Steroids do not tend to cause significant side effects if they're taken for a short time or at a low dose. But sometimes they can cause unpleasant side effects, such as an increased appetite, mood changes and difficulty sleeping (insomnia). This is most common with steroid tablets.
Steroids can sometimes affect diabetes, high blood pressure or epilepsy, so you'll have your blood pressure and blood sugar levels checked from time to time. The person treating you might change the dose of your medications if needed.
Anabolic steroids can lead to early heart attacks, strokes, liver tumors, kidney failure, and serious psychiatric problems.
Steroid use can cause anxiety, depression, paranoia and psychosis in those people who have a vulnerability to mental health problems. Drug use can lead to social and emotional problems and affect a person's relationship with family and friends.
Taking steroid tablets for less than 3 weeks is unlikely to cause any significant long-term side effects. But you may get some side effects if you need to take them for longer, at a high dose or if you need frequent courses.
You could expect a dose of prednisone to stay in your system for 16.5 to 22 hours. The elimination half life of prednisone is around 3 to 4 hours. This is the time it takes for your body to reduce the plasma levels by half. It usually takes around 5.5 half lives for a drug to be completely eliminated from your system.
If symptoms such as abdominal pain, fever or unusual digestive problems (diarrhea, constipation) occur during corticosteroid therapy, notify your physician.
Talk to your doctor right away if you have more than one of these symptoms while you are using this medicine: blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, increased thirst or urination, irritability, or unusual tiredness or weakness.
Fluid retention is one of prednisone's most famous side effects. “'Moon face' is common, which is swelling in the face that can occur after you've been on steroids for a long time,” Dr. Ford notes. “You can also get swelling in the legs and midsection.”
Some people who take steroids say the drugs make them feel powerful and energetic. However, steroids are also known to increase irritability, anxiety and aggression and cause mood swings, manic symptoms and paranoia, particularly when taken in high doses.
Anabolic steroids help build muscle tissue and increase body mass by acting like the body's natural male hormone, testosterone. However, steroids cannot improve an athlete's agility or skill. Many factors determine athletic ability, including genetics, body size, age, sex, diet and how hard the athlete trains.
Physical consequences include liver tumors and cancer, jaundice, high blood pressure and increases in cholesterol levels, kidney tumors, fluid retention, and severe acne. Men may experience shrinking of the testicles, reduced sperm count, infertility, baldness, breast development, and increased risk of prostate cancer.
Long-term corticosteroid use may be associated with more serious sequel, including osteoporosis, aseptic joint necrosis, adrenal insufficiency, gastrointestinal, hepatic, and ophthalmologic effects, hyperlipidemia, growth suppression, and possible congenital malformations.
Long-term side effects
thinner bones (osteoporosis) poorly controlled diabetes. eyesight problems. high blood pressure (hypertension)
Side-effects are more likely to occur if you take a long course of oral steroids (more than 2-3 months), or if you take short courses repeatedly. The higher the dose, the greater the risk of side-effects.
Testosterone. Available in both oral and injectable forms, testosterone is widely prescribed to treat low testosterone levels and is considered the safest oral steroid.
Short-term treatment (7–14 days) with oral prednisone is used for many acute inflammatory and allergic conditions.
Prednisone affects areas of the brain that manage the regulation of different neurotransmitters, including serotonin and dopamine — the “feel-good” hormones. Feeling happy is a great side effect some people feel with prednisone.
The most frequently identified symptoms include agitation, anxiety, distractibility, fear, hypomania, indifference, insomnia, irritability, lethargy, labile mood, pressured speech, restlessness, and tearfulness.
Neuropsychiatric adverse effects during systemic corticosteroid therapy occur frequently. Cognitive deficits, particularly declarative and verbal memory deficits, have been documented during both long- and short-term glucocorticoid therapy.