Are there any side effects? Less serious side effects include pain, bruising, bleeding, swelling, itch, or rash at the injection site. Serious side effects include allergic reactions, signs of abnormal bleeding such as prolonged bleeding or bruising easily, nausea, gut pain, or numbness.
Prophylaxis of Venous Thromboembolism in Medical Patients
The recommended dose of CLEXANE is 40 mg once daily by subcutaneous injection. Treatment with CLEXANE is prescribed for a minimum of 6 days and continued until the return to full ambulation, for a maximum of 14 days.
You should not use enoxaparin if you are allergic to enoxaparin, heparin, benzyl alcohol, or pork products, or if you have: active or uncontrolled bleeding; or. if you had decreased platelets in your blood after testing positive for a certain antibody while using enoxaparin within the past 100 days.
If you take too much: You could have dangerous levels of the drug in your body. This could lead to bleeding. Symptoms of an overdose of this drug can include: abdominal pain.
When should I stop the Clexane? The effect of clexane is shorter that warfarin – it needs to stop 24 hours prior to the surgery. Your last dose of Clexane should be on the morning before your day of surgery.
Are there any side effects? Less serious side effects include pain, bruising, bleeding, swelling, itch, or rash at the injection site. Serious side effects include allergic reactions, signs of abnormal bleeding such as prolonged bleeding or bruising easily, nausea, gut pain, or numbness.
Inject your Clexane dose at the same time each day. Injection site: Change injection sites each time to stop your skin from hardening. Missed dose: If it is nearly time for your next dose, skip the missed dose and inject your next dose at the usual time. Otherwise, inject the missed dose as soon as possible.
Testing your blood helps your doctor keep you in a safe range. If there is too much blood thinner in your body, you could bleed too much. If there is not enough, you could get a blood clot. Regular blood tests are not needed for some of the newer blood thinners.
Clexane 40mg Injection (0.4ml Each) is an anticoagulant used to prevent and treat harmful blood clots. It stops the existing clots from getting any bigger and restricts the formation of any new clot.
If you stop using clexane
It is important for you to keep having clexane injections until your doctor decides to stop them. If you just stop, or keep missing doses, without having this advice, you could get a blood clot which can be very dangerous.
Rivaroxaban is an oral anticoagulant which has the potential to replace subcutaneous Clexane in post operative prophylaxis of venous thromboembolism following knee replacement.
Signs and symptoms to look out for
collapse maybe signs of pulmonary embolism. Instructions on injecting yourself with clexane: Make sure you take the clexane at the same time every day. If you are supposed to give an injection twice a day then give the first dose in the morning and second dose 12 hours later.
It is important for you to keep having clexane injections until your doctor decides to stop them. If you just stop, or keep missing doses, without having this advice, you could get a blood clot which can be very dangerous.
Anticoagulants (applies to Clexane) liver disease
Major Potential Hazard, Low plausibility. Anticoagulants should be given with extreme caution to patients at increased risk for hemorrhage, including patients who have severe liver disease with impaired hemostasis.
Clexane (enoxaparin) is a type of anticoagulant (blood thinner) that can be used in place of, or in addition to warfarin in certain circumstances. It is given as an injection under the skin, similar to insulin for diabetes.
On the positive side, patients are able to consume many foods considered safe if they are taking any anticoagulants. These are the foods that are considered safe to consume: Meat, fish, and eggs. Milk, cheese, and yogurt.
Talk with your provider about if and how much alcohol you can drink. If you do drink alcohol, it is recommended to not have more than 2 drinks (can of beer, glass of wine, shot of spirit) per day for men or 1 drink per day for women. You may have a higher risk for bleeding if you drink more alcohol than this.
It was concluded that caffeine has the capacity to inhibit the metabolism of warfarin and enhance its plasma concentration and hence anticoagulant effects. Thus, patients should be advised to limit the frequent use of caffeine-rich products i.e. tea and coffee during warfarin therapy.
Blood thinning medications do save lives, because they can treat or prevent dangerous blood clots. But, they also pose one possible and very serious side effect: Bleeding. Since blood thinners slow the clotting of blood, unwanted and sometimes dangerous bleeding can occur with the use of these medications.
The mean life expectancy after diagnosis of NVAF was 43.3 months. In a Kaplan‐Meier analysis, patients who were treated with warfarin had a mean life expectancy of 52.0 months, whereas those who were not treated with warfarin had a corresponding life expectancy of 38.2 months (Δ = 13.8 months, p < 0.001) (fig 1).
Over an average follow-up of nearly 17 months, those taking blood thinners were 2.6 times more likely to have a stroke and 2.4 times more likely to have bleeding than those who did not take the drugs.
Direct subcutaneous injection should be given into a subcutaneous tissue skinfold of the abdomen or the upper-outer aspect of the thigh. The skinfold should be held throughout the injection. After removal of the needle, do not rub the site. Rather, place firm, even pressure to the site of injection for 1-5 minutes.
Enoxaparin is usually administered morning and/or at night through an injection underneath the skin (known as a subcutaneous injection). However, for some babies and infants, an indwelling catheter device (Insuflon™) may be used, if appropriate.