Magnesium is best for those with magnesium deficiency, insomnia due to stress or anxiety, or muscle pain and cramping. On the other hand, melatonin is considered best for those who suffer from circadian rhythm disruption, hormonal imbalances, or melatonin deficiency.
Supplementing both the mineral magnesium and melatonin together promotes a deeper, longer, more restful sleep. Magnesium glycinate nourishes at least 300 essential metabolic activities in the body, including the relaxation of nerves and muscles, doing so with a low risk of unpleasant side effects or drug interactions*.
Magnesium glycinate is considered to be the most effective type of magnesium for bettering sleep, as it may help relax both the nervous system and your muscles. This product doesn't include any other added ingredients and is suitable for those seeking a supplement for both sleep and general use.
While this doesn't prove that magnesium alone can help with sleep, taking a magnesium supplement each night before bed won't necessarily hurt you. However, it's recommended that you see your healthcare provider before you start popping magnesium supplements at bedtime.
You can also try magnesium supplements to improve sleep, Dimitriu says. The recommended supplement dose is between 270 mg to 350 mg for men and 280 mg to 300 mg for women. However, do not exceed the upper tolerable limit of 350 mg a day or you may experience abdominal cramps and diarrhea.
If melatonin does seem to help, it's safe for most people to take nightly for one to two months. “After that, stop and see how your sleep is,” he suggests.
Dr. Umeda recommends taking the supplement about 30 minutes before bedtime. And don't take more than the recommended amount.
Taking magnesium supplements can bring a range of side effects, such as drowsiness or fatigue during the day, muscle weakness, nausea, vomiting, skin flushing or diarrhea, Gurubhagavatula said.
Some people experience stomach cramping after taking too much magnesium (around 600 mg a day). This high dosage, especially supplements with large doses of magnesium oxide, can cause a laxative effect, ironically keeping you up at night, rather than providing the sleep-inducing benefits it's well-known for.
Magnesium Oxide – A less-easily absorbed form that is commonly found in medications to treat migraines, constipation and indigestion. Magnesium Sulfate – Found in Epsom salt and absorbed through the skin, this can be some of the best magnesium powder for sleep, as well as easing aches and pains.
Magnesium Glycinate
Glycine is an essential amino acid that has important neurotransmitter functions in the brain. Glycine supplementation can improve the quality of sleep, making this form of magnesium a good choice for those with insomnia.
Magnesium is a relaxation supplement helping to relax the muscles, body, and mind. “Essentially, magnesium helps set the stage for sleep by calming the body and preparing it to sleep,” says Harris. Melatonin, on the other hand, when taken directly, impacts your body's circadian rhythm and hormonal regulation of sleep.
Specifically, vitamin D deficiency (VDD) can increase risk of sleep disorders and is associated with sleep difficulties, shorter sleep duration, and nocturnal awakenings in children and adults [13,14,15].
Supplementing vitamin B6 may improve sleep quality and duration. A 2019 study also found that taking a supplement of magnesium, melatonin, and vitamin B complex for 3 months improved sleep and helped treat insomnia. Read more about B vitamins.
The claimed benefits of magnesium supplementation range from boosts in everyday wellness — better sleep, increased energy levels and improved mood — to specific health benefits, such as lower blood pressure, reduced risk of heart disease and improvement in migraines.
Magnesium supplements can cause nausea, cramps, and diarrhea. Magnesium supplements often cause softening of stool. Interactions. Magnesium supplements may interact with certain medicines, including diuretics, heart medicines, or antibiotics.
Enhanced Relaxation: Magnesium has natural muscle relaxant properties, while melatonin helps regulate the sleep-wake cycle and promote relaxation. Taking them together can enhance the overall relaxation effect, making it easier to unwind and prepare for sleep.
Bleeding disorders: Melatonin might make bleeding worse in people with bleeding disorders. Depression: Melatonin can make symptoms of depression worse. High blood pressure: Melatonin can raise blood pressure in people who are taking certain medications to control blood pressure. Avoid using it.
Taking too much melatonin can actually cause rebound insomnia —either rendering the supplement ineffective or worse, exacerbating your already sleepless nights further. You only need tiny doses of melatonin to support your natural sleep cycle.
Taking melatonin as a sleep aid
This method is meant to help you fall asleep faster in a very short amount of time. Dr. Goldman suggests starting with 1 mg, and then increasing that amount by 1 mg (not to exceed 10 mg) every week until you've reduced the amount of time it takes you to fall asleep.
Fortunately, you can correct a magnesium deficiency with a high-quality supplement. To support sleep, we suggest 300-375 mg of magnesium each day, such as Nature's Best Magnesium 375mg.