They can cause movement disorders such as twitching and restlessness, sedation and weight gain, and lead to diabetes. Because of these side effects, antipsychotic drugs are usually only used to treat severe mental illnesses such as schizophrenia or bipolar disorder.
Both typical and atypical antipsychotics commonly cause side effects like drowsiness, dizziness, blurred vision, constipation, nausea, and vomiting, per the NIMH. These often go away. But the drugs can also cause serious long-term side effects.
What happens if a normal person takes olanzapine? Olanzapine is prescribed for people who have chronic schizophrenia and bipolar disorder. In ordinary people, intake of olanzapine increases weight by at least 2–3 kgs over six weeks. Other side effects include dry mouth, tremors, restlessness, and muscle contractions.
Clozapine may cause drowsiness, blurred vision, convulsions (seizures), or to have trouble with thinking or controlling body movements, which may lead to falls, fractures or other injuries.
Previous research has also shown that the use of antipsychotics may raise the risk of metabolic syndrome in patients with schizophrenia. Metabolic syndrome has, in turn, been associated with heart disease and diabetes.
If you experience psychotic symptoms, your doctor may offer you antipsychotic medication to help you with your symptoms. Antipsychotics can help manage your symptoms of psychosis. This can help you feel more in control of your life, particularly if you are finding the psychotic symptoms distressing.
Quetiapine can cause changes in the way your body functions. You may have hyperglycemia (high blood sugar), increased cholesterol and triglycerides (fats in the blood), or weight gain. High blood sugar can occur in people with or without diabetes.
Undoubtedly the most significant barrier to use of clozapine is the stringent restrictions around blood monitoring. Clozapine was first introduced in the 1970s in Europe, but was withdrawn after the drug was shown to be associated with agranulocytosis—an acute condition involving severe leukopenia.
Clozapine has unique and powerful side effects and risks, which often make it a drug of last resort.
Potentially life-threatening side effects can occur if a patient who has missed clozapine for more than 48 hours is put back on their original dose. Pharmacy in conjunction with the patient's Consultant will provide advice if a patient has not taken clozapine for more than 48 hours.
Your guide to medication Olanzapine. Olanzapine is an atypical antipsychotic used to treat bipolar disorder, schizophrenia and psychosis. What can olanzapine be used for? If you are 18 or over, the doctor can prescribe olanzapine for you as a licensed medicine for mania, schizophrenia and bipolar disorder.
Second-generation antipsychotics, such as quetiapine and olanzapine, are often abuse for their sedative and anxiolytic effects. Addicts seek out the calming and hallucinogenic effects caused by quetiapine and olanzapine.
For neurological, neuropsychological, neurophysiological, and metabolic abnormalities of cerebral function, in fact, there is evidence suggesting that antipsychotic medications decrease the abnormalities and return the brain to more normal function.
Most antipsychotic drugs are known to block some of the dopamine receptors in the brain. This reduces the flow of these messages, which can help to reduce your psychotic symptoms. Affecting other brain chemicals. Most antipsychotics are known to affect other brain chemicals too.
Agitation and sedation: Some people feel “wired” and unable to stop moving when taking antipsychotics. This effect may be mistaken for a worsening of illness rather than a side-effect of the medication. These same drugs can also have the opposite effect, making people feel tired.
Studies have suggested that psychiatric drugs may do more harm than good, especially in the long-term. Antipsychotics have numerous serious and debilitating side effects including: Movement effects: Tremors, muscle stiffness and tics can occur. The higher the dose, the more severe these effects.
Clozapine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. You should not take clozapine if you are allergic to it.
Abrupt withdrawal of clozapine has been associated with symptoms of “cholinergic rebound,” including nausea, vomiting, hypersalivation, diarrhea, diaphoresis, insomnia, and agitation, as well as rapid onset of psychosis.
Clozapine is associated with several significant adverse effects, including agranulocytosis, neutropenia, constipation (which can be severe), myocarditis and adverse metabolic effects. These adverse effects are not necessarily dose-related and may occur at any time during treatment.
Clozapine differs from conventional antipsychotics for its greater efficacy in controlling positive symptoms in people with treatment-resistant illness and by inducing few extra-pyramidal effects (Kane 1988, Wahlbeck 1999).
Loxapine can be an excellent alternative to clozapine.
Clozapine intoxication can be life-threatening. Outside of the common drug–drug interactions, tobacco smoking, and caffeine consumption, infectious and inflammatory processes are important contributors to clozapine intoxication.
While the majority of quetiapine prescriptions are used for their intended purpose, some patients obtain quetiapine from both legitimate and illicit sources and use this medication as a drug of abuse.
In addition, recent studies have shown a strong potential for misuse and abuse (MUA) of quetiapine beyond Food and Drug Administration-approved indications. This includes drug-seeking behaviors, such as feigning symptoms, motivated by quetiapine and use of quetiapine in conjunction with alcohol.
You should not use quetiapine if you are allergic to it. Quetiapine may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use. Quetiapine is not approved for use by anyone younger than 10 years old.