ADHD was the first disorder found to be the result of a deficiency of a specific neurotransmitter — in this case, norepinephrine — and the first disorder found to respond to medications to correct this underlying deficiency. Like all neurotransmitters, norepinephrine is synthesized within the brain.
ADHD brains have low levels of a neurotransmitter called norepinephrine. Norepinephrine is linked arm-in-arm with dopamine. Dopamine is the thing that helps control the brain's reward and pleasure center.
As you know, one trademark of ADHD is low levels of the neurotransmitter dopamine — a chemical released by nerve cells into the brain. Due to this lack of dopamine, people with ADHD are "chemically wired" to seek more, says John Ratey, M.D., professor of psychiatry at Harvard Medical School in Boston.
What are the neurotransmitters involved in ADHD? While there's no known specific cause for ADHD, varying dopamine levels, norepinephrine, and serotonin in the brain can contribute to the severity of its symptoms.
Many people with ADHD can't screen out sensory input. Sometimes this is related to only one sensory realm, such as hearing. In fact, the phenomenon is called hyperacusis (amplified hearing), even when the disruption comes from another of the five senses.
ADHD brain fog causes people to feel unfocused and mentally exhausted. Brain fog can also cause anxiety, depression, low productivity, forgetfulness, and problems communicating with others. When all these factors combine, it becomes virtually impossible for the person to function normally.
Executive functions have other roles which affect how someone thinks. In people with ADHD, these executive dysfunctions impact thinking in numerous ways. People with ADHD don't really think faster than people without it, but it can sometimes seem like they do.
The onset of attention-deficit-hyperactivity-disorder (ADHD) in childhood is characterized by developmentally inappropriate levels of hyperactivity, impulsivity and inattention. A chronic deficit of serotonin (5-HT) at the synapse may trigger symptoms of ADHD.
If your child has ADHD, they may have low levels of a brain chemical called dopamine. That's part of a mix of their genes, environment, and brain function that experts believe may cause ADHD.
Key aspects of the reward system are underactive in ADHD brains, making it difficult to derive reward from ordinary activities. These dopamine-deficient brains experience a surge of motivation after a high-stimulation behavior triggers a release of dopamine.
Brain function and structure
Other studies have suggested that people with ADHD may have an imbalance in the level of neurotransmitters in the brain, or that these chemicals may not work properly.
The largest review ever of ADHD patient brain scans was carried out at Radboud University Nijmegen Medical Centre and published in 2018. Parts of the ADHD brain mature at a slower pace (approximately one to three years) and never reach the maturity of a person who does not have ADHD.
These may include hyperfocus, resilience, creativity, conversational skills, spontaneity, and abundant energy. Many people view these benefits as “superpowers” because those with ADHD can hone them to their advantage. People with ADHD have a unique perspective that others may find interesting and valuable.
People with ADHD have at least one defective gene, the DRD2 gene that makes it difficult for neurons to respond to dopamine, the neurotransmitter that is involved in feelings of pleasure and the regulation of attention.
Low levels of dopamine can make you feel tired, moody, unmotivated and many other symptoms. Treatments are available for many of the medical conditions linked to low dopamine levels.
Sugar and other high carb foods boost dopamine levels in the brain, leading us to crave them more often when dopamine levels are low. Since children with ADHD have chronically low levels of dopamine, they are more likely than other children to crave and eat sugary or carbohydrate-heavy foods.
The ADHD brain has been described as an “interest-based nervous system”: It seeks high-stimulation situations, stronger incentives, and more immediate rewards, which trigger a quick and intense release of dopamine and with it a rush of motivation. Hyperfocus. Dopamine is the brain's most intense reward.
People who have normal dopamine levels may still crave dopamine boosts, but people with ADHD have dopamine voids to fill so that craving is more frequent. Substances, experiences, and activities that cause dopamine boosts are often addictive, even if many of them wouldn't cause an addiction in the average person.
Anecdotal evidence from adults sharing ADHD stories online suggests that many experience brain fog, low motivation, and fatigue. Tiredness is not part of the official diagnostic criteria for ADHD , but a handful of studies do suggest that some people with ADHD experience fatigue.
Abstract. Antidepressants differ in their effectiveness for treating attention-deficit/hyperactivity disorder (ADHD) in adults and children. None are as effective as psychostimulants for treating the attentional and cognitive symptoms, but they can help reduce impulsive and hyperactive behavior.
Does ADHD affect IQ? A popular misconception is that all children with attention deficit hyperactivity disorder (ADHD) are naturally smarter and have a higher IQ than children without ADHD. However, there is no correlation between this condition and intelligence.
Though brain scans cannot yet reliably diagnose ADHD, some scientists are using them to identify environmental and prenatal factors that affect symptoms, and to better understand how stimulant medications trigger symptom control vs. side effects.
While all kinds of people can fall in love, the experience of people with ADHD falling in love can be more intense for them. This is because the person with ADHD can hyperfocus on the person they are in love with.