Researchers analyzed the health records of more than 70,000 men with erectile dysfunction and found that those who were prescribed Viagra (sildenafil), Cialis (tadalafil), Levitra (vardenafil), or similar drugs called phosphodiesterase type 5 (PDE-5) inhibitors also had: 39 percent lower death rate due to heart disease.
It improves peak oxygen consumption, reduces minute ventilation/carbon dioxide output slope, and acts as a selective pulmonary vasodilator during rest and exercise in patients with heart failure and pulmonary hypertension.
The blood flow in a normal coronary artery increased after sildenafil citrate administration. This effect is expected because of an increase in cGMP.
Sildenafil treats erectile dysfunction by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Sildenafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow easily.
Its beneficial effect on patients chronic Chagas's and diabetic cardioneuromyopathies, hypertensive and hypertrophic cardiomyopathies, with or without chronic congestive heart failure.
Side effects
Research has shown that ED medications, such as the PDE5 inhibitor Viagra, could help decrease the risk of future heart-related problems. The side effects associated with PDE5 inhibitors are usually mild.
These medicines include sildenafil (Revatio, Viagra), vardenafil, avanafil (Stendra) and tadalafil (Adcirca, Cialis, others). The pill forms generally are thought to be safe for men with high blood pressure who are otherwise in good health. These medicines aren't for men with severe heart disease.
While it may not be obvious, erectile dysfunction medication does have a direct impact on your cardiovascular system. This is because drugs like Viagra cause vasodilation, meaning they work by relaxing muscles and arteries across your whole body — not just in your penis.
have a serious heart or liver problem. have recently had a stroke, heart attack or a heart problem – your doctor should carefully check whether your heart can take the additional strain of having sex. have low blood pressure (hypotension) have a rare inherited eye disease, such as retinitis pigmentosa.
Sildenafil also interacts with alcohol, grapefruit juice, and medications that affect liver proteins. This can result in a worsening of side effects like dizziness, headaches, and flushing.
Sildenafil is a safe medication when it's used as directed. Tens of millions of men of all ages and backgrounds use it and similar ED medications on a regular basis, with serious side effects very uncommon.
Regardless of your dose or individual metabolism rate, Viagra usually wears off after 4-6 hours. Note that your erection should never last more than four hours. If it does, seek medical treatment.
Sildenafil is safe to take for a long time. There do not seem to be any lasting harmful effects from taking it for many months and years.
Official answer. You can take Viagra (sildenafil) if you have high blood pressure that is controlled by blood pressure medications.
You should take sildenafil between 30 minutes and four hours before sexual activity. The medication usually stays in your system for 4–5 hours (Zucchi, 2019; DailyMed, 2020).
Sexual activity and orgasm are shown to reduce stress due to the surge of oxytocin, the so-called "cuddle hormone," that occurs with orgasm. What's more, studies show that orgasms lower blood pressure levels -- at least among women -- and high blood pressure can lead to heart attacks.
The heart will be affected. Blood pressure drops on average 6 points systolic and 4 points diastolic. In some people who take it, this can lead to the heart responding by beating a bit more forcefully and quickly.
Alone, Viagra did not promote platelet aggregation, but it did so in the presence of a small amount of other compounds typically present when a blood vessel is damaged. In fact, Viagra caused the cells to clump at concentrations well below those achieved in patients prescribed the drug for erectile dysfunction.
Sildenafil is a medication used in the management and treatment of erectile dysfunction and pulmonary arterial hypertension. It is in the phosphodiesterase-5 inhibitor (PDE5-I) class of medications.
Most men can safely take blood thinners such as warfarin (Coumadin) and enoxaparin (Lovenox) with medications for erectile dysfunction (ED), including Viagra (sildenafil), Cialis (tadalafil) or Levitra (vardenafil).
A reduction in blood pressure throughout the body may occur because sildenafil relaxes blood vessels (arteries) throughout the body. Caution must be used in patients with low blood pressure, less than 90/50 mmHg for example.
Minor differences in packaging aside, brand name Viagra and its generic counterpart sildenafil are exactly the same medication. If you have erectile dysfunction, both medications should produce noticeable improvements in your erections and sexual performance. The key difference, as we mentioned above, is price.