Taking further into account a good and slightly favorable safety profile, there is evidence that the fixed combination of cinnarizine/dimenhydrinate is a potent and even superior alternative to betahistine in the treatment of vertigo related to peripheral vestibular disorders.
Betahistine is the analogue of histamine with weaker agonistic effect on histamine H1 receptors and stronger effect on histamine H3 receptors, while Cinnarizine has more effective effect on H1 receptors.
Worldwide, the first-line therapy for Meniere's vertigo attacks is betahistine, an antihistamine that reduces swelling and improves blood flow in the inner ear.
Do not stop taking this medicine suddenly, or change the dosage, without checking with your doctor. Do not use this medicine to treat any other complaints unless your doctor or pharmacist tells you to. Do not give this medicine to anyone else, even if they have the same condition as you.
Acute vertigo is best treated with nonspecific medication such as dimenhydrinate (Dramamine®) and meclizine (Bonine®).
Sometimes doctors recommend antihistamines, such as meclizine (Antivert), diphenhydramine (Benadryl), or dimenhydrinate (Dramamine) to help with vertigo episodes.
Otolith Labs' noninvasive vestibular system masking (nVSM) technology is designed to provide acute treatment for vestibulogenic vertigo. The headband device applies localized mechanical stimulation to the vestibular system through calibrated vibrations.
Your doctor may advise you to try betahistine for 6 to 12 months to see if it helps to reduce your symptoms. If it does, it can then be continued.
Are there any long-term side effects? Betahistine is unlikely to do you any harm, even if you take it for a long time. It's generally a very safe medicine.
You may need to take betahistine for a long time, such as several months or years, to prevent the symptoms of Ménière's disease.
There's no cure for Ménière's disease, but medicine can help control vertigo, nausea and vomiting. The 2 medicines usually recommended by GPs are: prochlorperazine, which helps relieve severe nausea and vomiting. antihistamines, which help relieve mild nausea, vomiting and vertigo.
Stop smoking: Many people who suffer from Meniere's disease and who regularly smoke report weakened symptoms after quitting. Plus, smoking increases your risk of hearing loss. Practice stress management: Stress and anxiety are both linked to Meniere's disease, but both can be a cause and symptom of the disease.
Several clinical trials have demonstrated that betahistine is effective in reducing the frequency and severity of vertigo, and improving vertigo-associated symptoms, including nausea and vomiting [7,9–15].
About betahistine
It typically causes attacks of dizziness with a spinning sensation (vertigo), hearing loss and noises in the ear (tinnitus). The attacks can vary in severity, and in how often they occur.
Keep taking your tablets until your doctor tells you to stop. Even when you start feeling better, your doctor may want you to carry on taking the tablets for some time to make sure that the medicine has worked completely.
Increases in vestibular blood flow and decreases in blood pressure were observed in response to betahistine infusions.
Few studies had compared the effect of betahistine and metformin before. According to our study, although betahistine group failed to decrease the body weight significantly, it prevented further weight gain with a decreasing tendency.
If your dizziness comes with nausea, try an over-the-counter (nonprescription) antihistamine, such as meclizine or dimenhydrinate (Dramamine). These may cause drowsiness. Nondrowsy antihistamines aren't as effective.
There are many names for these medications (e.g. Serc, Stemetil) but essentially they are designed to reduce nausea and discomfort during a severe attack of vertigo. This is the sort of vertigo where our visual world is spinning for longer than 20-minutes.
There are two main types of vertigo: Peripheral vertigo: This happens when there's a problem with the inner ear. Central vertigo: This occurs when there's an issue with the brain. Causes can include infection, brain tumors, traumatic brain injury or stroke.
Vitamin D and calcium supplements reduced vertigo recurrence after successful vestibular rehabilitation, especially among patients with subnormal vitamin D levels, a trial in Neurology reported.