Hiprex is a urinary antibacterial agent with a wide antibacterial spectrum covering both gram-positive and gram-negative organisms. Urinary antibacterial activity can be shown within 30 minutes of administration.
Within ½ hour after ingestion of a single 1-gram dose of HIPREX, antibacterial activity is demonstrable in the urine.
Hiprex has an average rating of 8.0 out of 10 from a total of 29 reviews for the treatment of Bladder Infection. 76% of reviewers reported a positive experience, while 14% reported a negative experience.
The dose of Hiprex is 1 tablet 2 times a day – every 12 hours is best. If you have a catheter your doctor may increase your dose to 1 tablet 3 times a day.
Bladder irritation and frequent urination
Large doses of methenamine hippurate (Hiprex) (higher than recommended) can cause bladder irritation, frequent and painful urination, protein in your urine, and blood in your urine. Take the medication exactly as it is prescribed.
Hiprex is a urinary antibacterial agent with a wide antibacterial spectrum covering both gram-positive and gram-negative organisms. Urinary antibacterial activity can be shown within 30 minutes of administration.
Taking higher than recommended doses of Hiprex may cause bladder irritation, painful or frequent urination, and bloody or pink urine. Tell your doctor if you have these symptoms. The dose of Hiprex for adults and children over 12 years of age is 1 tablet (1.0 g) twice daily (morning and night).
Avoid most fruits (especially citrus fruits and juices), milk and other dairy products, and other foods that make the urine less acid. Also, avoid antacids unless otherwise directed by your doctor.
It may also be recommended to avoid citrus fruits and juices (e.g., orange, grapefruit, lemon), milk and dairy products, and antacids during treatment with Hiprex, as these products may decrease the effectiveness of the medicine.
Hiprex is an antibacterial medicine that can be taken on a long-term basis to treat and prevent urinary tract infections (UTIs), for example, if you frequently get UTIs or if you have a catheter. Hiprex can be bought over-the-counter from pharmacies.
The recommended dose is one tablet twice a day. If you have a catheter your doctor may increase your dose to one tablet three times a day. Not for children aged under 6. Children aged 6 – 12 years the recommended dose is half a tablet (500mg) twice a day.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking hyoscyamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness.
Hiprex is effective only against bacterial infections in the urinary tract. It will not work for other types of bacterial infections or for viral infections (such as the common cold or flu). Unnecessary use of Hiprex can lead to its decreased effectiveness and the development of antibiotic-resistant bacteria.
Adults take 1 tablet twice daily. Children over 6 years take half to 1 tablet twice daily. You can take Hiprex with or without food, but should avoid using the following medications as they may make Hiprex less effective.
Recurrent UTIs (RUTI) are mainly caused by reinfection by the same pathogen. Having frequent sexual intercourse is one of the greatest risk factors for RUTIs. In a subgroup of individuals with coexisting morbid conditions, complicated RUTIs can lead to upper tract infections or urosepsis.
Hiprex works best in an acidic environment so consider taking vitamin-C which may help to increase the bladder's acidity levels.
Notes for Professionals: Methenamine should theoretically not be administered concurrently with food or beverages that may alter urinary pH, such as milk products and most fruits.
No interactions were found between cranberry and Hiprex.
Interactions between your drugs
No interactions were found between Hiprex and Vitamin D3.
Additionally, a number of common foods and drinks — artificial sweeteners, spicy foods, alcohol, coffee, acidic fruits, citrus, or caffeinated drinks — can irritate your bladder, and may worsen UTI symptoms — so you should steer clear of them if you have signs of a bladder infection.
Your symptoms will normally pass within 3 to 5 days of starting treatment. Make sure you complete the whole course of antibiotics that you've been prescribed, even if you're feeling better.
Drugs and Foods to Avoid
This medicine works best in acidic urine. Drinking cranberry juice will help keep urine acidic. Avoid foods that lower the acid in your urine, such as nuts or milk and other dairy products.
Water is by far the best beverage choice for someone with a UTI. Drinking at least 12 8-ounce cups of water each day while you have an infection will help flush the bacteria from your system and can speed up the healing process.