Ankylosing spondylitis is a form of
Ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. In particular, people who have a gene called HLA-B27 are at a greatly increased risk of developing ankylosing spondylitis. However, only some people with the gene develop the condition.
In people who may have a genetic predisposition, triggers for ankylosing spondylitis may include: Infections, such as gastrointestinal infections, urinary tract infections (UTIs), and respiratory infections. Heavy physical activity. Work stress.
Ankylosing spondylitis (AS) is probably produced by repeated episodes of Klebsiella-reactive arthritis, usually in HLA-B27-positive individuals. This concept is based on immunological, microbiological and serological considerations.
Research suggests that probiotics such as Lactobacillus may be effective in slowing the progression of AS when used in conjunction with other therapies. Taking Lactobacillus can also help relieve symptoms of IBD, which many people with AS have. However, Dr.
Bifidobacterium longum ssp.
This strain of bacteria can help prevent inflammation and provide some protection from colon cancer, intestinal infections, inflammatory bowel diseases, and even depression.
Improper deposition of human feces can lead to contamination of the soil with Klebsiella species, and hence K. pneumoniae has been isolated from such vegetables as radish, lettuce, carrots, tomatoes, and potatoes.
Klebsiella infections with varied symptomatology
Most common symptoms include abdominal pain, discomfort, bloating, constipation, diarrhoea, flatulence, nausea, heartburn, reflux, headaches, joint and muscle pain, fatigue, weakness, steatorrhoea and histamine intolerance.
There's no cure for ankylosing spondylitis (AS), but treatment is available to help relieve the symptoms. Treatment can also help delay or prevent the process of the spine joining up (fusing) and stiffening. These treatments can also help if you have non-radiographic axial spondyloarthritis.
The pain typically worsens during periods of rest or inactivity, which may cause some people to experience more pain during the middle of the night or after prolonged sitting. Usually, moving and exercise can help improve pain. Symptoms of ankylosing spondylitis vary from person to person.
Ochronosis frequently involves the spine and can mimic ankylosing spondylitis radiographically and clinically but spares the sacroiliac joint.
In 2009, two new classification terms were introduced: axial spondyloarthritis (axial SpA) and peripheral spondyloarthritis (peripheral SpA). The new terms do not replace the traditional, specific spondyloarthritis diagnoses (e.g. ankylosing spondylitis).
There is no known specific cause. Ankylosing spondylitis is relatively rare, affecting about 1 in 1,000 people. It is believed that people with the gene called HLA-B27 are at the greatest increased risk for developing ankylosing spondylitis, not everyone with the gene develops the condition.
Particularly, isolates of Klebsiella and Enterobacter have been found to emit foul odors in vitro that resemble bad breath, with concomitant production of volatile sulfides and cadaverine [5].
Certain Lactobacillus and Bifidobacterium strains have been found to reduce the growth of Klebsiella in laboratory studies. Furthermore, certain Saccharomyces boulardii strains have also been found to be effective against Klebsiella infections.
Klebsiella pneumoniae is a bacterium that lives inside human intestines. If it gets into other areas of the body, however, it can lead to illnesses like pneumonia, bloodstream infections, meningitis, and urinary tract infections.
Klebsiella pneumoniae is a gram-negative, encapsulated, non-motile bacterium found in the environment and has been associated with pneumonia in patient populations with alcohol use disorder or diabetes mellitus. The bacterium typically colonizes human mucosal surfaces of the oropharynx and gastrointestinal (GI) tract.
Klebsiella pneumoniae is an uncommon cause of septic arthritis in adults. However, late detection can cause serious complications, including joint destruction and immobility. The purpose of this study was to report a case of successfully treated septic arthritis of the hip joint (SAHJ) caused by K. pneumoniae.
Recently, the use of various supplementations containing probiotics, butyrate, phosphatidylcholine, lactoferrin, palmitoylethanolamide (PEA), silymarin and omega-3 has been proposed to treat patients with inflammatory gut diseases.
In one study, researchers found that VSL#3 (an eight-strain probiotic including lactobacilli, bifidobacilli, and Streptococcus thermophilus) significantly increased remission and positively impacted patients with UC [4] [5] [6].
Good sources of anti-inflammatory fats include extra-virgin olive oil, avocado oil, walnut oil, hemp oil, flaxseed oil, as well as avocadoes, nuts, seeds (e.g., ground flaxseeds, chia seeds, hemp hearts), and the omega-3 fats found in wild fatty fish such as salmon, mackerel, and sardines.