At the time of diagnosis, patients can have very, very high white blood cell counts. Typically a healthy person has a white blood cell count of about 4,000-11,000. Patients with acute or even chronic leukemia may come in with a white blood cell count up into the 100,000-400,000 range.
Doctors consider any platelet count above 450,000 platelets per mcL to be high and define this as thrombocytosis. In contrast, they consider any platelet count below 150,000 platelets per mcL low, referring to this as thrombocytopenia. Having a low platelet count could mean a person has leukemia.
Common leukemia signs and symptoms include: Fever or chills. Persistent fatigue, weakness. Frequent or severe infections.
Blood tests are essential to accurate diagnosis of this complex disease. These tests can show whether you have leukemia cells or abnormal levels of normal cells: Blood smear: With this test, we take a drop of blood and look at it under a microscope.
Leukocytosis refers to a high white blood cell count, which can occur for a number of reasons. Rarely, a high white blood cell count can be a symptom of certain blood cancers, such as acute myeloid leukemia, chronic myelogenous leukemia and chronic lymphocytic leukemia.
In general, for adults a count of more than 11,000 white blood cells in a microliter of blood is considered high.
Complete blood count (CBC).
This test measures the number of blood cells in a sample, including red blood cells, white blood cells, and platelets. A low level of red blood cells, white blood cells or platelets may indicate that the lymphoma is present in the bone marrow and/or blood.
If a person appears pale, has enlarged lymph nodes, swollen gums, an enlarged liver or spleen, significant bruising, bleeding, fever, persistent infections, fatigue, or a small pinpoint rash, the doctor should suspect leukemia. A blood test showing an abnormal white cell count may suggest the diagnosis.
Stage 1 – A patient has high levels of white blood cells and enlarged lymph nodes. Stage 2 – A patient has high levels of white blood cells and is anemic. He or she may also have enlarged lymph nodes. Stage 3 – A patient has high levels of white blood cells and is anemic.
The symptoms tend to be mild at first and worsen slowly. The main symptoms include: tiredness and/or anaemia (pale complexion, weakness and breathlessness) repeated infections (mouth sores, sore throat, fevers, sweats, coughing, frequent passing of urine with irritation, infected cuts and scratches, and boils)
Certain cancers such as leukemia or lymphoma can lower your platelet count. The abnormal cells in these cancers can crowd out healthy cells in the bone marrow, where platelets are made. Less common causes of a low platelet count include: Cancer that spreads to the bone.
A normal or expected WBC range in a patient with leukemia is difficult to determine. “There is no true 'normal' range for leukemia,” said Tara Graff, DO, MS, a medical oncologist with Mission Cancer and Blood in Des Moines, Iowa. “The WBC can be low in leukemia and very, very high.
Some signs of leukemia, like night sweats, fever, fatigue and achiness, resemble flu-like symptoms. Unlike symptoms of the flu, which generally subside as patients get better, leukemia symptoms generally last longer than two weeks, and may include sudden weight loss, bone and joint pain and easy bleeding or bruising.
Leukemia can produce a variety of symptoms, although most are not often apparent in the earliest stages of the malignancy. The most common symptoms of leukemia—fatigue, pale skin, weight loss and night sweats—are often attributed to other less serious conditions, such as the flu.
Chronic Leukemia May Go Undetected
It may take months or even several years before the disease begins to cause symptoms that alert the patient that something is wrong.
Chronic leukemia often causes only a few symptoms or none at all. Signs and symptoms usually develop gradually. People with a chronic leukemia often complain that they just do not feel well. The disease is often found during a routine blood test.
Our doctors may also test the blood for high levels of lactate dehydrogenase, also known as LDH. People with non-Hodgkin lymphoma sometimes produce this enzyme in increased amounts, though an elevated level of LDH may also signal other medical problems.
Itching caused by lymphoma can affect: areas of skin near lymph nodes that are affected by lymphoma. patches of skin lymphoma. your lower legs.
What Cancers Cause High WBC Counts? A number of cancers can cause elevations in WBCs. They include blood cancers such as lymphoma, acute and chronic lymphocytic leukemia, and acute and chronic myeloid leukemia.
The specific number for high (above normal) white blood cell count varies from one lab testing facility to another, but a general rule of thumb is that a count of more than 10,500 leukocytes in a microliter of blood in adults is generally considered to be high, while 4,500-10,500 is considered within the normal range.