Induction of ethyl ether anesthesia is therefore slow. To achieve deep anesthesia with ethyl ether in medical practice takes 15-25 min (35) (the concentration of ethyl ether used for the induction of anesthesia is usually 10 to 15 vol% or 308,000 to 462,000 mg/m³).
While ether was effective as an anesthetic, it did have its shortcomings. It was highly flammable, and once it was released into the air, it could easily cause explosions. As well as this, patients often felt a chocking sensation, and because the onset could last up to 15 minutes, the patients had to be held down.
Old-time movie villains used chloroform-soaked rags to subdue their victims, which knocked them out in seconds. In reality, physicians once used chloroform and ether as surgical anesthesia, delivering them with the help of a mask held to a patient's face for several minutes.
* Breathing Diethyl Ether can cause drowsiness, excitement, dizziness, vomiting, irregular breathing, and increased saliva. High exposure can cause unconsciousness and even death.
Ether's effect is similar to alcohol's but only lasts about 15 minutes, after which the user “sobers up” with no significant after-effects (not that I would recommend consuming it). As ether is not very soluble in water it was drunk neat in small shots preceded by a glass of water.
The effects of ether intoxication are similar to those of alcohol intoxication, but more potent. Also, due to NMDA antagonism, the user may experience distorted thinking, euphoria, and visual and auditory hallucinations at higher doses.
Toxicity. Acute: harmful by inhalation in high concentrations which can cause inebriation, sedation, unconsciousness and respiratory paralysis. Diethyl ether is irritating to the eyes, respiratory system and skin but these effects are usually reversible on removal of exposure.
Chloroform “knocks you out” for as long as it is applied, this could be for 20 minutes to two hours with a 20–30 minute recovery time; during which there will be intense shivering, severe nausea and more than likely vomiting, then a severe headache lasting hours.
Chloroform has been used by criminals to knock out, daze, or even murder victims.
In 1880 Glasgow committee concluded that chloroform was more dangerous than ether.
As mentioned previously, diethyl ether was one of the first anesthetics used in hospitals. Anesthetics make people go to sleep, or go unconscious during surgery.
Ether is made by distilling a mix of ethanol and sulphuric acid. It is highly explosive, so care must be taken both when manufacturing and administering the drug. Chloroform is an organic compound and is usually created by the chlorination of ester alcohol or methane.
Usage of ether and chloroform later declined after the development of safer, more effective inhalation anesthetics, and they are no longer used in surgery today. Chloroform, in particular, came under attack in the 20th century and was shown to be carcinogenic by ingestion in laboratory mice and rats.
Dimethoxyethane (DME) is a colorless liquid that may be used a substitute for more hazardous chemicals such as chloroform.
Ether-like: Aromatic, sweet odor often accompanied by a sweet taste. Sometimes described as a "hospital odor.” Nasal irritant. Solvent-like: Sweet odor from common solvents used in paint thinners, paint removers, adhesives, and cleaning flu- ids.
Strike the Neck
A sudden blow to the carotid artery on the side of the neck can cause a knockout, or even death due to a sudden drop in blood pressure in the brain. Furthermore, a strike on the wind pipe can have your opponent gasping for air, or even render them unconscious.
KNOCKDOWN GASES are a type of toxic industrial chemical that when inhaled can cause immediate loss of consciousness and can be fatal. Knockdown gases include hydrogen cyanide, hydrogen sulfide, and phosphine. These gases have legitimate usages, but may be used for nefarious purposes.
Drugs such as Rohypnol, GHB, GBL, and ketamine are very powerful. They can affect you very quickly, and you might not know that something is wrong. The length of time that the effects last varies. It depends on how much of the drug is in your body and if the drug is mixed with other drugs or alcohol.
Although synthesizing chloroform requires the sophisticated knowledge of a chemist, there is no permit necessary to purchase it, and the substance can be readily purchased at most chemical-supply stores.
Chloroform, which is toxic to the central nervous system, can cause a person to become unconsciousness and even be fatal at high doses.
The sleep-inducing effect of ether was first recorded 300 years earlier, when famed Swiss alchemist, philosopher and physician Paracelsus noted that its vapours would induce a state of unresponsiveness in chickens.
Diethyl ether (C4H10O) is a flammable, volatile, and colorless liquid with a sweet taste and characteristic odor.
Wear chemical protective gloves (i.e. PVA), lab coat, respirator (only when the concentration of vapor in the breathing zone exceeds the PEL) and safety glasses for all work with diethyl ether. If a splash may occur, chemical splash goggles must be worn.
The boiling point of ethanol is higher than ether due to extensive intermolecular hydrogen bonding. There is no hydrogen bonds to organize the structure of the liquid, the ether is significantly less dense than the corresponding alcohol.