Research suggests that depression doesn't spring from simply having too much or too little of certain brain chemicals. Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, and stressful life events.
People with clinical depression often have increased levels of monoamine oxidase A (MAO-A), an enzyme that breaks down key neurotransmitters, resulting in very low levels of serotonin, dopamine and norepinephrine.
There's no single cause of depression. It can occur for a variety of reasons and it has many different triggers. For some people, an upsetting or stressful life event, such as bereavement, divorce, illness, redundancy and job or money worries, can be the cause. Different causes can often combine to trigger depression.
Smoking, obesity, eating an unhealthy diet, and a lack of physical activity are all behaviors that cause depression, according to results of one UCLA study. The risk of depression due to these risk factors varies with age.
Low levels of dopamine have been linked to Parkinson's disease, restless legs syndrome and depression. Low levels of dopamine can make you feel tired, moody, unmotivated and many other symptoms.
A dopamine imbalance can cause depression symptoms, such as apathy and feelings of hopelessness, while a serotonin imbalance can affect the processing of emotions.
Effects of overly high dopamine levels include high libido, anxiety, difficulty sleeping, increased energy, mania, stress, and improved ability to focus and learn, among others.
Research suggests that depression doesn't spring from simply having too much or too little of certain brain chemicals. Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, and stressful life events.
Untreated clinical depression is a serious problem. Untreated depression increases the chance of risky behaviors such as drug or alcohol addiction. It also can ruin relationships, cause problems at work, and make it difficult to overcome serious illnesses.
Women are nearly twice as likely as men to be diagnosed with depression. Depression can occur at any age. Some mood changes and depressed feelings occur with normal hormonal changes.
It's mainly found in those with low self-esteem, who have a poor outlook, or who feel overwhelmed by stress. Depression is also more common in people with anxiety or other mental health problems. Teens who have tried to self-harm by the age of 16 have a higher risk of having depression by the time they're young adults.
Women are nearly twice as likely to suffer from major depression than men. However, men and women are equally likely to develop bipolar disorder. While major depression can develop at any age, the average age at onset is the mid-20s.
But researchers don't know exactly what causes anxiety disorders. They suspect a combination of factors plays a role: Chemical imbalance: Severe or long-lasting stress can change the chemical balance that controls your mood. Experiencing a lot of stress over a long period can lead to an anxiety disorder.
What is the cause or basis of ADHD? It is an impulse disorder with genetic components that results from imbalances of neurotransmitters.
Serotonin. Another neurotransmitter is serotonin or the "feel good" chemical. In addition to helping regulate your mood, serotonin has a number of different jobs throughout the body from your gut to blood clotting to sexual function.
A depression not only makes a person feel sad and dejected – it can also damage the brain permanently, so the person has difficulties remembering and concentrating once the disease is over. Up to 20 percent of depression patients never make a full recovery.
Major depressive disorder isn't something that eventually “passes.” While most people feel sad at times in their lives, major depression is when a person is in a depressed mood most of the day, nearly every day, for at least two weeks.
Conclusions: The findings suggest that self-reported personality traits do not change after a typical episode of major depression. Future studies are needed to determine whether such change occurs following more severe, chronic, or recurrent episodes of depression.
Depression is known to run in families, suggesting that genetic factors contribute to the risk of developing this disease. However, research into the genetics of depression is in its early stages, and very little is known for certain about the genetic basis of the disease.
Depression is a low mood that lasts for a long time, and affects your everyday life. In its mildest form, depression can mean just being in low spirits. It doesn't stop you leading your normal life but makes everything harder to do and seem less worthwhile.
As you know, one trademark of ADHD is low levels of the neurotransmitter dopamine — a chemical released by nerve cells into the brain. Due to this lack of dopamine, people with ADHD are "chemically wired" to seek more, says John Ratey, M.D., professor of psychiatry at Harvard Medical School in Boston.
Fluoxetine, but not other selective serotonin uptake inhibitors, increases norepinephrine and dopamine extracellular levels in prefrontal cortex. Psychopharmacology (Berl).