Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Naproxen (Aleve), aspirin and ibuprofen (Motrin, Advil) are available over the counter. Others like indomethacin (Indocin) and celecoxib (Celebrex) require a prescription.
NSAIDs are the most effective oral medicines for OA. They include ibuprofen (Motrin, Advil) naproxen (Aleve) and diclofenac (Voltaren, others). All work by blocking enzymes that cause pain and swelling.
First-Line Management: NSAIDS and Corticosteroids
Medications, considered to be fast-acting, are nonsteroidal anti-inflammatory drugs (NSAIDs) including acetylsalicylate (Aspirin), naproxen (Naprosyn), ibuprofen (Advil and Motrin), and etodolac (Lodine).
1. Omega-3 fatty acids. Omega-3 fatty acids , which are abundant in fatty fish such as salmon or tuna, are among the most potent anti-inflammatory supplements. These supplements may help fight several types of inflammation, including vascular inflammation.
Methotrexate is widely regarded as one of the safest of all arthritis drugs, though it carries some potential downsides.
Besides ibuprofen and naproxen, other examples of prescription NSAIDs include diclofenac (Cambia, Cataflam, Voltaren), etodolac, meloxicam (Mobic), oxaprozin (Daypro), and piroxicam (Feldene).
Research shows diclofenac is the strongest and most effective non-steroidal anti-inflammatory medicine available.10 Diclofenec is sold under the prescription brand names Cambia, Cataflam, Zipsor, and Zorvolex. It is also available as a topical gel, Voltaren, which is available over the counter.
The newest drugs for the treatment of rheumatoid arthritis are the Janus kinase (JAK) inhibitors, which are FDA approved under the brand names Rinvoq, Olumiant, and Xeljanz.
Glucosamine and chondroitin are two of the most commonly used supplements for arthritis. They're components of cartilage—the substance that cushions the joints.
A doctor may prescribe daily ibuprofen to treat chronic pain associated with arthritis. In these cases, a doctor may prescribe or recommend slow-release ibuprofen tablets. A person can take these once or twice per day depending on the dose.
Just One Injection, Once a Month. SIMPONI® is taken with the medicine methotrexate as directed. Keep in mind that, while how often you take a medicine matters, there are other important factors to consider. Talk to your doctor about treatment options and what might be right for you.
Heat and cold.
Use of heat, such as applying heating pads to aching joints, taking hot baths or showers, or immersing painful joints in warm paraffin wax, can help relieve pain temporarily. Be careful not to burn yourself. Use heating pads for no more than 20 minutes at a time.
Meloxicam is considered a stronger medicine than ibuprofen. Meloxicam is only available on prescription and ibuprofen is available over the counter as well as on prescription. Meloxicam is a long-acting medicine that only needs to be given once a day.
1. FATTY FISH. Fish like salmon, mackerel, sardines, and tuna give you protein and the omega-3 fatty acids EPA and DHA. These components reduce inflammation in the body.
Ibuprofen (Advil, Motrin) and Naproxen (Aleve).
“In general, pain that is associated with inflammation, like swelling or acute injury, is better treated with ibuprofen or naproxen,” says Matthew Sutton, MD, a Family Medicine physician at The Iowa Clinic's West Des Moines campus.
Voltaren helps alleviate joint pain due to arthritis in the hands, wrists, elbows, feet, ankles, and knees. Apply Voltaren gel to the skin over the affected part of the body. Do not use on more than two body areas at the same time.
Celecoxib is commonly known by the brand name Celebrex®. Celecoxib (Sell-e-COX-eb) is used to relieve some symptoms caused by arthritis, such as inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will help you only as long as you continue to take it.
If osteoarthritis of the hip causes aching pain and limits your ability to move without discomfort, your doctor may recommend an over-the-counter pain relief medication. Many doctors recommend acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs), which include aspirin, ibuprofen, and naproxen.
Pfizer's Xeljanz (tofacitinib) is used to treat rheumatoid arthritis and psoriatic arthritis by relieving pain and swelling in the joints. Xeljanz can also be used to treat symptoms of ulcerative colitis by lowering inflammation.