All these findings suggest that the radiation sensitivity, measured in terms of carcinogenic events, increases with age among adults after age of 40–45.
Immature (undifferentiated) hematopoietic cells that have divided (proliferated) from stem cells are highly sensitive to radiation and die due to a small amount of radiation more easily than differentiated cells.
It is widely believed that human radiosensitivity increases with age due to an increase of oxidative stress, telomere attrition, a decline in DNA damage response efficiency and inflammatory response [1, 2].
Radiation exposure is a concern in both adults and children in terms of increased risk of cancer. However, children have a greater sensitivity to ionising radiation than adults, as demonstrated in epidemiological studies of exposed populations.
The nerve and muscle cells are the slowest to regenerate and are the least sensitive cells.
Some people are more sensitive to harmful effects of radiation than others. There are a number of factors that influence an individual's sensitivity to radiation. These factors include age, gender, other exposures and genetic factors. Age - In general, exposed children are more at risk than adults.
Older adults usually do well with radiation therapy. The side effects depend on the type and dose of radiation therapy and where the cancer is. For example, radiation therapy for prostate cancer can cause different side effects than radiation therapy for head and neck cancer.
The cause of radiation sensitivity may be the insufficient repair and/or misrepair of the radiation-damaged genetic material of the cells ( DNA ), for instance due to defective repair mechanisms. The individual genetic makeup of each single person determines his or her radiation sensitivity or radiation resistance.
Although radiation therapy effectively treats many types of cancer, it may also increase your likelihood of developing a different cancer in the future. For many people, the benefits of radiation therapy are worth the risk.
With aging, sensations may be reduced or changed. These changes can occur because of decreased blood flow to the nerve endings or to the spinal cord or brain.
Even at older ages, sun protection can help prevent sunburn and lower skin cancer risk. Less than half of older adults protect their skin from the sun when outside for an hour or more on a warm, sunny day. This may raise their risk of getting skin cancer.
Lung. Many studies have shown that the lung ranks among the organs that are most resistant to LDR damage.
“These Langerhans cells were resistant to radiation.” The researchers also discovered that Langerhans cells are able to resist lethal doses of radiation because they express very high levels of an important protein involved in the stress response that orchestrates DNA repair after radiotherapy.
Because the radiosensitivity of a tumor reffects the sensitivity of the tissue from which it has arisen, malignant lymphomas, which originate in lymphatic tissue, and semi- nomas, which originate in the testis, have high sensitivity to radiation.
Radiation resistance is a serious issue in radiotherapy. Increasing evidence indicates that the human gut microbiome plays a role in the development of radiation resistance. Vitamin D is an important supplement for cancer patients treated with radiotherapy.
Breast cancer: Women with breast cancer have an overall 30% chance of recurrence. Many cases happen within five years of completing the initial treatment. Cervical cancer: Of those with invasive cervical cancer, an estimated 35% will have a recurrence.
Stay Inside. Staying inside will reduce your exposure to radiation. Close and lock windows and doors. Take a shower or wipe exposed parts of your body with a damp cloth.
Symptoms may include redness, tenderness, swelling, wet sores, and peeling skin. Typically, these effects start within days or weeks of starting radiation therapy. But they can also appear months or years later.
Many find radiation scary, especially when it is associated with a nuclear power station, despite the fact that there is no difference between natural radiation and 'man-made' radiation. After an incident involving radiation, many become anxious because they cannot see, touch or smell it.
Adults over age 65 with cancer can have a stronger reaction to chemotherapy treatments. This means that they may have worse side effects or take longer to recover after chemotherapy treatment ends. It is important to remember that chemotherapy can be a treatment option for patients of any age.
The organs at risk (OAR) of radiotherapy-associated toxicity, including optic nerves, optic chiasm, retinae, lenses, brainstem, pituitary, cochlea and hippocampus, should be (properly) delineated.
More than half of the average annual radiation exposure of people in the United States comes from natural sources. The natural radionuclide, radon, is the largest natural source of exposure. Radon is a natural radioactive gas that gets into homes and buildings.
Man-made sources of radiation from medical, commercial and industrial activities contribute roughly 310 mrem more to our annual exposure. Among the largest of these sources is a computed tomography scan, which accounts for about 150 mrem. Other medical procedures make up another 150 mrem or so each year.