is time to stop. You have been taking the medicine for at least 6 months after you feel better. You are having counselling to help you cope with problems and help change how you think and feel. You are not worried about the depression coming back.
Stopping antidepressants suddenly is not dangerous but you could get withdrawal symptoms or become unwell again if you make a sudden change. If you can, stop your antidepressant when you have felt better for the last six months on medication. Plan in advance to cut down your dose gradually.
Discontinuation symptoms often include physical complaints that aren't commonly found in depression, such as dizziness, flulike symptoms, and abnormal sensations. Discontinuation symptoms disappear quickly if you take a dose of the antidepressant, while drug treatment of depression itself takes weeks to work.
If you feel like your antidepressant has stopped working, you're not alone. It's common for a medication that once worked wonders to become ineffective, especially if you've been taking it for a long time. Symptoms return for up to 33% of people using antidepressants — it's called breakthrough depression.
Some may want to quit because of side effects such as loss of sexual desire or decreased arousal. In other cases, their prescribers may recommend they stop taking the medications.
Long-term antidepressant users are risking permanent damage to their bodies, according to leading medical experts. Dr Tony Kendrick, a professor of primary care at the University of Southampton, says more urgent action needs to be taken to encourage and support long-term users to come off the medication.
You get sick.
Antidepressant discontinuation syndrome, also called antidepressant withdrawal, occurs when a person abruptly stops taking antidepressant medication. Many people who experience antidepressant withdrawal feel like they have the flu or a stomach bug. They may also experience disturbing thoughts or images.
Never stop "cold turkey." In many cases, the best way to stop taking most antidepressants is to slowly cut back your dose under the guidance of your doctor. This is called tapering. Tapering helps your brain adjust to the chemical changes and can help prevent discontinuation symptoms.
Timeline of discontinuation symptoms
Some studies found that 40% of people had symptoms for 6 weeks, while 25% experienced symptoms for 12 weeks or more. Several factors may influence the duration of symptoms, including the drug's half-life.
A course of treatment usually lasts for at least 6 months after you start to feel better. Some people with recurrent depression may be advised to take them indefinitely. Read more about antidepressant dosages.
It's important that you do not stop taking antidepressants suddenly. A dose of antidepressants should be slowly reduced, normally over 4 weeks, but sometimes longer. This is to prevent any withdrawal symptoms you might get as a reaction to coming off antidepressants suddenly.
Tranquilizers, antidepressants, some blood pressure drugs, and other medications can affect memory, usually by causing sedation or confusion. That can make it difficult to pay close attention to new things. Talk to your doctor or pharmacist if you suspect that a new medication is taking the edge off your memory.
Discontinuing an antidepressant medication usually involves reducing your dose in increments, allowing two to six weeks or longer between dose reductions. Your clinician can instruct you in tapering your dose and prescribe the appropriate dosage pills.
SSRIs treat depression by increasing levels of serotonin in the brain. Serotonin is one of the chemical messengers (neurotransmitters) that carry signals between brain nerve cells (neurons). SSRIs block the reabsorption (reuptake) of serotonin into neurons.
While antidepressants are generally intended to help with brain fog, some can cause brain fog as a side effect, depending on the medication and your unique response to it. Sedatives, pain medicine, bladder control medicine and antihistamines are some of the other types of medications that can lead to brain fog.
It is not necessarily a sign of something serious*, but more of an occasional brain glitch. Scientists have found that some things make TOTs more common – such as caffeine, fatigue, and strong emotions – and that words learned later in life are more likely to be forgotten.