What are they? Long-acting injectables (LAIs) are antipsychotic medications that work to treat schizophrenia. They may reduce psychosis, which may include positive symptoms, which appear following the onset of the condition. Positive symptoms include hallucinations, delusions, and disorganized thoughts.
Long-acting injection (LAIs) allow for the slow release of medicine into the blood. Injectable medications used for individuals living with mental illness include Abilify Maintena®, Aristada®, Haldol decanoate®, Invega Sustenna®, Invega Trinza®, fluphenazine decanoate, Risperdal Consta®, and Zyprexa Relprevv®.
PP1M (Invega Sustenna) and PP3M (Invega Trinza) are both intramuscular injections of paliperidone palmitate used for long-lasting treatment of Schizophrenia. PP3M is a 3-month injection, meaning it is administered once every 3 months, while PP1M is administered once a month (11).
Haloperidol is a medication used for treating people with psychosis that can be taken by mouth or injected. As well as being an antipsychotic (preventing psychosis), it also calms people down or helps them to sleep.
Paliperidone palmitate 3-monthly injectable (PDP3M) is a novel formulation of IM injectable paliperidone palmitate with a significantly longer half-life than the once-monthly formulation. It was approved by the FDA in 2015 for use in schizophrenia and schizoaffective disorders.
The only portfolio that offers control of schizophrenia symptoms for 1, 3, or 6 months. Together, INVEGA SUSTENNA® (paliperidone palmitate), INVEGA TRINZA® (paliperidone palmitate), and newly approved INVEGA HAFYERATM (paliperidone palmitate) are part of the Janssen portfolio of long-acting injections (LAIs).
ABILIFY MAINTENA® (aripiprazole) is a prescription medicine given by injection by a healthcare professional for: treatment of schizophrenia in adults. maintenance treatment of bipolar I disorder in adults.
Clozapine – the most effective antipsychotic medication. It is saved for those who do not respond to other treatments, as people can experience a wide range of side effects and regular blood tests are required.
Risperidone extended-release injection (Risperdal Consta, Rykindo) is used alone or in combination with lithium (Lithobid) or valproate to treat people who have bipolar I disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of severe mania, and other abnormal moods).
Depo-Provera is given as an injection every three months. Depo-Provera typically suppresses ovulation, keeping your ovaries from releasing an egg. It also thickens cervical mucus to keep sperm from reaching the egg.
At a glance: the contraceptive injection
If used correctly, the contraceptive injection is more than 99% effective. It lasts for 8 or 13 weeks (depending on which injection you have) so you do not have to think about contraception every day or every time you have sex during this period.
A depot injection is a slow-release form of medication. The injection uses a liquid that releases the medication slowly, so it lasts a lot longer. Depot injections can be used for various types of drug, including some antipsychotics.
Stellate Ganglion Block (SGB) is a procedure in which a local anesthetic is injected next to the stellate ganglion, a collection of the sympathetic nerves located in the neck that helps regulate many involuntary functions such as heart rate, blood pressure and sweating.
Psychological therapies can be helpful for most people affected by mental health issues. For some mental health conditions, medications can also be helpful. Other support options include counselling, peer support, and community support services.
Antipsychotic injections for schizophrenia target neurotransmitters, including dopamine, serotonin, and glutamate, which may alleviate psychosis symptoms. After the injection, the medication slowly releases into the bloodstream for 2–12 weeks.
Antipsychotic drugs are harmful if you do not need them. For someone with dementia, antipsychotic drugs can make everyday activities more difficult. They also have dangerous side effects such as more anxiety, restlessness, loss of hunger or thirst, excessive sleeping and even death.
In this analysis, clozapine was the most toxic of the drugs examined, although only the case fatality approach could be used to assess its relative toxicity because clozapine is prescribed mainly from hospitals.
Quetiapine abuse is relatively common, and is abused far more often than any other second-generation antipsychotic. Emergency physicians should be aware of the clinical effects that may occur after second-generation antipsychotic abuse.
Schizophrenia is a chronic brain disorder that affects less than one percent of the U.S. population. When schizophrenia is active, symptoms can include delusions, hallucinations, disorganized speech, trouble with thinking and lack of motivation.
ABILIFY MAINTENA® (aripiprazole) is a once-monthly* injectable treatment for schizophrenia in adults that may help people remain relapse-free longer. You should continue to take your antipsychotic medication for 2 weeks after your first treatment with ABILIFY MAINTENA.
The US Food and Drug Administration (FDA) has approved UZEDY, a new drug for the treatment of schizophrenia. Manufactured by Teva Pharmaceutical Industries, Ltd., UZEDY uses copolymer technology to slowly release the active ingredient, risperidone, over a period of one to two months.