Inflammatory Bowel Disease (IBD)
It includes two main subtypes: Crohn's Disease and Ulcerative Colitis. IBD can cause abdominal pain, diarrhea, bloody stools, weight loss, and fatigue.
Atrophic autoimmune gastritis (AAG) happens when your autoimmune system attacks your stomach cells. Providers diagnose EMAG and AAG with blood tests and endoscopy. Treatments for EMAG include antibiotics and other medications.
Nausea, a sore stomach, fatigue, and pins and needles. While these may seem like vague and varied symptoms, they can all be the result of a chronic inflammatory condition of the stomach known as autoimmune gastritis.
The exact cause of autoimmune disorders is unknown. One theory is that some microorganisms (such as bacteria or viruses) or drugs may trigger changes that confuse the immune system. This may happen more often in people who have genes that make them more prone to autoimmune disorders.
Autoimmune atrophic gastritis (AAG) is a chronic disease that affects the corpus-fundus of the stomach, and is characterized by the development two types of auto-antibodies: anti-parietal cells antibodies and anti-intrinsic factor antibodies.
Until about a decade ago, autoimmune gastritis was usually diagnosed based on pernicious anemia or gastric cancer or with a neuroendocrine tumor as the trigger. However, recently, autoimmune gastritis has been more frequently detected by an endoscopic examination.
Autoimmune gastritis is a chronic inflammatory disease with destruction of parietal cells of the corpus and fundus of the stomach. The known consequence is vitamin B12 deficiency and, consequently, pernicious anemia.
Stages 0, 1, and 2 are considered low risk and stage 3 and 4, high risk. In summary, advanced stage 3 and 4 have more extensive mucosal atrophy and more widespread topographic involvement of the stomach mucosa of the antrum and corpus and warrant definitive surveillance.
Research shows that the digestive condition known as leaky gut (or intestinal permeability) is a common factor in the biological mechanism that leads to the onset of autoimmune disease. Autoimmune diseases (AID) are diseases of the immune system.
Doctors Who Diagnose Autoimmune Disease
Gastroenterologists – autoimmune gastritis, autoimmune gastrointestinal dysmotility, autoimmune hepatitis, autoimmune pancreatitis, celiac disease, Crohn's disease, primary biliary cholangitis/cirrhosis, ulcerative colitis.
Classic autoimmune gastritis (AIG) is a gastric-body predominant inflammatory process mediated by antibodies which target the parietal cell H+,K+-ATPase. Patients with body-predominant AIG present with symptoms including epigastric pain, weight loss, heartburn, and nausea.
Autoimmune metaplastic atrophic gastritis is an inherited autoimmune disease that attacks parietal cells, resulting in hypochlorhydria and decreased production of intrinsic factor. Consequences include atrophic gastritis, B12 malabsorption, and, frequently, pernicious anemia.
Symptoms of autoimmune gastritis and the resulting pernicious anemia are wide ranging and often subtle: Fatigue. Depression or mood impairment. Irritability.
Gastritis is inflammation (irritation) of the stomach lining. This may be caused by many factors including infection, alcohol, particular medications and some allergic and immune conditions. Gastritis can be either acute (with severe attacks lasting a day or two) or chronic (with long-term appetite loss or nausea).
Dietary habits like scheduling regular mealtimes, eating slowly, and avoiding leftovers can help to improve symptoms of atrophic gastritis. Supplements including probiotics, vitamin B12, and N-acetylcysteine (NAC) can help alongside an anti-inflammatory diet to improve autoimmune gastritis.
Autoimmune gastritis is a progressive, chronic inflammatory disease characterized by the destruction of gastric parietal cells and loss of intrinsic factor, leading to gastric atrophy.
Having an autoimmune disease
The reason is unknown, but it is likely due to a combination of genetics and environmental factors.
But it's theorized that persistent stress (such as worry about finances, mental or physical health, or interpersonal relationships) could lead to chronic disease such as high blood pressure or autoimmune disease. What causes stress for a person is highly individual. A common example is having to speak in public.
The Link Between Autoimmune Disease and Women
Doctors aren't sure why autoimmune disease happens in the first place or why women are affected more than men. One theory is that higher levels of hormones in women, especially during the childbearing years, could make women more susceptible to autoimmune diseases.