Ezetimibe is a tablet that lowers cholesterol. It may be prescribed if statins cannot be taken, or alongside a statin for extra cholesterol-lowering. It's a 'cholesterol absorption inhibitor' that limits the absorption of cholesterol in the small intestine.
Bempedoic acid (Nexletol), a cholesterol-lowering drug intended for people who can't or won't take statins, was shown to reduce the risk of heart attack by 23 percent, according to a late-breaking clinical trial recently presented at the American College of Cardiology Conference and published online March 4 in the New ...
A low-dose statin like atorvastatin (Lipitor®) is safe for most patients, including those with mild liver enzyme abnormalities.
If you've made lifestyle changes through diet and exercise that have lowered your cholesterol levels, you may not need to continue taking a statin. These changes can help reduce your risk of heart attack, stroke, or blocked arteries while allowing you to take one less medication.
Statin alternatives include some prescription medications like ezetimibe and fibric acids. Natural remedies that some people use to help treat high cholesterol include omega-3 fatty acids and red yeast rice extract. Before stopping a statin medication and trying an alternative, speak to a doctor or pharmacist.
A newer drug called Nexletol was approved in 2020 by the FDA to treat high cholesterol, but the new study published in NEJM shows that the drug also reduces the risk of heart disease. Researchers believe this data supports using Nexletol as a safe and effective alternative for many people who cannot take statins.
A person is considered at high risk for developing heart disease if their total cholesterol level is higher than 240 mg/dL, LDL levels are higher than 160 mg/dL (190 mg/dL is even higher risk), and if the HDL level is below 40 mg/dL.
Anyone who wants to stop taking a statin should talk to a doctor. In some cases, coming off these drugs can be dangerous. The doctor may suggest reducing the dosage, combining the statin with another cholesterol lowering drug, or switching to another drug entirely.
Fear of side effects and perceived side effects are the most common reasons for declining or discontinuing statin therapy. Willingness to take a statin is high, among both patients who have declined statin therapy and those who have never been offered one.
MONDAY, March 6, 2023 (HealthDay News) -- Not everyone can tolerate statins to reduce their high cholesterol, but now a new study finds the medication bempedoic acid (Nexletol) reduced the combined rate of bad cardiovascular events by 13%.
By Lauran Neergaard • Published March 6, 2023
shows the cholesterol-lowering drug Nexletol made by Esperion Therapeutics Inc. Drugs known as statins are the first-choice treatment for high cholesterol but millions of people who can't or won't take those pills because of side effects may have another option.
People can naturally lower their cholesterol levels by adopting dietary and lifestyle changes. This can include changing the types of fats they eat, consuming soluble fiber, exercising regularly, quitting smoking, maintaining healthy body weight, limiting alcohol intake, and getting enough good-quality sleep.
As a general guide, total cholesterol levels should be: 5mmol/L or less for healthy adults. 4mmol/L or less for those at high risk.
Total cholesterol levels should be lower than 5.5 mmol/L, if you have no other risk factors. If you have cardiovascular risk factors such as high blood pressure, pre-existing cardiovascular (heart) disease or diabetes, or you smoke, the aim for LDL cholesterol levels would be less than 2 mmol/L.
High cholesterol levels are considered: too high: between 5 and 6.4mmol/l. very high: between 6.5 and 7.8mmol/l. extremely high: above 7.8mmol/l.
The new bempedoic acid drug – currently called Nexletol – is being developed by US-based Esperion Therapeutics and will go to the Therapeutics Goods Administration for approval for use in Australia.
Yes it can. Getting your blood pumping by doing exercise will reduce your cholesterol. Being active helps your body move the bad cholesterol to your liver where it can be removed out of your system.
Statins — Statins are one of the best-studied classes of medications and the most commonly used drugs for lowering LDL cholesterol. They are the most effective drugs for prevention of coronary heart disease, heart attack, stroke, and death.
These are most commonly found in fruits, vegetables including figs, avocados, nuts, oilseeds, oils such as rice bran, olive oil and whole grains including barley, oats, , wholewheat.
For patients who can't tolerate cholesterol-lowering statins, natural remedies like bergamot, garlic and green tea may be a useful alternative, based on a recent statement published in the Journal of the American College of Cardiology.
Nothing in the current research suggests that garlic is anywhere near as effective as statin drugs in treating high cholesterol. As promising as some of the evidence may sound, self-treating a condition like high cholesterol is likely to cause more harm than good.