Two GLP-1 medications are currently approved for weight loss: Liraglutide (Saxenda) and semaglutide (Wegovy). Both medications are approved for long-term use. Some other GLP-1 drugs like Ozempic are approved for diabetes, but do not have full approval for weight-loss use.
Mounjaro (tirzepatide), Ozempic (semaglutide), and Trulicity (dulaglutide) are examples of diabetes medications that can cause significant weight loss. Metformin and Jardiance (empagliflozin) may also cause weight loss but not as much.
On average, a user can lose about 3 to 5% of their body weight after using Ozempic for a month regularly. This equates to about 4 to 6 pounds on average. Using a higher potency of the drug may result in more weight loss, but it isn't recommended that you start taking it right away.
Once you begin using Ozempic, some people can find it takes several weeks to see any weight loss, yet others may see some weight loss within a week or 2. While it can be difficult, try to remain patient — change looks different for everyone.
A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
Other serious side effects of Ozempic include thyroid tumors, pancreatitis, changes in vision, hypoglycemia, gallbladder issues, kidney failure and cancer. The most severe complications Shah sees in her patients are pancreatitis and gallbladder issues — either can lead to hospitalization.
Ozempic can cause nausea and vomiting if taken after eating foods high in fat or sugar. It is recommended that you take Ozempic before meals, rather than after, to minimise any potential side effects from eating high-fat or high-sugar foods.
While metformin is a more common first-choice medication for Type 2 diabetes, weight loss is more likely with Ozempic. Ozempic can also lower your risk of heart attack and stroke if you have diabetes and heart disease. And it has been shown to have potential benefits for the kidneys.
You start feeling those usual hunger pangs again, and consequently, you may start eating more to satisfy that hunger. An increase in your consumption can lead to the regaining of weight that was lost. A 2022 study found that most individuals gain weight back a year after stopping the medication.
If you take Wegovy or Ozempic to lose weight, will you need to keep taking the drugs indefinitely? Yes. As with many chronic conditions, most people who use the drugs for diabetes or weight loss will need to keep taking them to keep benefiting from them.
Ozempic is also used off-label for weight loss. In particular, it can help reduce the amount of belly fat. This is because Ozempic works by making you feel fuller for longer, which can help you resist overeating by controlling cravings and hunger.
You should not use Ozempic if you or an immediate family member has had thyroid cancer in the past, or if you have a rare form of cancer called multiple endocrine neoplasia syndrome type 2. If you're taking Ozempic and have symptoms of a thyroid tumor, contact your doctor right away.
If you stop taking Ozempic, the weight you lost will likely return, fast. People who ceased use of semaglutide gained back, on average, a full two-thirds of the weight they had lost on the drug within one year, according to an August 2022 study, the Wall Street Journal reports.
Eating a balanced diet low in calories, fat, and sugar is essential when using Ozempic for weight loss. This is because certain types of foods can interact with the medication, reducing its effectiveness and potentially causing weight gain.
In rare cases, the use of Ozempic may cause anxiety and mood swings, irritability, shakiness, and confusion. However, when you take other medications along with Ozempic, it may escalate anxiety or mood change. Hence, discuss these potential issues with your physician beforehand to avoid any side effects.
“It boosts the release of insulin by the pancreas in response to food intake, which helps to control blood sugar. Likewise, it reduces the release of glucagon—a hormone that increases blood glucose—thereby also helping to control blood sugar.” Ozempic is a once-weekly self-administered injection of semaglutide.
There is a potential risk of kidney injury associated with both Wegovy and Ozempic use since semaglutide is cleared out of your blood through the kidneys.
The active ingredient in Ozempic is semaglutide, which works by inducing satiety. This feeling of being satisfied or “full”, suppresses appetite. This is why it works for weight loss. Semaglutide also helps the pancreas produce insulin, which is how it helps manage type 2 diabetes.
(No member of the Kardashian family has publically said they use Ozempic.) Ozempic is the brand name for the medication semaglutide, which treats diabetes by balancing out hormones like insulin.