Some mood stabilisers (oxcarbazepine, phenytoin and lithium) may well have a place in the treatment of aggressive behaviour for some individuals. The magnitude of the effect is difficult to determine, although any reduction in aggression may be considered a success in some patients.
Midazolam (a benzodiazepine) and droperidol (antidopaminergic) have both been shown to be effective and cause a reduction in aggression quickly. However, the result may not be sustained, and repeated administration may increase side effects including oversedation and respiratory depression.
Mood stabilizers for anger can be effective because they work to lessen, delay and even prevent episodes of mania and depression that may fuel these emotions.
Adaptogens, exercise, nutrition, meditation or mindfulness, omega-3 fatty acid, and vitamin D are some examples of natural mood stabilizers.
Our case report suggests that lamotrigine might be an appropriate bimodal-action drug, targeting simultaneously impulsive aggression and depressive symptoms.
Valproic acid, also known as divalproex or valproate, is a highly effective mood stabilizer. Common brand names include Depakote and Depakene. Valproic acid is often the first choice for rapid cycling, mixed mania, or mania with hallucinations or delusions.
The most widely used mood stabilizing drug is lithium. The clinical effects of lithium were discovered in the 1940s, and it has since become a widely used medication. The clinical properties of other mood stabilizers (carbamazepine, valproic acid) were discovered in the 1970s and 1980s.
Overview. Intermittent explosive disorder involves repeated, sudden episodes of impulsive, aggressive, violent behavior or angry verbal outbursts in which you react grossly out of proportion to the situation.
Literature4,5 reports that clozapine, but also olanzapine, tend to be effective in reducing aggressive behaviors in patients.
Haloperidol was more effective than risperidone for sedation and aggression but resulted in more akathisia. Ziprasidone had similar benefit to haloperidol for sedation and aggression but had fewer side effects. Droperidol resulted in less need for an additional injection than haloperidol.
Methylphenidate (MPH), a psychostimulant increasing dopamine and noradrenaline tone, is effective in reducing aggression in both CD and ADHD individuals.
De-escalation strategies are considered first-line nonpharmacologic treatment for agitation and aggression and include verbal de-escalation and environment modification.
Prozac, Paxil, Zoloft, Celexa, and Lexapro, are just a few brands of serotonin that we prescribe for those who suffer from depression, and/or anxiety disorder. There is evidence that these drugs can also improve premenopausal symptoms, even a role in the treatment of obesity and parkinson's disease.
CAPLYTA is a prescription medication used in adults for the treatment of depressive episodes associated with bipolar I or bipolar II disorder (bipolar depression). CAPLYTA can be taken alone or with the medicines lithium or valproate for bipolar depression.
Mood stabilizers are a long-term treatment that you should not stop taking without your doctor's advice. Your doctor will likely recommend that you remain on your mood stabilizers for at least two years to reduce the risk of relapse.
Drug classes most commonly associated with aggressive ADRs are anti-epileptic drugs, antidepres- sants, immunomodulatory drugs, and benzodiazepines. Many drugs may cause aggressive behavior though multiple theorized modes of action.
Quetiapine is an antipsychotic medication that treats several kinds of mental health conditions including schizophrenia and bipolar disorder. It balances the levels of dopamine and serotonin in your brain. These hormones help regulate your mood, behaviors and thoughts. The brand name of this medication is Seroquel®.
Psychotherapy. Individual or group therapy sessions that focus on building skills can be helpful. A commonly used type of therapy, cognitive behavioral therapy, helps people with intermittent explosive disorder: Identify which situations or behaviors may trigger an aggressive response.
This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed.
Lithium is a mood stabilizer that is used to treat or control the manic episodes of bipolar disorder (manic depression). Manic symptoms include hyperactivity, rushed speech, poor judgment, reduced need for sleep, aggression, and anger. Lithium also helps to prevent or lessen the intensity of manic episodes.