Although lupus affects people of all ages, it's most often diagnosed between the ages of 15 and 45. Race. Lupus is more common in African Americans, Hispanics and Asian Americans.
You may get rashes on any part of your body that is exposed to the sun, such as your face, arms, and hands. One common sign of lupus is a red, butterfly-shaped rash across the nose and cheeks. Chest pain. Lupus can trigger inflammation in the lining of the lungs.
Lupus symptoms can also be unclear, can come and go, and can change. On average, it takes nearly six years for people with lupus to be diagnosed, from the time they first notice their lupus symptoms.
Rashes that develop on the face and upper arms after exposure to sunlight, unexplained fevers, and painful, swollen, or stiff joints are all common lupus symptoms — and are symptoms you should tell your doctor about, says Neil Kramer, MD, a rheumatologist at the Institute for Rheumatic and Autoimmune Diseases at ...
Gender: Even though anyone can get lupus, it most often affects women. They're nine to ten times more likely than men to develop it. Age: Lupus can occur at any age, but most are diagnosed in their 20s and 30s. Race: Lupus is two to three times more common in African-American women than in Caucasian women.
No two cases of lupus are exactly alike. Signs and symptoms may come on suddenly or develop slowly, may be mild or severe, and may be temporary or permanent.
Who is at risk for SLE? SLE can affect people of all ages, including children. However, women of childbearing ages—15 to 44 years—are at greatest risk of developing SLE. Women of all ages are affected far more than men (estimates range from 4 to 12 women for every 1 man).
Antibody blood tests
The test you will hear about most is called the antinuclear antibodies test (the ANA test). 97% of people with lupus will test positive for ANA. ANA connect or bind to the nucleus or command center of the cell. This process damages and can destroy the cells.
In some people, lupus will flare, become inactive (quiescent), and go into remission—this course of the disease may or may not occur regularly throughout their life. In other people, lupus will remain in a chronic (long-lasting) state of activity. Some people will have fairly frequent flares of illness.
Common symptoms include fatigue, hair loss, sun sensitivity, painful and swollen joints, unexplained fever, skin rashes, and kidney problems. There is no one test for SLE. Usually, your doctor will ask you about your family and personal medical history and your symptoms. Your doctor will also do some laboratory tests.
If left untreated, it can put you at risk of developing life-threatening problems such as a heart attack or stroke.
Blood and urine tests.
The antinuclear antibody (ANA) test can show if your immune system is more likely to make the autoantibodies of lupus. Most people with lupus test positive for ANA. But, a positive ANA does not always mean you have lupus.
An infection, a cold or a viral illness. An injury, particularly traumatic injury. Emotional stress, such as a divorce, illness, death in the family, or other life complications. Anything that causes stress to the body, such as surgery, physical harm, pregnancy, or giving birth.
Patients who have fewer symptoms than required to meet classification criteria are said to have “pre-lupus,” “incomplete lupus,” “evolving lupus,” forme fruste lupus (a French term that translates as “incomplete or unfinished form”), or undifferentiated connective tissue disease (UCTD).
Lupus is a lifelong disease that can affect many parts of your life. But, many women with lupus live long, healthy lives. You can take steps to control your symptoms, prevent lupus flares, and cope with the challenges of lupus.
In women, the values were 8.82 (2.4 to 25.99) per 100 000 person-years and 0.34 million people annually, while in men, the estimates were 1.53 (0.41 to 4.46) per 100 000 person-years and 0.06 million people annually, respectively. Poland, the USA and Barbados had the highest estimates of SLE incidence.
Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus.
For example, untreated lupus can lead to blood disorders such as anemia or thrombosis. Other potential serious complications include: Chronic digestive distress that could include difficulty swallowing, dry mouth, indigestion, intestinal inflammation, liver enlargement, or pain when vomiting or feeling nauseous.
With close follow-up and treatment, 80-90% of people with lupus can expect to live a normal life span. It is true that medical science has not yet developed a method for curing lupus, and some people do die from the disease. However, for the majority of people living with the disease today, it will not be fatal.
Lupus can develop in people with no family history of it, but there are likely to be other autoimmune diseases in some family members.
Antinuclear antibody (ANA) autoantibodies, or antibodies produced by the immune system that attack the body's own cells, are a hallmark of lupus. ANA is usually measured as 0 to 4+ or as a titer (the number of times a blood sample can be diluted and still be positive).