Women with PCOS may be more likely to have multiples (twins, or more). One study found that while the multiple pregnancy rate is 1.1% in the average population, it is 9.1% for women with PCOS patients.
And that number, for people with PCOS, is typically higher, too. According to one study of IVF results for PCOS patients, women with PCOS had a “statistically significantly higher oocyte yield”—an average of 22.8 eggs per cycle, compared with the control group's 16.5.
A course of 3 to 6 cycles is recommended. About 75% to 80% women with PCOS will ovulate after CC, and a conception rate of 22% per cycle has been reported.
Hyperovulation can also accompany polycystic ovary syndrome (PCOS) and, like ovarian hyperstimulation syndrome (OHSS), it can be problematic.
PCOS can cause missed or irregular menstrual periods. Irregular periods can lead to: Infertility (inability to get pregnant). In fact, PCOS is one of the most common causes of infertility in women.
This is not due to a natural egg defect inherent in PCOS women, the poor egg quality is more likely a result of overexposure to male hormones such as testosterone.
Since follicular growth is disrupted in PCOS patients, especially during Controlled Ovarian Hyper stimulation (COH), a decreased number of good oocytes/embryos in ART cycles are a widespread problem. As previous studies have shown, various factors can affect the quality of the oocytes and embryo.
Factors that increase the chance of twins include: consuming high amounts of dairy foods, being over the age of 30, and conceiving while breastfeeding. Many fertility drugs including Clomid, Gonal-F, and Follistim also increase the odds of a twin pregnancy.
Conclusion: The PCOS phenotypes influenced the sex ratio in the offspring, suggesting that environmental factors could play a role in determination of the offspring gender.
Best age to get pregnant with PCOS
The best time for women with PCOS to get pregnant is before they turn 30. It's possible to conceive up to the age of 37, but fertility declines after the age of 32 with steeper decline occurring after age 37.
Polycystic ovary syndrome and spontaneous miscarriage
PCOS women are at risk of EPL, defined clinically as first trimester miscarriage. EPL occurs in 30 to 50% of PCOS women compared with 10 to 15% of normal women.
PCOS after pregnancy
It is important to remember that some of the symptoms of PCOS, such as hormonal imbalance and associated weight gain, can return and even worsen after pregnancy – and that being pregnant and successfully giving birth does not mean that PCOS has gone away.
In many women with PCOS, mature eggs are not released. Instead, they stay in the ovaries with a small amount of fluid (cyst) around them. The affected ovary may be slightly enlarged.
PCOS belly refers to the abdominal fat causing an increased waist-to-hip ratio, PCOS Belly will look like an apple-shaped belly rather than a pear-shaped belly. One of the most common symptoms of PCOS is weight gain, particularly around the abdominal area.
Some recent studies have demonstrated an increased risk of autism spectrum disorder (ASD) in the offspring of PCOS patients (2–5). ASD is a neurodevelopmental disease with core symptoms, including social communication disorder, narrow interests, and repetitive behaviors (6).
Women with polycystic ovary syndrome (PCOS) are at higher risk for certain problems or complications during pregnancy. In addition, infants born to mothers with PCOS are at higher risk of spending time in the neonatal intensive care unit or dying before, during, or right after birth.
A registry-based study and a case-control study show that daughters of women with PCOS are five times more likely to develop the syndrome in adulthood; they have higher levels of androgens and irregular menstrual cycles as well as abdominal obesity, higher BMI and higher blood pressure.
The quick answer to this question is that, in a twin pregnancy, it is the mother's genes that determine twins. First up, giving birth to identical twins is not genetic, but conceiving fraternal twins is. The mother may have the genetic trait of releasing two eggs in one menstrual cycle.
Everyone has the same chance of having identical twins: about 1 in 250. Identical twins do not run in families. But there are some factors that make having non-identical twins more likely: non-identical twins are more common in some ethnic groups, with the highest rate among Nigerians and the lowest among Japanese.
Normally, ovarian follicles contain egg cells, which are released during ovulation. In polycystic ovary syndrome, abnormal hormone levels prevent follicles from growing and maturing to release egg cells. Instead, these immature follicles accumulate in the ovaries. Affected women can have 12 or more of these follicles.
The large majority of women with PCOS, polycystic ovarian syndrome, that have not gotten pregnant with other treatments will be able to get pregnant and have a baby with IVF (in vitro fertilization) if they are under 40 and do their IVF at a high quality clinic.
IVF is one of the most common treatments for women with PCOS who wish to have children. Women who attempt to conceive using IVF have up to a 70% chance of becoming pregnant. Once pregnant, these women also have up to a 60% chance of a successful live birth.
The highest odds of natural conception for women with PCOS remain before the age of 35, provided if ovulation happens frequently and there are no preconditions the other partner suffers from. If primary parameters remain well in check, conception can happen within a year's time.