RA patients had a 1.2 times higher risk of dementia than controls (adjusted hazard ratio [aHR] 1.19, 95% CI 1.16–1.23). In patients with RA, the aHR for Alzheimer's disease (AD) was 1.21 (95% CI 1.67-1.25) and the aHR for vascular dementia (VD) was 1.10 (95% CI 0.99-1.21).
A lot of people with rheumatoid arthritis (RA) report having trouble with memory, attention, and mental focus. They forget names and appointments, struggle to find the right words and have trouble making and carrying out plans.
A study on the effects of midlife RA revealed an increase in the risk of cognitive impairment and Alzheimer's dementia [10-11]. The main pathological hallmarks of AD are the extracellular deposition of β-amyloid plaques and intra-neuronal neurofibrillary tangles.
Frequent age-related comorbidities and physical inactivity in osteoarthritis patients increase risk for Alzheimer's disease, vascular dementia, and cognitive impairment.
It's possible to live a long life with RA, but it is estimated that the disease can potentially reduce life expectancy by 3 to 10 years.
End-stage rheumatoid arthritis (RA) is an advanced stage of disease in which there is severe joint damage and destruction in the absence of ongoing inflammation.
Bone erosion and destruction of cartilage can happen quickly within the first two years that you have rheumatoid arthritis, and the damage may continue to develop over time.
Alzheimer's disease. This is the most common cause of dementia. Vascular dementia. This may occur in people who have long-term high blood pressure, severe hardening of the arteries, or several small strokes.
Thyroid, kidney, liver, heart and lung problems, urinary and chest infections and strokes are among the many medical conditions that can produce dementia-like symptoms.
RA can shorten your life expectancy by an average of 10 years compared to people who don't have the disease. But people with RA are living longer than ever before. Though the disease may still affect life expectancy, it doesn't have as much impact as it did in the past.
The Social Security Administration (SSA) considers rheumatoid arthritis, or RA, a qualifying disability, but it must be advanced RA to meet the SSA's eligibility requirements. That means that you your rheumatoid arthritis has to be so severe that you will be out of work for at least 12 months.
RA is a chronic condition with no known cure. People do not die from RA. However, it can lead to serious complications that can compromise overall health. A person with RA may have a reduced life expectancy.
People with rheumatoid arthritis (RA) may appear to age faster than those who don't have the disease, but in reality, this may just be a reflection of the fact people with RA have shorter life expectancies, according to one study in Arthritis & Rheumatology.
This joint pain can be so intense that it interferes with your ability to sleep well. RA sleep-related troubles can include not being able to fall asleep or sleep long enough, having fragmented sleep or frequent awakenings, or having sleep that leaves you feeling unrefreshed in the morning.
A study published in July 2018 in Arthritis Care & Research found that people who have rheumatoid arthritis (RA) are more likely to experience depression, anxiety, and bipolar disorder in their lifetimes than those who have not been diagnosed with the autoimmune disease.
The greatest known risk factor for Alzheimer's and other dementias is increasing age, but these disorders are not a normal part of aging. While age increases risk, it is not a direct cause of Alzheimer's. Most individuals with the disease are 65 and older.
Introduction: The five-word test (5WT) is a serial verbal memory test with semantic cuing. It is proposed to rapidly evaluate memory of aging people and has previously shown its sensitivity and its specificity in identifying patients with AD.
More Evidence That Alzheimer's Disease May Be Inherited from Your Mother. Results from a new study contribute to growing evidence that if one of your parents has Alzheimer's disease, the chances of inheriting it from your mother are higher than from your father.
Some of the more common triggers for dementia like a change in environment, having personal space invaded, or being emotionally overwhelmed may be easier to handle if you mentally practice your response before you react.
other long-term health problems – dementia tends to progress more quickly if the person is living with other conditions, such as heart disease, diabetes or high blood pressure, particularly if these are not well-managed.
Stage 4. At stage 4, there's no longer inflammation in the joint. This is end-stage RA, when joints no longer work as they should. In end-stage RA, people may still experience pain, swelling, stiffness, and mobility loss. There may be lower muscle strength.
Rheumatoid arthritis is a chronic inflammatory disease that primarily affects the joints. However, rheumatoid arthritis occasionally affects other parts of the body — including the eyes. The most common eye-related symptom of rheumatoid arthritis is dryness.