Lupus nephritis can also cause high blood pressure (hypertension). If left untreated, it can put you at risk of developing life-threatening problems such as a heart attack or stroke.
However, the majority of people with lupus can expect a normal or near-normal life expectancy. Research has shown that many people with a lupus diagnosis have been living with the disease for up to 40 years. As research progresses, scientists hope to identify people who have a risk of lupus through genetic studies.
For example, untreated lupus can lead to blood disorders such as anemia or thrombosis. Other potential serious complications include: Chronic digestive distress that could include difficulty swallowing, dry mouth, indigestion, intestinal inflammation, liver enlargement, or pain when vomiting or feeling nauseous.
Lupus-Related Damage Over Time
Physiological damage from lupus accumulates over time, and it can lead to joint destruction and chronic pain.
Lupus can cause serious kidney damage, and kidney failure is one of the leading causes of death among people with lupus. Brain and central nervous system. If your brain is affected by lupus, you may experience headaches, dizziness, behavior changes, vision problems, and even strokes or seizures.
In chronic illnesses like lupus the following may occur: Symptoms come and go for months or years before a diagnosis is certain. Laboratory tests may change over the course of treatment. You may not know for months whether a prescribed treatment works; it may not work, and it may be necessary to try another medication.
Sjogren's syndrome is a relatively common disease, although often under-diagnosed. Sjogren's syndrome can occur alone or in association with other autoimmune diseases, most commonly lupus and rheumatoid arthritis (RA).
Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus. Lungs About 50% of people with SLE will experience lung involvement during the course of their disease.
With close follow-up and treatment, 80-90% of people with lupus can expect to live a normal life span. It is true that medical science has not yet developed a method for curing lupus, and some people do die from the disease. However, for the majority of people living with the disease today, it will not be fatal.
Lupus nephritis tends to develop within 5 years of the appearance of initial lupus symptoms. The condition affects about 40% of people who have SLE and can lead to end-stage kidney disease (ESKD) in 22% of patients over a period of 15 years.
Lupus flares can be mild to serious, and they do not follow a pattern. However, with treatment, many people with lupus can manage the disease. Anyone can get lupus, but women are more likely to get the disease than men are.
Class 4, or diffuse lupus nephritis
Class 4 involves damage to more than half of the glomerulus. A person will have high blood pressure. They may require dialysis as kidney function begins to worsen.
The times when your symptoms get worse and you feel sick are called flares. Flares can come and go. You may have swelling and rashes one week and no symptoms the next. Sometimes flares happen without clear symptoms and are seen only with laboratory tests.
An infection, a cold or a viral illness. An injury, particularly traumatic injury. Emotional stress, such as a divorce, illness, death in the family, or other life complications. Anything that causes stress to the body, such as surgery, physical harm, pregnancy, or giving birth.
You should also be aware of symptoms that require that you see a doctor immediately. These include: Severe abdominal pain. Chest pain or shortness of breath.
Palliative (pronounced PAH-lee-uh-tiv) care is a health care approach that tends to the physical, emotional, social and spiritual needs of a person with an illness and the needs of his or her family. It can be offered to people at any age and at any point in an illness such as lupus.
Muscle and joint pain.
This affects most people with lupus. Common areas for muscle pain and swelling include the neck, thighs, shoulders, and upper arms.
Lupus and the intestines
Lupus can rarely cause vasculitis (inflammation of the blood vessels) in the intestines, sometimes called lupus enteritis. Symptoms include: Abdominal pain (pain in the belly area) Feeling very full or bloated.
Saturated Fat and Trans Fat
Foods that contain saturated fat or trans fat also contain steroids that can contribute to weight gain because they increase your appetite. It is best to limit both as much as possible since being overweight or obese could worsen your lupus symptoms.
Undifferentiated Connective Tissue Disease
“There are people who have a milder form of an autoimmune disease who just don't meet the classification criteria for lupus. We call that undifferentiated connective tissue disease (UCTD),” says Dr. Petri.
Both lupus and MS can follow a pattern of remission and relapse which repeats. They can both cause brain lesions that look similar on magnetic resonance imaging (MRI). While the nerves are the primary target of MS, lupus sometimes affects the nerves as well.
Weight changes — Lupus can sometimes cause weight loss or weight gain. Weight loss may be unintentional and due to decreased appetite or problems with the digestive system (see 'Digestive system' below).