Nexium Lawsuit. People who filed Nexium lawsuits claim the drug caused them to develop kidney injuries and chronic kidney disease. As of May 2023, about 12,949 Nexium and Prilosec lawsuits say AstraZeneca knew the drug could cause kidney problems but failed to warn the public.
The manufacturers of Nexium and Prilosec failed to warn doctors and patients that use of its medication could cause kidney and renal failure, including acute interstitial nephritis (AIN). In the court filings, lawyers argue the following: Nexium and Prilosec are defective and unreasonably dangerous.
Ongoing Nexium Lawsuits
As of January 2023, more than 18,500 PPI lawsuits were on file, with 13,553 pending. These claims involve several manufacturers who make a class of drugs called proton pump inhibitors, or PPIs. The first bellwether trial involving Nexium was delayed in New Jersey from late 2022 to March 2023.
The first Nexium lawsuit will go to trial on October 12, 2022. January 19, 2022 Update: There are now 13,314 PPI lawsuits in the MDL class action lawsuit.
The number of pending Nexium and Prilosec kidney damage lawsuits in the Proton Pump Inhibitor MDL is up to 13,000. Lawyers expect the first PPI lawsuit in October 2022. The first case is a Nexium lawsuit, not a Prilosec case, but the bellwether effect carries over from one drug to the next.
AstraZeneca paid a $34 million Nexium settlement in 2015 to resolve kickback allegations brought against it by the U.S. Department of Justice. DOJ officials alleged AstraZeneca paid a pharmacy-benefits company to keep Nexium's “sole and exclusive” status on medications to be prescribed.
Is NEXIUM still available by prescription? Yes. All prescription NEXIUM indications and formulations remain available with a prescription. However, Nexium 24HR is available without a prescription for the treatment of frequent heartburn.
A:The Food and Drug Administration (FDA) pulled Nexium off the market after it became clear that the medication contained unsafe levels of NDMA. The World Health Organization (WHO) considers NDMA as a “probable human carcinogen,” which means that it likely causes cancer, especially after repeated exposure.
If it has been prescribed for you, you may only take it for a few weeks or months, depending on your condition. Sometimes your doctor may advise you to take it for longer, even many years. Your doctor may suggest taking esomeprazole only when you have symptoms. This means you will not have to take it every day.
Most patients have difficulty discontinuing their PPI's because the amount of acid in their digestive system surges when they stop taking the drug, and they're often left with symptoms like excruciating stomach pain and increased heartburn.
Hundreds of consumers filed Nexium lawsuits against AstraZeneca, alleging the drug caused bone deterioration, loss of bone density and bone fractures. These Nexium lawsuits claimed the pharmaceutical company was aware of the risk of fractures but did not inform Nexium users.
Slowly taper off the PPI over 2-4 weeks (the higher the dose, the longer the taper). While the taper is being completed, use the following for bridge therapy to reduce the symptoms of rebound hyperacidity. Encourage regular aerobic exercise. Encourage a relaxation technique such as deep breathing.
The Food and Drug Administration (FDA) has accepted for review the resubmitted New Drug Application (NDA) for vonoprazan for the treatment of erosive gastroesophageal reflux disease (GERD). A Prescription Drug User Fee Act target date of November 17, 2023 has been set for the application.
These popular drugs were already linked to short-term kidney problems, but newer studies on Nexium, Prilosec and Prevacid show a link between PPIs and chronic, long-term kidney disease. More frequent use of PPIs can increase the risk of serious kidney injury.
Do not use Nexium 24HR for longer than 14 days unless your healthcare professional directs you to do so. You can repeat a 14-day regimen once every four months.
Drugs like Nexium interfere with a body's absorption of nutrients, including iron, calcium and Vitamin B12. According to the FDA, they can cause increased bone fractures, bacterial infections that are especially dangerous to elderly people and risk of pneumonia and weight gain.
OTC Nexium contains esomeprazole, the same active ingredient as the prescription version. But the dosages are a bit different. OTC Nexium only comes as a 20 mg capsule and tablet. Prescription Nexium is available as 20 mg and 40 mg capsules and a powder that can be made into an oral liquid by a pharmacist.
Tolerance and safety were good and comparable in both groups. Conclusion Gaviscon® was non-inferior to omeprazole in achieving a 24-h heartburn-free period in moderate episodic heartburn, and is a relevant effective alternative treatment in moderate GERD in primary care.
Esomeprazole (Generic Health) | healthdirect.
Another rare skin side effect is called subacute cutaneous lupus erythematosus. It typically only causes a rash or plaques on the skin, but some people experience joint pain and low blood counts, too. This is usually reversible after stopping Nexium.