Lithium is found in trace amounts in many different whole foods, including potatoes, tomatoes, cereals, cabbage and mineral water. However, the amount of lithium may vary depending on the area of the country or world where the food is grown.
Lithium is a highly reactive, light metal naturally found in very low levels throughout the body. It is available as a dietary supplement and is commonly found in drinking water and in many foods, including grains, vegetables, mustard, kelp, pistachios, dairy, fish, and meat.
Lithium is a naturally occurring mineral, and trace amounts are present in the water many of us drink. And areas with more lithium in the water supply tend to have lower suicide rates! So, very tiny amounts of lithium —less than 1% of the lithium even in low-dose dietary supplements—might sometimes be helpful.
Dietary changes, particularly those containing caffeine and salt, may affect lithium levels and increase your risk of developing lithium toxicity. Salt consumption can cause fluctuations in serum lithium levels. While taking lithium, do not make sudden changes to your salt intake.
Avoid excessive intake of caffeinated beverages, such as coffee, tea, cola or energy drinks, since these may decrease levels of lithium and decrease effectiveness of the medication. Discontinuing caffeine use may increase lithium levels. Consult your health care provider before reducing or stopping caffeine use.
No interactions were found between lithium and Vitamin D3.
Lithium in Food Products
The main sources of Li in the diet are cereals, potatoes, tomatoes, cabbage, and some mineral waters [44]. It may also be found in some spices such as nutmeg, coriander seeds, or cumin; however, their share in the total supply of this element is negligible in many geographic regions [49].
Lithium may cause sodium depletion, especially during initial therapy until consistent blood levels are achieved. A low-sodium (salt-restricted) diet can decrease lithium elimination, leading to increased lithium levels and risk of toxicity in lithium users who reduce their salt intake.
Where is lithium available from? With 8 million tons, Chile has the world's largest known lithium reserves. This puts the South American country ahead of Australia (2.7 million tons), Argentina (2 million tons) and China (1 million tons). Within Europe, Portugal has smaller quantities of the valuable raw material.
When 7-Up was first invented, one of its ingredients was lithium salts. In fact, the fizzy drink was originally known as “Bib-Label Lithiated Lemon-Lime Soda,” according to the Huffington Post.
Lithium is a common medicine used to help calm mood for treating people with mental disorders. Since such disorders need lifelong treatment, long-term use of lithium may be harmful to organs, such as the kidneys.
Amiloride is recommended as a diuretic because it blocks entry of lithium through the epithelial sodium channel in the collecting duct. This reduces lithium accumulation and may improve kidney function in patients on long-term treatment.
Lithium-ion (Li-ion) batteries are used in many products such as electronics, toys, wireless headphones, handheld power tools, small and large appliances, electric vehicles and electrical energy storage systems.
Irritability, Anger, and Rage: Lithium Deficiency Syndrome (Townsend Letter)
With the lithium caffeine drug interaction, caffeine ultimately reduces the blood levels of lithium. If caffeine intake increases, this could potentially lead to treatment failure and the patient having a return of bipolar symptoms.
Common Nutrient Depletions
Antipsychotics, like lithium, can inhibit the absorption of B vitamins and folic acid, leading to lower levels in the body. There are many studies being done to figure out why this happens.
Lithium is also associated with reduced levels of serum vitamin B12 and is postulated to result in long term administration induced changes at cellular and genomic expression levels [8].
Amiloride is recommended as a diuretic because it blocks entry of lithium through the epithelial sodium channel in the collecting duct. This reduces lithium accumulation and may improve kidney function in patients on long-term treatment.
Volume depletion from diuretics, dehydration, febrile illness, or gastrointestinal loss can lead to elevated lithium levels in the serum[9]. The serum elimination half-life of lithium can vary from 12 to 27 hours.
Heavy caffeine consumption can affect the blood levels of lithium, a mood stabilizer that doctors commonly use to treat bipolar disorder. The body excretes lithium in the urine. As caffeine is a diuretic, it may lower the levels of lithium in the body by increasing the urine output.
Muscular weakness develops early in lithium toxicity, and may occur at lithium levels below 2 mEq/L. Muscle hyperirritability includes fasciculations, twitching, clonic movements of whole limbs. The development of swollen/painful joints and polyarthralgia were unrelated to dosage.
Results: There were no effects of stressors on behavior. Effects of Li were demonstrated in males but not females with no interactions between stress and Li. Conclusions: The behavioral effects of Li in this study were not affected by stress.
People with bipolar disorder who are taking lithium (a common standard treatment for this disorder) or are experiencing a manic episode often have low levels of Folic Acid. Supplementing with this vitamin seems to enhance the effects of lithium. Typical dosages are between 400-600 mcg a day for an adult.