Age: The risk of most leukemias increases with age. The median age of a patient diagnosed with acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) or chronic myeloid leukemia (CML) is 65 years and older. However, most cases of acute lymphocytic leukemia (ALL) occur in people under 20 years old.
A person of any age can be diagnosed with ALL, but most cases occur in children. In children and teens under age 20, ALL is the most common type of leukemia, accounting for 75% of all leukemia diagnosed in this age group. Children younger than 5 have the highest risk of ALL. (Learn more about childhood ALL statistics.)
Adults between the age of 65 and 74 have the highest risk of developing leukemia. Chronic leukemia, such as chronic lymphocytic leukemia (CLL), is the most common type of leukemia seen in people over the age of 50, with the median age of diagnosis being around 71.
Causes of leukaemia
The cause of acute leukaemia is unknown, but factors that put some people at higher risk are: exposure to intense radiation. exposure to certain chemicals, such as benzene. viruses like the Human T-Cell leukaemia virus.
Age – Generally speaking, individuals over the age of 65 are more at risk for leukemia. Demographics – While anyone can conceivably develop leukemia, white males are statistically most susceptible. Radiation exposure – Exposure to radiation from an atomic bomb increases the likelihood that leukemia cells will form.
Who gets leukemia? Although it is often thought of as a children's disease, most cases of leukemia occur in older adults. More than half of all leukemia cases occur in people over the age of 65.
Chronic Leukemia May Go Undetected
It may take months or even several years before the disease begins to cause symptoms that alert the patient that something is wrong.
When is a patient tested for leukemia? "A patient may be tested for leukemia if he or she has unexplained weight loss, night sweats or fatigue, or if he or she bruises or bleeds easily," Dr. Siddon says. "Sometimes routine blood work shows an unexplained elevated number of white blood cells."
Acute leukemia symptoms can often appear suddenly
With acute leukemia, symptoms tend to develop very quickly. You may suddenly spike a fever that won't go away, develop an infection for no apparent reason, or start bleeding spontaneously from your nose or gums and not be able to stop it.
New cases. In 2018, there were 4,516 new cases of leukaemia diagnosed in Australia (2,740 males and 1,776 females). In 2022, it is estimated that 5,202 new cases of leukaemia will be diagnosed in Australia (3,198 males and 2,004 females).
If caught early, leukemia can be cured by undergoing several cancer treatments.
While leukemia bruises can form anywhere on the body, they are most commonly found on the arms and legs.
In the United States, overall, 5-year survival among people diagnosed with leukemia is 65%. However, these statistics vary greatly according to the specific subtype of disease: Chronic lymphocytic leukemia (CLL) 5-year survival rate is 85.4%. Acute lymphocytic leukemia (ALL) 5-year survival rate is 68.8%.
Leukemia starts in the soft, inner part of the bones (bone marrow), but often moves quickly into the blood. It can then spread to other parts of the body, such as the lymph nodes, spleen, liver, central nervous system and other organs.
Swelling of lymph nodes or glands in the neck, under the arms, or in the groin. This is a common symptom that people with CLL usually notice first. The enlarged lymph nodes are not usually painful. Discomfort or fullness in the upper left part of the abdomen, caused when the spleen increases in size.
Stage 1 – A patient has high levels of white blood cells and enlarged lymph nodes. Stage 2 – A patient has high levels of white blood cells and is anemic. He or she may also have enlarged lymph nodes. Stage 3 – A patient has high levels of white blood cells and is anemic.
Leukemia symptoms commonly include fatigue, breathlessness, infections, and bruising or bleeding more easily. Leukemia* symptoms vary depending on the type of leukemia. Not everyone gets the same symptoms, and you won't necessarily have all of the symptoms. Most people with these symptoms won't have leukemia.
Blood tests are essential to accurate diagnosis of this complex disease. These tests can show whether you have leukemia cells or abnormal levels of normal cells: Blood smear: With this test, we take a drop of blood and look at it under a microscope.
During the progression of leukemia, white blood cells (neoplastic leukocytes) found in bone marrow may begin to filter into the layers of the skin, resulting in skin lesions. “It looks like red-brown to purple firm bumps or nodules and represents the leukemia cells depositing in the skin,” Forrestel says.
Acute leukemia may cause signs and symptoms that are similar to the flu. They come on suddenly within days or weeks. Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually.
Call Your Doctor About Leukemia If:
You experience unexplained bleeding, high fever, or a seizure. You may need emergency treatment for acute leukemia. You are in remission from leukemia and notice signs of recurrence, such as infection or easy bleeding. You should have a follow-up exam.